John Guardiola
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View article: The Threat of Micro-/Nanoplastics to Male Fertility: A Review of the Data and the Importance of Future Research
The Threat of Micro-/Nanoplastics to Male Fertility: A Review of the Data and the Importance of Future Research Open
Micro-/nanoplastics (MNPs) and their associated endocrine-disrupting chemicals (EDCs) have emerged as pervasive environmental pollutants, with growing concern for their impact on male reproductive health. In this review, we synthesize the …
View article: Advanced chronic kidney disease increases the odds of ERCP adverse events but not post-ERCP pancreatitis: a propensity-matched analysis of the US Collaborative Network
Advanced chronic kidney disease increases the odds of ERCP adverse events but not post-ERCP pancreatitis: a propensity-matched analysis of the US Collaborative Network Open
Background Patients with chronic kidney disease (CKD) are at an increased risk choledocholithiasis, requiring intervention with endoscopic retrograde cholangiopancreatography (ERCP). Data on ERCP-related adverse events in this population i…
View article: Artificial Intelligence-Assisted Colonoscopy With or Without Mucosal Exposure Device for Detection of Colorectal Adenomas: A Meta-Analysis
Artificial Intelligence-Assisted Colonoscopy With or Without Mucosal Exposure Device for Detection of Colorectal Adenomas: A Meta-Analysis Open
Artificial intelligence (AI) and mucosal exposure devices like Endocuff have independently improved the adenoma detection rate (ADR) during colonoscopy. This meta-analysis evaluated the combined effect of Endocuff and AI versus AI alone on…
View article: Risk of Post-Polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network
Risk of Post-Polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network Open
Background Studies evaluating the risk of post-polypectomy bleeding (PPB) after colorectal endoscopic mucosal resection (EMR) in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) are limited. Methods This retros…
View article: A new through-the-scope clip with anchor prongs is safe and successful for a variety of endoscopic uses
A new through-the-scope clip with anchor prongs is safe and successful for a variety of endoscopic uses Open
Background and study aims Endoscopic through-the-scope clips (TTSC) are used for hemostasis and closure. We documented the performance of a new TTSC with anchor prongs. Patients and methods We conducted a prospective case series of the new…
View article: P-070 SARS-CoV2 antibody isotypes in seminal fluid of vaccinated men
P-070 SARS-CoV2 antibody isotypes in seminal fluid of vaccinated men Open
Study question Are SARS-CoV2 antibody isotypes detectable in seminal fluid of vaccinated men Summary answer Systemic circulating SARS-CoV2 antibodies are likely to be precluded from transport to seminal plasma following vaccination in male…
View article: Primary lung sarcoma with gastric metastasis and morphological divergence presenting as melena
Primary lung sarcoma with gastric metastasis and morphological divergence presenting as melena Open
A 61-year-old man was admitted to the medical intensive care unit following a 2-week history of weakness, lightheadedness and melena resulting in an acute anaemia. Upper endoscopy revealed multiple large gastric masses without evidence of …
View article: Plasma Metabolomics Analysis of Polyvinyl Chloride Workers Identifies Altered Processes and Candidate Biomarkers for Hepatic Hemangiosarcoma and Its Development
Plasma Metabolomics Analysis of Polyvinyl Chloride Workers Identifies Altered Processes and Candidate Biomarkers for Hepatic Hemangiosarcoma and Its Development Open
Background: High-level occupational vinyl chloride (VC) exposures have been associated with hepatic hemangiosarcoma, which typically develops following a long latency period. Although VC is genotoxic, a more comprehensive mode of action ha…
View article: Leucine-rich repeats and calponin homology containing 4 (Lrch4) regulates the innate immune response
Leucine-rich repeats and calponin homology containing 4 (Lrch4) regulates the innate immune response Open
Toll-like receptors (TLRs) are pathogen-recognition receptors that trigger the innate immune response. Recent reports have identified accessory proteins that provide essential support to TLR function through ligand delivery and receptor tr…