Jane Gunn
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View article: Foundations of the ALIVE National Centre for Mental Health Research Translation: Impact evaluation protocol
Foundations of the ALIVE National Centre for Mental Health Research Translation: Impact evaluation protocol Open
The ALIVE National Centre for Mental Health Research Translation was established in 2021. Funded by the Australian National Health and Medical Research Council's Special Initiative in Mental Health, the Centre aims to foster innovation in …
View article: Supporting primary care practitioners to promote dementia risk reduction in Australian general practice: outcomes of a cross-sectional, non-randomised implementation pilot study
Supporting primary care practitioners to promote dementia risk reduction in Australian general practice: outcomes of a cross-sectional, non-randomised implementation pilot study Open
Background Primary care practitioners worldwide are urged to promote dementia risk reduction as part of preventive care. To facilitate this in Australian primary care, we developed the Umbrella intervention, comprising a waiting room surve…
View article: Understanding Australian general practice patients’ decisions to deprescribe antidepressants in the WiserAD trial: a realist informed approach
Understanding Australian general practice patients’ decisions to deprescribe antidepressants in the WiserAD trial: a realist informed approach Open
Objectives To evaluate how an approach to antidepressant deprescribing works, for whom, and in what contexts by (1) examining the experiences and perceptions of the approach for antidepressant users, (2) identifying the mechanisms of the a…
View article: The Markers in Neuropsychiatric Disorders Study (The MiND Study): moving neurofilament light and other markers into the clinic to improve care for people with symptoms and illnesses of the mind and brain
The Markers in Neuropsychiatric Disorders Study (The MiND Study): moving neurofilament light and other markers into the clinic to improve care for people with symptoms and illnesses of the mind and brain Open
Background Accurate, timely diagnosis of neuropsychiatric symptoms, in particular distinguishing primary psychiatric from neurological disorders and in younger people, can be challenging. Neurofilament light (NfL) and other blood biomarker…
View article: The PRESIDE (PhaRmacogEnomicS In DEpression) Trial: a double-blind randomised controlled trial of pharmacogenomic-informed prescribing of antidepressants on depression outcomes in patients with major depressive disorder in primary care.
The PRESIDE (PhaRmacogEnomicS In DEpression) Trial: a double-blind randomised controlled trial of pharmacogenomic-informed prescribing of antidepressants on depression outcomes in patients with major depressive disorder in primary care. Open
Background: The evidence for the clinical utility of pharmacogenomic (PGx) testing is growing and guidelines exist for the use of PGx testing to inform prescribing of 13 antidepressants. Although previous randomised controlled trials of PG…
View article: <i>Corrigendum to</i> : Use of electronic medical records to monitor the safe and effective prescribing of medicinal cannabis: is it feasible?
<i>Corrigendum to</i> : Use of electronic medical records to monitor the safe and effective prescribing of medicinal cannabis: is it feasible? Open
Background:General practitioners are well positioned to contribute to the pharmacovigilance of medical cannabis via the general practice electronic medical record (EMR). The aim of this research is to interrogate de-identified patient data…
View article: Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of the <i>diamond</i> longitudinal study
Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of the <i>diamond</i> longitudinal study Open
Background: Current treatment guidelines advise that the deprescribing of antidepressants should occur around 6 months post-remission of symptoms. However, this is not routinely occurring in clinical practice, with between 30% and 50% of a…
View article: General Practice Patients’ Experiences and Perceptions of the WiserAD Structured Web-Based Support Tool for Antidepressant Deprescribing: Protocol for a Mixed Methods Case Study With Realist Evaluation
General Practice Patients’ Experiences and Perceptions of the WiserAD Structured Web-Based Support Tool for Antidepressant Deprescribing: Protocol for a Mixed Methods Case Study With Realist Evaluation Open
Background Research suggests that the rapid increase in worldwide antidepressant use is mainly due to a rise in long-term and potentially inappropriate use. It has been suggested that 1 in 3 antidepressant users among general practice pati…
View article: A mixed methods case study realist evaluation of the WiserAD structured online support tool for antidepressant deprescribing in general practice: A study protocol (Preprint)
A mixed methods case study realist evaluation of the WiserAD structured online support tool for antidepressant deprescribing in general practice: A study protocol (Preprint) Open
BACKGROUND Research suggests that the rapid increase in worldwide antidepressant use is mainly due to a rise in long-term and potentially inappropriate use. General practice patients who are no longer experiencing clinical benefit from th…
View article: Use of electronic medical records to monitor the safe and effective prescribing of medicinal cannabis: is it feasible?
Use of electronic medical records to monitor the safe and effective prescribing of medicinal cannabis: is it feasible? Open
Background General practitioners are well positioned to contribute to the pharmacovigilance of medical cannabis via the general practice electronic medical record (EMR). The aim of this research is to interrogate de-identified patient data…
View article: Dementia Risk Reduction in Primary Care: A Scoping Review of Clinical Guidelines Using a Behavioral Specificity Framework
Dementia Risk Reduction in Primary Care: A Scoping Review of Clinical Guidelines Using a Behavioral Specificity Framework Open
Background: Primary care practitioners are being called upon to work with their patients to reduce dementia risk. However, it is unclear who should do what with whom, when, and under what circumstances. Objective: This scoping review aimed…
View article: Economic evaluation of the Target-D platform to match depression management to severity prognosis in primary care: A within-trial cost-utility analysis
Economic evaluation of the Target-D platform to match depression management to severity prognosis in primary care: A within-trial cost-utility analysis Open
Background Target-D, a new person-centred e-health platform matching depression care to symptom severity prognosis (minimal/mild, moderate or severe) has demonstrated greater improvement in depressive symptoms than usual care plus attentio…
View article: The impact of removing financial incentives and/or audit and feedback on chlamydia testing in general practice: A cluster randomised controlled trial (ACCEPt-able)
The impact of removing financial incentives and/or audit and feedback on chlamydia testing in general practice: A cluster randomised controlled trial (ACCEPt-able) Open
Background Financial incentives and audit/feedback are widely used in primary care to influence clinician behaviour and increase quality of care. While observational data suggest a decline in quality when these interventions are stopped, t…
View article: Patient reported self‐help strategies and the perceived benefits for managing sub‐threshold depressive symptoms: A nested qualitative study of Australian primary care attendees
Patient reported self‐help strategies and the perceived benefits for managing sub‐threshold depressive symptoms: A nested qualitative study of Australian primary care attendees Open
Some of the reported self-management strategies aligned with evidence-based approaches such as physical activity and mindfulness for mental health symptom management. These findings can inform low-intensity interventions within stepped car…
View article: Assessing the suitability of general practice electronic health records for clinical prediction model development: a data quality assessment
Assessing the suitability of general practice electronic health records for clinical prediction model development: a data quality assessment Open
Background The use of general practice electronic health records (EHRs) for research purposes is in its infancy in Australia. Given these data were collected for clinical purposes, questions remain around data quality and whether these dat…
View article: Implementation of medicinal cannabis in Australia: innovation or upheaval? Perspectives from physicians as key informants, a qualitative analysis
Implementation of medicinal cannabis in Australia: innovation or upheaval? Perspectives from physicians as key informants, a qualitative analysis Open
Objective We sought to explore physician perspectives on the prescribing of cannabinoids to patients to gain a deeper understanding of the issues faced by prescriber and public health advisors in the rollout of medicinal cannabis. Design A…
View article: Deprescribing intervention activities mapped to guiding principles for use in general practice: a scoping review
Deprescribing intervention activities mapped to guiding principles for use in general practice: a scoping review Open
Objective To identify and characterise activities for deprescribing used in general practice and to map the identified activities to pioneering principles of deprescribing. Setting Primary care. Data sources Medline, EMBASE (Ovid), CINAHL,…
View article: The CORE study—An adapted mental health experience codesign intervention to improve psychosocial recovery for people with severe mental illness: A stepped wedge cluster randomized‐controlled trial
The CORE study—An adapted mental health experience codesign intervention to improve psychosocial recovery for people with severe mental illness: A stepped wedge cluster randomized‐controlled trial Open
Background Mental health policies outline the need for codesign of services and quality improvement in partnership with service users and staff (and sometimes carers), and yet, evidence of systematic implementation and the impacts on healt…
View article: Moving from “let’s fix them” to “actually listen”: the development of a primary care intervention for mental-physical multimorbidity
Moving from “let’s fix them” to “actually listen”: the development of a primary care intervention for mental-physical multimorbidity Open
Background Effective person-centred interventions are needed to support people living with mental-physical multimorbidity to achieve better health and wellbeing outcomes. Depression is identified as the most common mental health condition …
View article: Towards optimising chronic kidney disease detection and management in primary care: Underlying theory and protocol for technology development using an Integrated Knowledge Translation approach
Towards optimising chronic kidney disease detection and management in primary care: Underlying theory and protocol for technology development using an Integrated Knowledge Translation approach Open
Worldwide, Chronic Kidney Disease (CKD), directly or indirectly, causes more than 2.4 million deaths annually with symptoms generally presenting late in the disease course. Clinical guidelines support the early identification and treatment…
View article: THE RANZCP EARLY CAREER PSYCHIATRIST AWARD - NEUROFILAMENT LIGHT CHAIN IN NEURODEGENERATIVE AND PSYCHIATRIC DISORDERS: A SIMPLE DIAGNOSTIC TEST LIKE A 'C-REACTIVE PROTEIN' FOR THE BRAIN
THE RANZCP EARLY CAREER PSYCHIATRIST AWARD - NEUROFILAMENT LIGHT CHAIN IN NEURODEGENERATIVE AND PSYCHIATRIC DISORDERS: A SIMPLE DIAGNOSTIC TEST LIKE A 'C-REACTIVE PROTEIN' FOR THE BRAIN Open
THE RANZCP EARLY CAREER PSYCHIATRIST AWARD - NEUROFILAMENT LIGHT CHAIN IN NEURODEGENERATIVE AND PSYCHIATRIC DISORDERS: A SIMPLE DIAGNOSTIC TEST LIKE A 'C-REACTIVE PROTEIN' FOR THE BRAIN
View article: Matching depression management to severity prognosis in primary care: results of the Target-D randomised controlled trial
Matching depression management to severity prognosis in primary care: results of the Target-D randomised controlled trial Open
Background Mental health treatment rates are increasing, but the burden of disease has not reduced. Tools to support efficient resource distribution are required. Aim To investigate whether a person-centred e-health (Target-D) platform mat…