John Holian
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View article: Factors influencing patients to choose one obesity treatment over another: a qualitative study
Factors influencing patients to choose one obesity treatment over another: a qualitative study Open
Background When deciding a treatment option for the disease of obesity, knowing what the patient’s preferences are and what factors have influenced them can support healthcare professionals (HCPs) in tailoring their management plan. Little…
View article: Improving kidney care for people with severe mental health difficulties: A thematic analysis of personal and family members’ perspectives
Improving kidney care for people with severe mental health difficulties: A thematic analysis of personal and family members’ perspectives Open
People with severe mental health difficulties (SMHDs) often have poorer access to kidney healthcare. To better understand the barriers and facilitators to kidney healthcare for this population, we conducted interviews with nine individuals…
View article: Patient perspectives about treatment preferences for obesity with complications
Patient perspectives about treatment preferences for obesity with complications Open
Objective Obesity and many of its comorbidities can be improved by nutritional therapy, lifestyle modification, pharmacotherapy, and surgical intervention. Relatively little is known about patients' preferences for the range of obesity tre…
View article: Improving kidney care for people with severe mental health difficulties: a thematic analysis of twenty-two healthcare providers’ perspectives
Improving kidney care for people with severe mental health difficulties: a thematic analysis of twenty-two healthcare providers’ perspectives Open
Introduction People with severe mental health difficulties (SMHDs) and concurrent kidney disease have less access to quality kidney care and worse clinical outcomes. Our research investigates the barriers and facilitators to effective kidn…
View article: High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland
High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland Open
Background People with chronic kidney disease (CKD) experience high levels of psychological distress, which is associated with higher mortality and adverse health outcomes. Little is known about the rates of a range of mental health diffic…
View article: ANCA-associated vasculitis in Ireland: a multi-centre national cohort study
ANCA-associated vasculitis in Ireland: a multi-centre national cohort study Open
Background: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare multisystem autoimmune disease. There is a need for interoperable national registries to enable reporting of real-world long-term outcomes and the…
View article: Extended data for 'ANCA-associated vasculitis in Ireland: a multi-centre national cohort study'
Extended data for 'ANCA-associated vasculitis in Ireland: a multi-centre national cohort study' Open
Background: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare multisystem autoimmune disease. There is a need for interoperable national registries to enable reporting of real-world long-term outcomes and the…
View article: POS-072 A PROSPECTIVE AUDIT OF THE CLINICAL IMPLEMENTATION OF URINE NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) AS A BIOMARKER OF ACUTE KIDNEY INJURY IN HOSPITALISED PATIENTS
POS-072 A PROSPECTIVE AUDIT OF THE CLINICAL IMPLEMENTATION OF URINE NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) AS A BIOMARKER OF ACUTE KIDNEY INJURY IN HOSPITALISED PATIENTS Open
Novel acute kidney injury (AKI) biomarkers have been shown to improve diagnostic accuracy, but reports of use in standard clinical practice are rare. The objective of this audit is to evaluate the clinical utility of urine Neutrophil gelat…
View article: Primary adrenal lymphoma presenting with symptomatic hypercalcaemia
Primary adrenal lymphoma presenting with symptomatic hypercalcaemia Open
A 66 year old male, originally from the Philippines, was referred to the emergency department with nausea, vomiting, weight loss and right flank pain. His past medical history was significant for hypertension, gout and stage 3b chronic kid…
View article: The Clinical Application of Urine Soluble CD163 in ANCA-Associated Vasculitis
The Clinical Application of Urine Soluble CD163 in ANCA-Associated Vasculitis Open
Significance Statement In ANCA-associated vasculitis (AAV), noninvasive biomarkers of active renal inflammation, such as urinary soluble CD163, are needed for early detection of active disease before irreversible end organ damage occurs. C…
View article: POS-072 PRACTICAL EXPERIENCE WITH THE IMPLEMENTATION OF NGAL FOR AKI DIAGNOSIS IN A CLINICAL SETTING
POS-072 PRACTICAL EXPERIENCE WITH THE IMPLEMENTATION OF NGAL FOR AKI DIAGNOSIS IN A CLINICAL SETTING Open
Kidney injury biomarkers for AKI have been shown to detect AKI earlier, predict progression and better discriminate etiology compared to serum creatinine. These biomarkers have been studied in various clinical trials, but their implementat…
View article: Supplementary Material for: Clinical Implementation and Initial Experience of Neutrophil Gelatinase-Associated Lipocalin Testing for the Diagnostic and Prognostic Assessment of Acute Kidney Injury Events in Hospitalized Patients
Supplementary Material for: Clinical Implementation and Initial Experience of Neutrophil Gelatinase-Associated Lipocalin Testing for the Diagnostic and Prognostic Assessment of Acute Kidney Injury Events in Hospitalized Patients Open
Introduction: The use of novel kidney injury biomarkers has been shown to improve diagnostic assessment and prognostic prediction in various populations with acute kidney injury (AKI), but their use in a standard clinical practice have bee…
View article: Obesity is common in chronic kidney disease and associates with greater antihypertensive usage and proteinuria: evidence from a cross‐sectional study in a <scp>tertiary nephrology centre</scp>
Obesity is common in chronic kidney disease and associates with greater antihypertensive usage and proteinuria: evidence from a cross‐sectional study in a <span>tertiary nephrology centre</span> Open
Summary Obesity is a treatable risk factor for chronic kidney disease progression. We audited the reporting of body‐mass index in nephrology outpatient clinics to establish the characteristics of individuals with obesity in nephrology prac…
View article: P1733MINERAL BONE DISEASE (MBD) IS THE POST KIDNEY TRANSPLANTATION POPULATION
P1733MINERAL BONE DISEASE (MBD) IS THE POST KIDNEY TRANSPLANTATION POPULATION Open
Background and Aims Patients with ESRD have a 4-fold higher risk of fracture compared to the general population. (1) Transplant bone disease is a combination of mineral bone disease sustained pre transplantation and damage incurred post tr…
View article: SAT-185 Primary Adrenal Lymphoma Presenting with Symptomatic Hypercalcaemia
SAT-185 Primary Adrenal Lymphoma Presenting with Symptomatic Hypercalcaemia Open
Introduction: Primary adrenal lymphoma (PAL) is a rare cause of adrenal enlargement with approximately 200 cases reported in the literature to date. It tends to affect elderly men and has a high incidence of bilateral involvement at diagno…
View article: 036. USCD163 IS AN EARLY PREDICTOR OF TREATMENT RESPONSE IN CRESCENTIC GLOMERULONEPHRITIS
036. USCD163 IS AN EARLY PREDICTOR OF TREATMENT RESPONSE IN CRESCENTIC GLOMERULONEPHRITIS Open
Background: Approximately 10-20% of patients with granulomatosis with polyangiitis (GPA) are ANCA-negative.The aim of the study was to compare the clinical characteristics and treatment outcomes of ANCA-positive and ANCA-negative forms of …
View article: FP551REAL-TIME VOLUME ASSESSMENT TO GUIDE APPROPRIATE ULTRAFILTRATION IN HAEMODIALYSIS PATIENTS
FP551REAL-TIME VOLUME ASSESSMENT TO GUIDE APPROPRIATE ULTRAFILTRATION IN HAEMODIALYSIS PATIENTS Open
patients with normal renal function (NRF), with chronic renal insufficiency (CRI) and dialysis dependent (DD) patients.The 9-month target lesion revascularization (TLR) rate was the primary endpoint whereas the 9-month major adverse cardia…
View article: Spatial and Temporal Clustering of Anti-Glomerular Basement Membrane Disease
Spatial and Temporal Clustering of Anti-Glomerular Basement Membrane Disease Open
Background and objectives An environmental trigger has been proposed as an inciting factor in the development of anti-GBM disease. This multicenter, observational study sought to define the national incidence of anti-GBM disease during an …