John Ikechukwu Ihedioha
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View article: Impact of multiple Lasota vaccinations on the haematological parameters of pullets infected with velogenic Newcastle disease virus
Impact of multiple Lasota vaccinations on the haematological parameters of pullets infected with velogenic Newcastle disease virus Open
Newcastle disease (ND) is an important disease of poultry worldwide. This study aimed to evaluate the impact of multiple ND Lasota vaccinations on haematological parameters of pullets before and after experimental infection with velogenic …
View article: Experimental Salmonella Gallinarum Infection in Young Pullets: Correlation of Serum Biochemistry with Organ Pathology
Experimental Salmonella Gallinarum Infection in Young Pullets: Correlation of Serum Biochemistry with Organ Pathology Open
The effect of experimental Salmonella Gallinarum infection on the serum biochemistry of young pullets was assessed, and correlation was made with lesions in the target organs. 50 young pullets, at 7 weeks of age, were randomly assigned to …
View article: Cardiac effusion and serum biochemical abnormalities of Salmonella gallinarum infection in point of lay pullets
Cardiac effusion and serum biochemical abnormalities of Salmonella gallinarum infection in point of lay pullets Open
The aim of this study was to evaluate some lesions and biochemical abnormalities of fowl typhoid (FT) in point of lay (POL) pullets. Fifty POL pullets were randomly assigned to two groups of 25 infected orally with S. gallinarum (109 S. ga…
View article: A phase II study evaluating low dose ipilimumab in combination with pembrolizumab in patients with melanoma brain metastases
A phase II study evaluating low dose ipilimumab in combination with pembrolizumab in patients with melanoma brain metastases Open
View article: Experimental Velogenic Viscerotropic Newcastle Disease Virus Infection in Chickens Immunologically Impaired by Treatment with Cyclophosphamide
Experimental Velogenic Viscerotropic Newcastle Disease Virus Infection in Chickens Immunologically Impaired by Treatment with Cyclophosphamide Open
This study investigated whether lymphocytic depletion following chemical bursectomy influenced the severity of infection and development of lesions in chickens challenged with velogenic viscerotropic Newcastle disease virus (vvNDV). Cocker…
View article: HEPATOPROTECTIVE EFFECTS OF METHANOL LEAF EXTRACT OF PTEROCARPUS SANTALINOIDES DC ON ACETAMINOPHEN-INDUCED LIVER DAMAGE IN ALBINO RATS (RATTUS NORVEGICUS)
HEPATOPROTECTIVE EFFECTS OF METHANOL LEAF EXTRACT OF PTEROCARPUS SANTALINOIDES DC ON ACETAMINOPHEN-INDUCED LIVER DAMAGE IN ALBINO RATS (RATTUS NORVEGICUS) Open
This study investigated the effects of methanol leaf extract of Pterocarpus santalinoides on acetaminophen (APAP)-induced sub-acute liver damage in albino rats. Fresh leaves of P. santalinoides used for the study were collected, dried unde…
View article: Postexposure Pestes-des-petits-ruminants vaccination with oxytetracycline therapy mitigates severe disease and increases survivability in natural infections
Postexposure Pestes-des-petits-ruminants vaccination with oxytetracycline therapy mitigates severe disease and increases survivability in natural infections Open
The potentials of post-exposure intranasal (IN) and subcutaneous (SC) Peste des petits ruminants vaccination (PPRVc) with concurrent oxytetracycline (oxytet.) treatment in the management of PPR outbreaks in goats were investigated. Twenty-…
View article: Survey of Animal Neoplastic Cases Diagnosed in Nigerian Veterinary Teaching Hospitals, 2000–2017
Survey of Animal Neoplastic Cases Diagnosed in Nigerian Veterinary Teaching Hospitals, 2000–2017 Open
Incidence data from 17-year veterinary neoplasm surveillance and registration were reviewed. Most of the neoplastic cases diagnosed in Nigerian veterinary teaching hospitals (VTHs) were in the avian (49%) and canine species (44%). Fewer ca…
View article: Effects of Hydromethanol Extract of Stem Bark of Anacardium occidentale on Gross and Histopathological changes Associated with Experimental Velogenic Newcastle Disease Virus Infection in Chickens
Effects of Hydromethanol Extract of Stem Bark of Anacardium occidentale on Gross and Histopathological changes Associated with Experimental Velogenic Newcastle Disease Virus Infection in Chickens Open
View article: The effect of dietary supplementation with aqueous extract of freshly harvested Talinum triangulare (waterleaf) plant on the haematology, serum biochemistry and carcass quality of broilers
The effect of dietary supplementation with aqueous extract of freshly harvested Talinum triangulare (waterleaf) plant on the haematology, serum biochemistry and carcass quality of broilers Open
A study was conducted to investigate the effect of dietary supplementation with Talinum triangulare (waterleaf) plant extract on broiler production and meat quality. A total of 75-day-old broiler chicks were used for a 35-day study which c…
View article: Supplementation of hen diets with dried or freshly harvested Talinum triangulare: the effect on egg production and egg lipid profile
Supplementation of hen diets with dried or freshly harvested Talinum triangulare: the effect on egg production and egg lipid profile Open
This study investigated the comparative effects of administration of dried and fresh Talinum triangulare (Tt) plant supplements on the egg production and egg quality of laying hens. Two hundred and ten pullets, purchased at the age of 18 w…
View article: Effects of Calocybe indica Mushroom on Oxidative Stress and Hematological Alterations in Rats with Testosterone-induced Experimental Benign Prostatic Hyperplasia
Effects of Calocybe indica Mushroom on Oxidative Stress and Hematological Alterations in Rats with Testosterone-induced Experimental Benign Prostatic Hyperplasia Open
This study was designed to evaluate the protective effect of Calocybe indica extract (CLE) on testosterone propionate (TP)-induced hematological changes and oxidative stress in rats. The rats were grouped into six equal groups of ten rats …
View article: Inhibitory effects of <i>Calocybe indica</i> macrofungi on experimental benign prostatic hyperplasia in rats.
Inhibitory effects of <i>Calocybe indica</i> macrofungi on experimental benign prostatic hyperplasia in rats. Open
Administration of C. indica extract suppressed the pathophysiological effects of benign prostatic hyperplasia in rats. Thus, C. indica mushroom is a potential pharmacological candidate for the management of BPH in man or dogs.
View article: COVID-19 Vaccine: Vaccine Acceptance, Risk Perception, and Attitude Towards Vaccination among College Students and Staff in the Southeastern Universities, Nigeria
COVID-19 Vaccine: Vaccine Acceptance, Risk Perception, and Attitude Towards Vaccination among College Students and Staff in the Southeastern Universities, Nigeria Open
University students occupy a strategic position in the spread of coronavirus disease 19 (COVID-19) as they regularly travel around different locations with differing prevalence of the disease. This study was carried out to evaluate the acc…
View article: Correction to: Seroprevalence, hematological and biochemical alterations in Brucella-seropositive Muturu cattle in Nigeria
Correction to: Seroprevalence, hematological and biochemical alterations in Brucella-seropositive Muturu cattle in Nigeria Open
View article: Infection of West African Dwarf Rams With Trypanosoma Brucei Brucei and Trypanosoma Congolense Significantly Alter Serum Electrolytes, Redox Balance, Sperm Parameters, And Gonadal Morphology
Infection of West African Dwarf Rams With Trypanosoma Brucei Brucei and Trypanosoma Congolense Significantly Alter Serum Electrolytes, Redox Balance, Sperm Parameters, And Gonadal Morphology Open
Trypanotolerance of the West African dwarf (WAD) breeds may not rule out significant pathophysiological changes that may affect productivity. In this study, the effects of infection of WAD rams with Trypanosoma brucei brucei (Tbb) and Tryp…
View article: Haemato-biochemical alterations and acute toxicity study of hydro-methanol root extract of Anacardium occidentale in cockerels
Haemato-biochemical alterations and acute toxicity study of hydro-methanol root extract of Anacardium occidentale in cockerels Open
The study evaluated the haemato-biochemical alterations and acute toxicity of hydro-methanol root extract of Anarcaduim occidentale (AO) in cockerels. Forty chickens randomly assigned into four groups (A, B, C and D) of 10 birds each were …
View article: Molecular detection of Trypanosoma species and haematological alterations in four trypanosome-infected Nigerian horses
Molecular detection of Trypanosoma species and haematological alterations in four trypanosome-infected Nigerian horses Open
Trypanosomes cause anaemia and are responsible for widespread morbidity and mortality particularly in imported breeds of animals found in sub-tropical and tropical parts of the world. Light microscopy and polymerase chain reaction (PCR) we…
View article: Hematological Changes Associated with Pregnancy in Domestic Sows (Suis domesticus)
Hematological Changes Associated with Pregnancy in Domestic Sows (Suis domesticus) Open
Background: Pregnancy involves complex biological interaction and communication between the developing conceptus and maternal uterus, which may alter the blood cellular elements. The present investigation evaluated the hematological change…
View article: Comparative evaluation of the hepatoprotective activity of methanolleaf extracts of Pterocarpus santalinoides DC obtained by cold maceration and Soxhlet extraction techniques
Comparative evaluation of the hepatoprotective activity of methanolleaf extracts of Pterocarpus santalinoides DC obtained by cold maceration and Soxhlet extraction techniques Open
Objectives: This study compared the hepatoprotective activity of Pterocarpus santalinoides cold maceration extract (PSCME) with P. santalinoides Soxhlet extract (PSSE). Materials and Methods: Phytochemical constituents of both extracts wer…
View article: Hepatoprotective effects of methanol leaf extract of pterocarpus santalinoides DC on acetaminophen-induced liver damage in Albino rats (Rattus norvegicus)
Hepatoprotective effects of methanol leaf extract of pterocarpus santalinoides DC on acetaminophen-induced liver damage in Albino rats (Rattus norvegicus) Open
The effects of methanol leaf extract of Pterocarpus santalinoides DC was investigated on acetaminophen (APAP)-induced sub-acute liver damage (hepatotoxicity) in albino rats. Forty two adultmale albino ratswere used for the study, 12 for th…
View article: Haematology, serum biochemistry and histopathological findings associated with sub-chronic administration of methanol leaf extract of Pterocarpus santalinoides DC in albino rats
Haematology, serum biochemistry and histopathological findings associated with sub-chronic administration of methanol leaf extract of Pterocarpus santalinoides DC in albino rats Open
The effects of sub-chronic administration of Pterocarpus santalinoides methanol leaf extract (PSME) on haematology, serum biochemistry and histology of albino rats were evaluated. Twenty female albino rats, randomly assigned into four grou…
View article: Evaluation of the Efficacy of a Combination of Artemether and Diminazene Aceturate Therapy in Experimental Trypanosoma brucei Infection in Rats
Evaluation of the Efficacy of a Combination of Artemether and Diminazene Aceturate Therapy in Experimental Trypanosoma brucei Infection in Rats Open
This study evaluated the efficacy of a combination of artemether and diminazene aceturate therapy in experimental Trypanosoma brucei infection in rats. Thirty five male albino rats used for the study were randomly assigned to seven groups …
View article: An appraisal of Canine Transmissible Venereal Tumour with emphasis on molecular biology and pathology
An appraisal of Canine Transmissible Venereal Tumour with emphasis on molecular biology and pathology Open
Canine transmissible venereal tumour (CTVT) is a contagious tumour of dogs, transmitted via coitus or coital behaviour which in some cases spreads by metastasis but primarily, CTVT appears as reddish soft nodules or papilla, protruding fro…
View article: Reference values for certain serum biochemical markers of liver damage in apparently healthy Red Sokoto goats
Reference values for certain serum biochemical markers of liver damage in apparently healthy Red Sokoto goats Open
The Red Sokoto goat (RSG) is the most preponderant of all the breeds of goats in Nigeria. There is dearth of information regarding the reference values for serum biochemical markers of liver damage in this breed. This study demonstrated th…
View article: Triple La Sota re‐vaccinations can protect laying chickens for 3 months against drop in egg production caused by velogenic viscerotropic Newcastle disease virus infection
Triple La Sota re‐vaccinations can protect laying chickens for 3 months against drop in egg production caused by velogenic viscerotropic Newcastle disease virus infection Open
One hundred and ten Isa Brown layers were vaccinated with La Sota, once at point of lay at 18 weeks and three times at peak of lay which occurred at 27–29 weeks of age. Thereafter, they were weekly monitored for haemagglutination inhibitio…
View article: Some Biochemical Perturbations May Modify the Understanding of Trypanotolerance in the West African Dwarf Sheep Infected With <i>Trypanosoma brucei brucei</i> and <i>Trypanosoma congolense</i>
Some Biochemical Perturbations May Modify the Understanding of Trypanotolerance in the West African Dwarf Sheep Infected With <i>Trypanosoma brucei brucei</i> and <i>Trypanosoma congolense</i> Open
Trypanosomes are single-celled protozoa that cause severe diseases in both humans and livestock in sub-Saharan African countries. The disease in the West African Dwarf (WAD) sheep is often neglected due to the issue of trypanotolerance. Th…
View article: Evaluation of the hematological and clinical biochemical markers of stress in broiler chickens
Evaluation of the hematological and clinical biochemical markers of stress in broiler chickens Open
Background and Aim: Stress significantly affects health and productivity of animals. There is need for affordable and easy-to-assay markers of physiological stress in broilers. This study evaluated hematological and serum biochemical marke…
View article: Hepatoprotective and antioxidant activities of Pterocarpus santalinoides methanol leaf extract
Hepatoprotective and antioxidant activities of Pterocarpus santalinoides methanol leaf extract Open
This study evaluated the hepatoprotective and antioxidant activities (AA) of Pterocarpus santalinoides methanol leaf extract (PSMLE) on carbon tetrachloride (CCl4)-induced hepatotoxicity in albino rats. Thirty male albino rats randomly ass…
View article: Pullets had higher bursal and thymic weight indices and more antibody response to La Sota vaccination than broiler chickens (<i>Gallus gallus domesticus</i>)
Pullets had higher bursal and thymic weight indices and more antibody response to La Sota vaccination than broiler chickens (<i>Gallus gallus domesticus</i>) Open
This study investigated the immune responses to La Sota vaccination, used in protection of chickens against Newcastle disease, in light weight type breeds of chickens (pullets) and heavy weight type breeds of chickens (broilers) used in co…