Explanipedia

Neuroplastics approach to cerebrovascular bypass surgery: the way forward for centres with small to medium volume caseload Open

Jia Xu Lim, C. Goh, R. Wee, John J.Y. Zhang, Yee Siang Ong , et al. · 2025

Endovascular coiling versus neurosurgical clipping in the management of aneurysmal subarachnoid haemorrhage in the elderly: a multicenter cohort study Open

Keng Siang Lee, Isabel Siow, Lily WY Yang, Aaron SC Foo, John J.Y. Zhang , et al. · 2024

The comparability of endovascular coiling over neurosurgical clipping has not been firmly established in elderly patients with aneurysmal subarachnoid haemorrhage (aSAH). Data were obtained from all patients with aSAH aged ≥60 across three…

Corrigendum to ‘Cost-Effectiveness of Robot-Assisted Total Knee Arthroplasty: A Markov Decision Analysis’ [Volume 38, Issue 8, August 2023, Pages 1434-1437] Open

John J.Y. Zhang, Jerry Yongqiang Chen, Darren Keng Jin Tay, Hee Nee Pang, Seng Jin Yeo , et al. · 2023

Surgical revascularizations for pediatric moyamoya: a systematic review, meta-analysis, and meta-regression analysis Open

Keng Siang Lee, John J.Y. Zhang, Sanjay Bhate, Vijeya Ganesan, Dominic Thompson , et al. · 2023

Introduction There is no clear consensus regarding the technique of surgical revascularization for moyamoya disease and syndrome (MMD/MMS) in the pediatric population. Previous meta-analyses have attempted to address this gap in literature…

Clinical Outcomes of 3D-Printed Bioresorbable Scaffolds for Bone Tissue Engineering—A Pilot Study on 126 Patients for Burrhole Covers in Subdural Hematoma Open

Emma Min Shuen Toh, Ashiley Annushri Thenpandiyan, Aaron Song Chuan Foo, John J.Y. Zhang, Mervyn Jun Rui Lim , et al. · 2022

Burrhole craniostomy is commonly performed for subdural hematoma (SDH) evacuation, but residual scalp depressions are often cosmetically suboptimal for patients. OsteoplugTM, a bioresorbable polycaprolactone burrhole cover, was introduced …

Seizure outcome after resection of insular glioma: a systematic review, meta-analysis, and institutional experience Open

John J.Y. Zhang, Keng Siang Lee, Doris D. Wang, Shawn L. Hervey‐Jumper, Mitchel S. Berger · 2022

OBJECTIVE Gliomas arising from the insular cortex can be epileptogenic, with a significant proportion of patients having medically refractory epilepsy. The impact of surgery on seizure control for such tumors is not well established. In th…

Tenets for the Proper Conduct and Use of Meta-Analyses: A Practical Guide for Neurosurgeons Open

Keng Siang Lee, John J.Y. Zhang, Vincent Diong Weng Nga, Cheng Han Ng, Bee Choo Tai , et al. · 2022

Neurosurgeons today are inundated with rapidly amassing neurosurgical research publications. Systematic reviews and meta-analyses have consequently surged in popularity because, when executed properly, they constitute a high level of evide…

A systematic review and meta-analysis of the association between cyproterone acetate and intracranial meningiomas Open

Keng Siang Lee, John J.Y. Zhang, Ramez Kirollos, Thomas Santarius, Vincent Diong Weng Nga , et al. · 2022

The influence of exposure to hormonal treatments, particularly cyproterone acetate (CPA), has been posited to contribute to the growth of meningiomas. Given the widespread use of CPA, this systematic review and meta-analysis attempted to a…

Endotracheal intubation—still the gold standard in out-of-hospital cardiac arrest airway management? Open

Jonathan Teng Fai Loke, Seth En Teoh, John J.Y. Zhang, Yoshio Masuda · 2021

RADI-06. Gamma knife surgery for brain stem metastases Open

Choo Heng Tan, Bengt Karlsson, Shilin Wang, John J.Y. Zhang, Yvonne Ang , et al. · 2021

Introduction Gamma Knife Surgery (GKS) is widely used for treatment of brainstem metastases (BSMs) with or without whole bran radiation therapy (WBRT). We hypothesized that BSMs treated with GKS using lower doses and omitting WBRT result i…

Reply to Letter to Editor Open

Isabel Siow, Keng Siang Lee, John J.Y. Zhang, Seyed Ehsan Saffari, Adeline Su Lyn Ng , et al. · 2021

Encephalitis as a neurological complication of COVID‐19: A systematic review and meta‐analysis of incidence, outcomes, and predictors Open

Isabel Siow, Keng Siang Lee, John J.Y. Zhang, Seyed Ehsan Saffari, Adeline Su Lyn Ng · 2021

Background and purpose Although COVID‐19 predominantly affects the respiratory system, recent studies have reported the occurrence of neurological disorders such as stroke in relation to COVID‐19 infection. Encephalitis is an inflammatory …

135 Direct and Combined Revascularization Versus Indirect Revascularization in the Treatment of Moyamoya Disease: A Systematic Review and Meta-Analysis Open

Keng Siang Lee, Mario Teo, John J.Y. Zhang, Gary K. Steinberg · 2021

Introduction The goal of surgical revascularization of moyamoya disease (MMD) is to augment cerebral blood flow and prevent intracranial haemorrhage. This study aimed to compare direct and combined versus indirect bypasses with regard to p…

The evolution of intracranial aneurysm treatment techniques and future directions Open

Keng Siang Lee, John J.Y. Zhang, Vincent Nguyen, Julian Xinguang Han, Jeremiah D. Johnson , et al. · 2021

P44 Direct and Combined Revascularization Versus Indirect Revascularization in the Treatment of Moyamoya Disease: A Systematic Review and Meta-Analysis Open

Keng Siang Lee, John J.Y. Zhang, Mario Teo, Gary K. Steinberg · 2021

Introduction There is currently no definite consensus regarding the surgical treatment of moyamoya disease (MMD). This study aimed to compare direct and combined versus indirect bypasses with regard to perioperative complications in pediat…

Diagnostic performance of COVID‐19 serological assays during early infection: A systematic review and meta‐analysis of 11 516 samples Open

John J.Y. Zhang, Keng Siang Lee, Chee Wui Ong, M Y Chan, Li Wei Ang , et al. · 2021

Objective The use of coronavirus disease 2019 (COVID‐19) serological testing to diagnose acute infection or determine population seroprevalence relies on understanding assay accuracy during early infection. We aimed to evaluate the diagnos…

Neurosurgical clipping versus endovascular coiling for unruptured and ruptured distal anterior cerebral artery aneurysms: a systematic review and meta-analysis Open

K. Lee, John J.Y. Zhang, Mario Teo · 2021

Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-Analysis of Incidence, Outcomes and Predictors Open

Isabel Siow, Keng Siang Lee, John J.Y. Zhang, Seyed Ehsan Saffari, Adeline Su Lyn Ng , et al. · 2020

Letter to the Editor: “Medical Student Concerns Relating to Neurosurgery Education During COVID-19” Open

Keng Siang Lee, John J.Y. Zhang · 2020

Potential challenges in managing obstetrical patients with coronavirus disease 2019 Open

Kyla Ng Yin, Keng Siang Lee, John J.Y. Zhang · 2020

Risk Factors for Severe Disease and Efficacy of Treatment in Patients Infected With COVID-19: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis Open

John J.Y. Zhang, Keng Siang Lee, Li Wei Ang, Yee‐Sin Leo, Barnaby Edward Young · 2020

The coronavirus disease 2019 (COVID-19) pandemic spread globally in the beginning of 2020. At present, predictors of severe disease and the efficacy of different treatments are not well understood. We conducted a systematic review and meta…

Letter to the Editor. Healthy competition Open

John J.Y. Zhang, Keng Siang Lee · 2020

Extracorporeal membrane oxygenation in pregnancy and the postpartum period: a systematic review of case reports Open

Ju Lynn Ong, John J.Y. Zhang, Roberto Lorusso, Graeme MacLaren, Kollengode Ramanathan · 2020

Freehand insertion of external ventricular drainage catheter: Evaluation of accuracy in a single center Open

K. Lee, John J.Y. Zhang, Nagarjun Bolem, May Ying Leong, Chun Peng Goh , et al. · 2020

Introduction: External ventricular drain (EVD) placement is the gold standard for managing acute hydrocephalus. Freehand EVD, using surface anatomical landmarks, is performed for ventricular cannulation due to its simplicity and efficiency…

Letter: Cost-Effectiveness Research in Neurosurgery: We Can and We Must Open

John J.Y. Zhang, Keng Siang Lee · 2020

To the Editor: We read with great interest the article by Stein.1 We would like to congratulate Dr Stein for doing a very commendable job in bringing to light a pertinent area for improvement in neurosurgical academia, that is, the paucity…

Awake craniotomy for resection of supratentorial glioblastoma: a systematic review and meta-analysis Open

John J.Y. Zhang, Keng Siang Lee, Mathew Voisin, Shawn L. Hervey‐Jumper, Mitchel S. Berger , et al. · 2020

Background The goal of glioblastoma (GBM) surgery is to maximize the extent of resection (EOR) while minimizing postoperative neurological complications. Awake craniotomy (AC) has been demonstrated to achieve this goal for low-grade glioma…

John J.Y. Zhang YOU? Author Swipe