John L. Vaughn
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View article: Association of CAR-T approval on outcomes in patients with diffuse large B-cell lymphoma at the population level in the United States
Association of CAR-T approval on outcomes in patients with diffuse large B-cell lymphoma at the population level in the United States Open
While the advent of chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of relapsed or refractory DLBCL, it is unclear how survival has changed at the population level following its approval. Herein, we perfor…
View article: A comparative analysis of transformed indolent lymphomas and de novo diffuse large B-cell lymphoma: a population-based cohort study
A comparative analysis of transformed indolent lymphomas and de novo diffuse large B-cell lymphoma: a population-based cohort study Open
View article: Association of Hospitalist Care and Outcomes for Patients Electively Admitted for Chemotherapy
Association of Hospitalist Care and Outcomes for Patients Electively Admitted for Chemotherapy Open
Introduction Patients with hematologic malignancies frequently receive elective anticancer therapy as inpatients. The impact of introducing hospitalists on quality outcomes in this subset of patients is unknown. Methods Patients with leuke…
View article: Survival of patients with transformed follicular lymphoma in the United States: a multiple cohort study
Survival of patients with transformed follicular lymphoma in the United States: a multiple cohort study Open
View article: Reframing the Conversation Around Physician Burnout and Moral Injury: “We’re Not Suffering From a Yoga Deficiency”
Reframing the Conversation Around Physician Burnout and Moral Injury: “We’re Not Suffering From a Yoga Deficiency” Open
View article: Partnerships to Care for Our Patients and Communities During COVID-19
Partnerships to Care for Our Patients and Communities During COVID-19 Open
The Coronavirus disease 2019 (COVID-19) pandemic forced not only rapid changes in how clinical care and educational programs are delivered but also challenged academic medical centers (AMCs) like never before. The pandemic made clear the n…
View article: Racial disparities in the survival of patients with indolent <scp>non‐Hodgkin</scp> lymphomas in the United States
Racial disparities in the survival of patients with indolent <span>non‐Hodgkin</span> lymphomas in the United States Open
There is a paucity of data regarding racial disparities in the survival of patients with indolent non‐Hodgkin lymphomas (iNHL) in the contemporary time‐period. Hence, we sought to determine whether racial disparities exist in the survival …
View article: Survival of patients with marginal zone lymphoma in the <scp>United States:</scp> A population‐based cohort study (2000 to 2017)
Survival of patients with marginal zone lymphoma in the <span>United States:</span> A population‐based cohort study (2000 to 2017) Open
Marginal zone lymphoma (MZL) is an indolent Non-Hodgkin lymphoma (NHL) that originates from the marginal zone of B-cell follicles. Treatment of MZL has advanced over the past two decades. In the early 2000s, the use of rituximab for MZL im…
View article: COVID-19 Severity and Outcomes in Patients With Cancer: A Matched Cohort Study
COVID-19 Severity and Outcomes in Patients With Cancer: A Matched Cohort Study Open
PURPOSE SARS-CoV-2 (COVID-19) is a systemic infection. Patients with cancer are immunocompromised and may be vulnerable to COVID-related morbidity and mortality. The objectives of this study were to determine if patients with cancer have w…
View article: Recent survival trends in diffuse large B‐cell lymphoma––<i>Have we made any progress beyond rituximab?</i>
Recent survival trends in diffuse large B‐cell lymphoma––<i>Have we made any progress beyond rituximab?</i> Open
Background Population‐based studies previously showed an improvement in overall survival (OS) for patients with diffuse large B‐cell lymphoma (DLBCL) who received chemoimmunotherapy with rituximab. However, there is limited data (especiall…
View article: Recurrent Complement-Mediated Thrombotic Microangiopathy in a Patient with Systemic Lupus Erythematosus
Recurrent Complement-Mediated Thrombotic Microangiopathy in a Patient with Systemic Lupus Erythematosus Open
View article: Racial Differences in Utilization of Hematopoietic Cell Transplantation for Lymphoma in the United States
Racial Differences in Utilization of Hematopoietic Cell Transplantation for Lymphoma in the United States Open
IntroductionRacial disparities have been documented in hematopoietic cell transplantation (HCT), a complex and expensive therapeutic modality for hematologic malignancies. Prior work suggests that racial minorities in the US have lower rat…
View article: Trends in postrelapse survival in classic Hodgkin lymphoma patients after experiencing therapy failure following auto-HCT
Trends in postrelapse survival in classic Hodgkin lymphoma patients after experiencing therapy failure following auto-HCT Open
Key Points PR-OS of cHL patients has improved in recent years, likely due to incorporation of novel therapies and more effective use of allo-HCT. Future research should focus on earlier integration of novel therapies for patients with refr…
View article: Postrelapse survival in diffuse large B-cell lymphoma after therapy failure following autologous transplantation
Postrelapse survival in diffuse large B-cell lymphoma after therapy failure following autologous transplantation Open
Outcomes for diffuse large B-cell lymphoma (DLBCL) patients relapsing after autologous hematopoietic cell transplantation (auto-HCT) have been historically poor. We studied outcomes of such patients using data from 4 transplantation center…
View article: Post-Relapse Survival in Diffuse Large B-Cell Lymphoma (DLBCL) Patients after Experiencing Therapy Failure Following Autologous Hematopoietic Cell Transplantation (auto-HCT)
Post-Relapse Survival in Diffuse Large B-Cell Lymphoma (DLBCL) Patients after Experiencing Therapy Failure Following Autologous Hematopoietic Cell Transplantation (auto-HCT) Open
IntroductionThe outcomes for DLBCL patients who relapse following auto-HCT have been historically poor. Using data from four transplant centers, we studied the outcomes of DLBCL patients who relapsed following auto-HCT and evaluated whethe…
View article: Detection of toxigenic Clostridium difficile colonization in patients admitted to the hospital for chemotherapy or haematopoietic cell transplantation
Detection of toxigenic Clostridium difficile colonization in patients admitted to the hospital for chemotherapy or haematopoietic cell transplantation Open
Increasing evidence suggests that asymptomatic carriers are an important source of healthcare-associated Clostridium difficile infection. However, it is not known which test for the detection of C. difficile colonization is most sensitive …
View article: BRAF V600E expression in histiocytic sarcoma associated with splenic marginal zone lymphoma: a case report
BRAF V600E expression in histiocytic sarcoma associated with splenic marginal zone lymphoma: a case report Open
Our case illustrates the aggressive nature of histiocytic sarcoma, and provides rare evidence that histiocytic sarcoma associated with indolent lymphomas may harbor the BRAF V600E mutation. Further research is needed to clarify …
View article: Acute Systolic Heart Failure Associated with Complement-Mediated Hemolytic Uremic Syndrome
Acute Systolic Heart Failure Associated with Complement-Mediated Hemolytic Uremic Syndrome Open
Complement-mediated hemolytic uremic syndrome (otherwise known as atypical HUS) is a rare disorder of uncontrolled complement activation that may be associated with heart failure. We report the case of a 49-year-old female with no history …