Simon C. Ling
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View article: Insights and outcomes of day-case percutaneous nephrolithotomy: results of a systematic review and single-arm meta-analysis
Insights and outcomes of day-case percutaneous nephrolithotomy: results of a systematic review and single-arm meta-analysis Open
Background: Traditionally performed as an inpatient procedure, day-case or ambulatory percutaneous nephrolithotomy (PCNL) has emerged in recent years as a promising alternative offering the potential to reduce hospital admissions and healt…
View article: Ambulatory percutaneous nephrolithotomy for staghorn calculi: a systematic review
Ambulatory percutaneous nephrolithotomy for staghorn calculi: a systematic review Open
View article: Safe Endoscopic Treatment for a Bleeding Infant With Multifocal Lymphangioendotheliomatosis and Thrombocytopenia (MLT)
Safe Endoscopic Treatment for a Bleeding Infant With Multifocal Lymphangioendotheliomatosis and Thrombocytopenia (MLT) Open
We present the case of a 3-week-old girl with multiple cutaneous vascular lesions, melena, hematemesis, severe anemia (hemoglobin 4.4 g/dL), and thrombocytopenia (72 × 10 3 /µL), with clinical features consistent with multifocal lymphangio…
View article: Adverse fetal and perinatal outcomes associated with Zika virus infection during pregnancy: an individual participant data meta-analysis
Adverse fetal and perinatal outcomes associated with Zika virus infection during pregnancy: an individual participant data meta-analysis Open
View article: Global, regional, and national burden of chronic kidney disease, 1990-2021: a systematic analysis for the global burden of disease study 2021
Global, regional, and national burden of chronic kidney disease, 1990-2021: a systematic analysis for the global burden of disease study 2021 Open
Background Chronic kidney disease (CKD) continues to represent a significant public health concern, with both prevalence and incidence rates on the rise globally. Therefore, the study employed the Global Burden of Disease (GBD) database to…
View article: Children with autoimmune hepatitis receiving standard-of-care therapy demonstrate long-term obesity and linear growth delay
Children with autoimmune hepatitis receiving standard-of-care therapy demonstrate long-term obesity and linear growth delay Open
Background: Standard-of-care therapy in children with autoimmune hepatitis (AIH) includes induction with prednisone 1–2 mg/kg daily with gradual weaning of the dose. We aimed to test the hypothesis that children with AIH receiving standard…
View article: Statin Use Is Associated With Protection Against Acute Cholangitis in Patients With Primary Sclerosing Cholangitis: A Multicenter Retrospective Cohort Study
Statin Use Is Associated With Protection Against Acute Cholangitis in Patients With Primary Sclerosing Cholangitis: A Multicenter Retrospective Cohort Study Open
INTRODUCTION: Patients with primary sclerosing cholangitis (PSC) are at increased risk of acute cholangitis. The epidemiological risks of cholangitis are poorly studied despite the high morbidity associated with this infection. The aim of …
View article: Impact of Blood Vessel Implantation on Quality of Life With Cancer Patients: A Focused Analysis
Impact of Blood Vessel Implantation on Quality of Life With Cancer Patients: A Focused Analysis Open
Background: Breast cancer patients often undergo artificial vascular implantation for long‐term intravenous therapies, which can significantly impact their quality of life (QoL). While vascular access is critical for treatment, the relatio…
View article: A Case of Rare Fourth Branchial Arch Anomaly: Presentation and Surgical Management
A Case of Rare Fourth Branchial Arch Anomaly: Presentation and Surgical Management Open
This report presents a case of a six-year-old male patient with recurrent left-sided neck abscesses who presented four times over a span of two years. At each presentation, the child had developed left-sided neck swelling, pain, and fevers…
View article: Autoimmune hepatitis: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunisation safety data
Autoimmune hepatitis: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunisation safety data Open
View article: A305 ANONYMOUS LIVING LIVER DONATION IMPROVES ACCESS FOR MEDICALLY UNDERSERVED CHILDREN IN NEED OF LIVER TRANSPLANTATION
A305 ANONYMOUS LIVING LIVER DONATION IMPROVES ACCESS FOR MEDICALLY UNDERSERVED CHILDREN IN NEED OF LIVER TRANSPLANTATION Open
Background Since our first pediatric anonymous non-directed live donor liver transplant (A-LDLT) performed in April 2005, 62 children have undergone live donor liver transplant (LDLT) with an anonymous non-directed graft. Anon-LDLT organs …
View article: Cystic fibrosis screening, evaluation, and management of hepatobiliary disease consensus recommendations
Cystic fibrosis screening, evaluation, and management of hepatobiliary disease consensus recommendations Open
Cystic fibrosis (CF) may cause a spectrum of hepatobiliary complications, including portal hypertension, multilobular cirrhosis, and liver failure. Current guidelines on the detection and monitoring of hepatobiliary complications in CF wer…
View article: Severe acute hepatitis of unknown etiology in a large cohort of children
Severe acute hepatitis of unknown etiology in a large cohort of children Open
Background: We evaluated the proportion, clinical features, and outcomes of previously healthy children presenting to a large Canadian quaternary pediatric center with severe acute hepatitis of unknown etiology. Methods: All patients with …
View article: Successful Transjugular Portosystemic Shunt Treatment of Pediatric Sinusoidal Obstruction: Case Report and Review of Literature
Successful Transjugular Portosystemic Shunt Treatment of Pediatric Sinusoidal Obstruction: Case Report and Review of Literature Open
Background: In adults with medically refractory sinusoidal obstruction syndrome (SOS), a transjugular intrahepatic portosystemic shunt (TIPS) has been used successfully to improve portal hypertension and symptoms such as ascites. There is …
View article: Heterogeneous liver on research ultrasound identifies children with cystic fibrosis at high risk of advanced liver disease
Heterogeneous liver on research ultrasound identifies children with cystic fibrosis at high risk of advanced liver disease Open
View article: A262 NEONATAL ACUTE LIVER FAILURE DUE TO PRESUMED GESTATIONAL ALLOIMMUNE LIVER DISEASE - A CASE REPORT
A262 NEONATAL ACUTE LIVER FAILURE DUE TO PRESUMED GESTATIONAL ALLOIMMUNE LIVER DISEASE - A CASE REPORT Open
Background Neonatal acute liver failure (NALF) is a rare disease that is distinct from acute liver failure seen in older children and adults. Gestational alloimmune liver disease (GALD) is the most frequent cause, is initiated in utero by …
View article: Findings in percutaneous trans-hepatic cholecysto-cholangiography in neonates and infants presenting with conjugated hyperbilirubinemia: emphasis on differential diagnosis and cholangiographic patterns
Findings in percutaneous trans-hepatic cholecysto-cholangiography in neonates and infants presenting with conjugated hyperbilirubinemia: emphasis on differential diagnosis and cholangiographic patterns Open
Background Biliary atresia (BA) is one of the causes of conjugated hyperbilirubinemia in infants which if untreated leads to end-stage liver disease and death. Percutaneous Trans-hepatic Cholecysto-Cholangiography (PTCC) is a minimally inv…
View article: Health‐related Quality of Life in a Prospective Study of Ultrasound to Detect Cystic Fibrosis–related Liver Disease in Children
Health‐related Quality of Life in a Prospective Study of Ultrasound to Detect Cystic Fibrosis–related Liver Disease in Children Open
Objectives: Cystic fibrosis liver disease (CFLD) begins early in life. Symptoms may be vague, mild, or nonexistent. Progressive liver injury may be associated with decrements in patient health before liver disease is clinically apparent. W…
View article: MRI Phase-Contrast Blood Flow in Fasting Pediatric Patients with Fontan Circulation Correlates with Exercise Capacity
MRI Phase-Contrast Blood Flow in Fasting Pediatric Patients with Fontan Circulation Correlates with Exercise Capacity Open
Reference ranges are provided for regional systemic blood flow derived by using MRI in fasting pediatric patients with Fontan circulation, who had lower systemic blood flow compared with healthy volunteers. Lower fasting Fontan blood flow …
View article: Non-invasive test of liver fibrosis for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Non-invasive test of liver fibrosis for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis Open
This protocol for a Cochrane Review is out of date. The authors have abandoned it.
View article: Magnetic resonance imaging, computer tomography scan, and oesophagography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Magnetic resonance imaging, computer tomography scan, and oesophagography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis Open
This protocol for a Cochrane Review is out of date. The authors have abandoned it.
View article: Transient ultrasound elastography and magnetic resonance elastography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Transient ultrasound elastography and magnetic resonance elastography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis Open
This protocol for a Cochrane Review is out of date. The authors have abandoned it.
View article: 211: Heterogeneous ultrasound predicts high risk for the development of advanced liver disease in CF children: Final results of PUSH study
211: Heterogeneous ultrasound predicts high risk for the development of advanced liver disease in CF children: Final results of PUSH study Open
View article: Table of Contents
Table of Contents Open
View article: Practical Consideration for Drug Monitoring of Tacrolimus in Liver Transplantation Recipients with SARS‐CoV‐2 Infection
Practical Consideration for Drug Monitoring of Tacrolimus in Liver Transplantation Recipients with SARS‐CoV‐2 Infection Open
Joshi, Tejas M.D; Rana, Abbas M.D.; Vierling, John M. M.D.; Kanwal, Fasiha M.D.; Goss, John A. M.D.; Cholankeril, George M.D., M.S.E.C.R. Author Information
View article: Chronic Hepatitis Is Common and Often Untreated Among Children with Hepatitis B Infection in the United States and Canada
Chronic Hepatitis Is Common and Often Untreated Among Children with Hepatitis B Infection in the United States and Canada Open
View article: Association Between Transient Elastography and Controlled Attenuated Parameter and Liver Ultrasound in Children With Cystic Fibrosis
Association Between Transient Elastography and Controlled Attenuated Parameter and Liver Ultrasound in Children With Cystic Fibrosis Open
Methods to identify children with cystic fibrosis (CF) at risk for development of advanced liver disease are lacking. We aim to determine the association between liver stiffness measurement (LSM) by vibration‐controlled transient elastogra…
View article: Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance
Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance Open
PURPOSE Constitutional mismatch repair deficiency syndrome (CMMRD) is a lethal cancer predisposition syndrome characterized by early-onset synchronous and metachronous multiorgan tumors. We designed a surveillance protocol for early tumor …
View article: Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Children With Chronic HCV: Part 2 of the DORA Study
Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Children With Chronic HCV: Part 2 of the DORA Study Open
Background and Aims Glecaprevir/pibrentasvir (GLE/PIB) has shown high efficacy and safety in chronic HCV‐infected adults and adolescents; data in children were limited. DORA part 2 is a phase 2/3, nonrandomized, open‐label study evaluating…
View article: Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver
Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver Open
Studies of human hepatitis B virus (HBV) immune pathogenesis are hampered by limited access to liver tissues and technologies for detailed analyses. Here, utilizing imaging mass cytometry (IMC) to simultaneously detect 30 immune, viral, an…