John Lorber
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View article: Spina bifida--a vanishing nightmare?
Spina bifida--a vanishing nightmare? Open
Detailed analysis is presented on the dramatic decline in spina bifida births and other congenital central nervous system defects in the past 12 years, in both Sheffield and the rest of Great Britain. In Sheffield, there was an average of …
View article: <b>Points</b> : Family history of congenital hydrocephalus
<b>Points</b> : Family history of congenital hydrocephalus Open
September, p 591) confirmed brain death in the usual way before resuscitation was finally abandoned after four hours.The usual tests of brain death are tests of brain stem function.These tests should be preceded by essential preconditions …
View article: The family history of uncomplicated congenital hydrocephalus: an epidemiological study based on 270 probands.
The family history of uncomplicated congenital hydrocephalus: an epidemiological study based on 270 probands. Open
A longitudinal study was carried out on the family history of 270 babies with uncomplicated congenital hydrocephalus. They had 453 siblings of whom five (11.1/1000) had congenital hydrocephalus and nine (19.9/1000) neural tube defects. The…
View article: Results of selective treatment of spina bifida cystica.
Results of selective treatment of spina bifida cystica. Open
The results of selective treatment in 120 infants with open spina bifida, admitted between May 1971 and December 1976, were prospectively studied. Seventy-one infants had adverse criteria at birth and were not treated. They all died, more …
View article: Nonaccidental poisoning: the elusive diagnosis.
Nonaccidental poisoning: the elusive diagnosis. Open
Although nonaccidental poisoning in childhood is now more often recognised, it is still difficult to establish a diagnosis despite correct investigative procedures. In 1978 we were unable, initially, to establish the cause of intermittent …
View article: Acute infantile thrombocytosis and vitamin K deficiency associated with intracranial haemorrhage.
Acute infantile thrombocytosis and vitamin K deficiency associated with intracranial haemorrhage. Open
A 5-week-old breast-fed girl presented unconscious and convulsing with heavily blood-stained CSF under increased pressure. This was associated with oozing from venepuncture sites, a grossly prolonged prothrombin time, and a raised platelet…
View article: Ethical problems in the management of myelomeningocele and hydrocephalus. The Milroy Lecture 1975.
Ethical problems in the management of myelomeningocele and hydrocephalus. The Milroy Lecture 1975. Open
Within the last generation the application of major advances in drug therapy, intensive care, transfusion techniques, surgery, anaesthesia, and radiotherapy, together with a vast expansion of knowledge due to increased investigative facili…
View article: Isosorbide in treatment of infantile hydrocephalus.
Isosorbide in treatment of infantile hydrocephalus. Open
This paper reports the experiences of the second clinical trial in the use of isosorbide in the treatment of 34 selected cases of infantile hydrocephalus of all types. Subject to careful biochemical monitoring of serum electrolyte, urea, a…
View article: Posthaemorrhagic hydrocephalus: Diagnosis, differential diagnosis, treatment, and long-term results
Posthaemorrhagic hydrocephalus: Diagnosis, differential diagnosis, treatment, and long-term results Open
The clinical features, investigations, and results of treatment are described in a series of 47 infants with posthaemorrhagic hydrocephalus. 7 were unfit for treatment; 3 had medical (isosorbide) treatment alone, 2 of whom made a good reco…
View article: Early Results of Selective Treatment of Spina Bifida Cyctica
Early Results of Selective Treatment of Spina Bifida Cyctica Open
The results of a policy of "selection" in treating infants with spina bifida cystica over 21 months are presented. Of 37 newborn infants referred on the first day of life 25 were not treated because of the severity of their condition, as d…
View article: Spina Bifida Cystica: Results of Treatment of 270 Consecutive Cases with Criteria for Selection for the Future
Spina Bifida Cystica: Results of Treatment of 270 Consecutive Cases with Criteria for Selection for the Future Open
The disappointing results of treatment in 270 consecutive unselected cases of spina bifida admitted during a 27-month period are detailed. Massive effort has led to much avoidable suffering at an exorbitant cost in manpower and money. This…
View article: Treatment of Ventriculitis with Gentamicin and Cloxacillin in Infants Born with Spina Bifida
Treatment of Ventriculitis with Gentamicin and Cloxacillin in Infants Born with Spina Bifida Open
Of 783 newborn infants with spina bifida cystica and cranium bifidum treated in the 6 years to December 1966, 11% died of ventriculitis. 24% of all deaths were due to this cause. Experience with treatment of ventriculitis with 2 of the ant…
View article: A patient with 45,XX,Gminus-46,XX,Gr mosaicism.
A patient with 45,XX,Gminus-46,XX,Gr mosaicism. Open
This is a brief report on a patient with physical and mental maldevelopment who was shown to have a chromosome abnormality of an unusual type affecting the G (21-22) group.Case History She was an only child born when her mother was 26 and …
View article: Long-term prognosis of subdural effusions in infancy.
Long-term prognosis of subdural effusions in infancy. Open
surgical palliation in tricuspid atresia, pulmonary atresia with intact ventricular septum, and mitral atresia.The place of atrial septostomy in the treatment of total anomalous pulmonary venous connexion was not established.
View article: Incidence and treatment of post-meningitic hydrocephalus in the newborn.
Incidence and treatment of post-meningitic hydrocephalus in the newborn. Open
Neonatal meningitis remains an extremely difficult diagnostic and therapeutic problem.In spite of the large number of antibiotics which are now at our disposal, the mortality remains high and few survivors escape without sequelae.In recent…