John P. Bennett
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View article: Genomic prostate score and treatment selection in favourable intermediate‐risk prostate cancer
Genomic prostate score and treatment selection in favourable intermediate‐risk prostate cancer Open
Objective To assess the factors associated with the use of active surveillance (AS) in NCCN favourable intermediate‐risk (FIR) prostate cancer (PCa) patients who received the 17‐gene Genomic Prostate Score (GPS) assay. Material and Methods…
View article: Validation of a breast cancer assay for radiotherapy omission: an individual participant data meta-analysis
Validation of a breast cancer assay for radiotherapy omission: an individual participant data meta-analysis Open
Background There are currently no molecular tests to identify individual breast cancers where radiotherapy (RT) offers no benefit. Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) is a 16-gene molecular signature developed t…
View article: Validation of Prognostic Value of Profile for Omission of Adjuvant Radiotherapy (Polar) in the Scottish Conservation Trial in Early Breast Cancer
Validation of Prognostic Value of Profile for Omission of Adjuvant Radiotherapy (Polar) in the Scottish Conservation Trial in Early Breast Cancer Open
View article: The 17-Gene Genomic Prostate Score Test Is Prognostic for Outcomes After Primary External Beam Radiation Therapy in Men With Clinically Localized Prostate Cancer
The 17-Gene Genomic Prostate Score Test Is Prognostic for Outcomes After Primary External Beam Radiation Therapy in Men With Clinically Localized Prostate Cancer Open
Among men treated with EBRT, the GPS assay is a strong, independent prognostic indicator of time to BCF, DM, and PCD, and performs similarly in Black and non-Black men.
View article: The 17-gene Genomic Prostate Score assay as a predictor of biochemical recurrence in men with intermediate and high-risk prostate cancer
The 17-gene Genomic Prostate Score assay as a predictor of biochemical recurrence in men with intermediate and high-risk prostate cancer Open
The validated 17-gene Oncotype DX Genomic Prostate Score® (GPS™) assay risk-stratifies prostate-cancer patients with localized disease. The assay has primarily been utilized in lower risk patients deciding between active surveillance versu…
View article: Association of the 12-Gene Breast DCIS Score® Assay With Local Recurrence in Patients With Ductal Carcinoma In Situ Treated on Accelerated Partial Breast Radiotherapy Protocols
Association of the 12-Gene Breast DCIS Score® Assay With Local Recurrence in Patients With Ductal Carcinoma In Situ Treated on Accelerated Partial Breast Radiotherapy Protocols Open
Background The following analysis explores clinicopathologic factors and the 12-gene Breast DCIS Score test result in order to better define an appropriate DCIS (ductal carcinoma in situ ) population eligible for APBI (accelerated partial …
View article: Association of the 12-gene Breast DCIS Score® assay with local recurrence in patients with ductal carcinoma in situ treated on accelerated partial breast radiotherapy protocols
Association of the 12-gene Breast DCIS Score® assay with local recurrence in patients with ductal carcinoma in situ treated on accelerated partial breast radiotherapy protocols Open
Background The following analysis explores clinicopathologic factors and the 12-gene Breast DCIS Score test result in order to better define an appropriate DCIS (ductal carcinoma in situ) population eligible for APBI (accelerated partial b…
View article: A Comparison of Predicted Ipsilateral Tumor Recurrence Risks in Patients With Ductal Carcinoma in Situ of the Breast After Breast-Conserving Surgery by Breast Radiation Oncologists, the Van Nuys Prognostic Index, the Memorial Sloan Kettering Cancer Center DCIS Nomogram, and the 12-Gene DCIS Score Assay
A Comparison of Predicted Ipsilateral Tumor Recurrence Risks in Patients With Ductal Carcinoma in Situ of the Breast After Breast-Conserving Surgery by Breast Radiation Oncologists, the Van Nuys Prognostic Index, the Memorial Sloan Kettering Cancer Center DCIS Nomogram, and the 12-Gene DCIS Score Assay Open
Purpose: To compare ipsilateral breast event (IBE) risks in patients with ductal carcinoma in situ of the breast (DCIS) post-lumpectomy, as estimated by breast radiation oncologists, the Van Nuys Prognostic Index, the Memorial Sloan Ketter…
View article: 47. Long Term Outcomes of Pulse-taper Corticosteroid Therapy (PCT) for Refractory Non-HIV Cryptococcal Meningoencephalitis
47. Long Term Outcomes of Pulse-taper Corticosteroid Therapy (PCT) for Refractory Non-HIV Cryptococcal Meningoencephalitis Open
Background Cryptococcal meningoencephalitis (CM) is a major cause of mortality in HIV/AIDS, transplant recipients and previously healthy individuals. In the latter, a post-infectious inflammatory response syndrome (PIIRS) is associated wit…
View article: Liquid biopsy mutation panel for non-small cell lung cancer: analytical validation and clinical concordance
Liquid biopsy mutation panel for non-small cell lung cancer: analytical validation and clinical concordance Open
View article: Prostate Cancer: Localized: Active Surveillance I (MP23)
Prostate Cancer: Localized: Active Surveillance I (MP23) Open
You have accessJournal of UrologyProstate Cancer: Localized: Active Surveillance I (MP23)1 Apr 2020Prostate Cancer: Localized: Active Surveillance I (MP23) View All Author Informationhttps://doi.org/10.1097/JU.0000000000000856AboutPDF Tool…
View article: MP23-07 THE 17-GENE RT-PCR PROSTATE ASSAY: CLINICAL EXPERIENCE IN 33,000 PATIENTS WITH CLINICALLY LOW-RISK PROSTATE CANCER
MP23-07 THE 17-GENE RT-PCR PROSTATE ASSAY: CLINICAL EXPERIENCE IN 33,000 PATIENTS WITH CLINICALLY LOW-RISK PROSTATE CANCER Open
You have accessJournal of UrologyProstate Cancer: Localized: Active Surveillance I (MP23)1 Apr 2020MP23-07 THE 17-GENE RT-PCR PROSTATE ASSAY: CLINICAL EXPERIENCE IN 33,000 PATIENTS WITH CLINICALLY LOW-RISK PROSTATE CANCER John Bennett, Tam…
View article: Young-Onset Colon Cancer and Recurrence Risk by Gene Expression
Young-Onset Colon Cancer and Recurrence Risk by Gene Expression Open
The incidence and mortality from colorectal cancer in younger adults (younger than 55 years) is increasing. We reviewed the complete database of a gene-expression test, Oncotype DX Colon Recurrence Score test, to determine age-related diff…
View article: A 17-gene Panel for Prediction of Adverse Prostate Cancer Pathologic Features: Prospective Clinical Validation and Utility
A 17-gene Panel for Prediction of Adverse Prostate Cancer Pathologic Features: Prospective Clinical Validation and Utility Open
In this real-world multi-institutional study, the GPS assay was prospectively confirmed as an independent predictor of AP at surgery. GPS testing was associated with reduced patient decisional conflict.
View article: 147P Clinical testing of ctDNA from NSCLC patients using A 17-gene liquid biopsy mutation panel
147P Clinical testing of ctDNA from NSCLC patients using A 17-gene liquid biopsy mutation panel Open
View article: MP35-14 A 17-GENE ASSAY DRIVES HIGH ACTIVE SURVEILLANCE PERSISTENCE IN CLINICALLY LOW-RISK PROSTATE CANCER: 1 YEAR RESULTS FROM A 1,200 PATIENT PROSPECTIVE OBSERVATIONAL TRIAL
MP35-14 A 17-GENE ASSAY DRIVES HIGH ACTIVE SURVEILLANCE PERSISTENCE IN CLINICALLY LOW-RISK PROSTATE CANCER: 1 YEAR RESULTS FROM A 1,200 PATIENT PROSPECTIVE OBSERVATIONAL TRIAL Open
You have accessJournal of UrologyProstate Cancer: Markers I1 Apr 2018MP35-14 A 17-GENE ASSAY DRIVES HIGH ACTIVE SURVEILLANCE PERSISTENCE IN CLINICALLY LOW-RISK PROSTATE CANCER: 1 YEAR RESULTS FROM A 1,200 PATIENT PROSPECTIVE OBSERVATIONAL …
View article: MP28-11 IMPACT OF THE 17-GENE PANEL ON ACTIVE SURVEILLANCE PERSISTENCE IN CONTEMPORARY UROLOGIC PRACTICES: AN INTERIM ANALYSIS IN AN OBSERVATIONAL COHORT
MP28-11 IMPACT OF THE 17-GENE PANEL ON ACTIVE SURVEILLANCE PERSISTENCE IN CONTEMPORARY UROLOGIC PRACTICES: AN INTERIM ANALYSIS IN AN OBSERVATIONAL COHORT Open
You have accessJournal of UrologyProstate Cancer: Markers I1 Apr 2017MP28-11 IMPACT OF THE 17-GENE PANEL ON ACTIVE SURVEILLANCE PERSISTENCE IN CONTEMPORARY UROLOGIC PRACTICES: AN INTERIM ANALYSIS IN AN OBSERVATIONAL COHORT Gregg Eure, Raym…
View article: The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa
The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa Open
Among HIV-infected individuals, greater activity of the kynurenine pathway of tryptophan catabolism, as evidenced by higher levels of plasma KT ratio, was associated with lower occurrence of KS. Some consequences of immune activation in HI…