John P. Cannon
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View article: Development of an open-source tool for risk assessment in pulmonary endarterectomy
Development of an open-source tool for risk assessment in pulmonary endarterectomy Open
Background Risk prediction tools are routinely utilised in cardiothoracic surgery but have not been developed for pulmonary endarterectomy (PEA). There is no data on whether patients undergoing PEA may benefit from a tailored risk modellin…
View article: PTH-074 A case series of patients given successive rescue therapy for steroid refractory severe ulcerative colitis
PTH-074 A case series of patients given successive rescue therapy for steroid refractory severe ulcerative colitis Open
Introduction Following intravenous steroid use, salvage therapy for acute, severe Ulcerative Colitis consists of infliximab or ciclosporin. Conventional escalation therapy beyond this comprises referral to the surgeons for colectomy and th…
View article: A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains
A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains Open
The gut microbiome of animals consists of diverse microorganisms that include both prokaryotes and eukaryotes. Complex interactions occur among these inhabitants, as well as with the immune system of the host, and profoundly influence the …
View article: Isolation and Characterization of a Shewanella Phage–Host System from the Gut of the Tunicate, Ciona intestinalis
Isolation and Characterization of a Shewanella Phage–Host System from the Gut of the Tunicate, Ciona intestinalis Open
Outnumbering all other biological entities on earth, bacteriophages (phages) play critical roles in structuring microbial communities through bacterial infection and subsequent lysis, as well as through horizontal gene transfer. While nume…