John Saxton
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View article: The test-retest reliability of the H-Reflex and swaymeter in women aged 30–65 years
The test-retest reliability of the H-Reflex and swaymeter in women aged 30–65 years Open
Background The H-reflex can objectively assess sensorimotor integration relevant to proprioception and postural control. Chemotherapy-induced peripheral neuropathy (CIPN) is a common and potentially dose-limiting side effect among breast c…
View article: Co-development of a programme to improve physical activity support for women after breast cancer treatment: a pre-protocol for PURE-EX
Co-development of a programme to improve physical activity support for women after breast cancer treatment: a pre-protocol for PURE-EX Open
Background Breast cancer and its treatment can have long-term adverse effects on physical and mental health. Evidence-based guidelines recommend that healthcare professionals (HCPs) advise women with breast cancer to engage in physical ac…
View article: Nutrition Modulation of Cardiotoxicity in Breast Cancer: A Scoping Review
Nutrition Modulation of Cardiotoxicity in Breast Cancer: A Scoping Review Open
Background/Objectives: Advancements in breast cancer therapeutics, such as anthracyclines, are improving cancer survival rates but can have side effects that limit their use. Cardiotoxicity, defined as damage to the heart caused by cancer …
View article: The sustainability of exercise following colorectal surgery: A qualitative study of participants in the PREPARE-ABC trial
The sustainability of exercise following colorectal surgery: A qualitative study of participants in the PREPARE-ABC trial Open
Objective This study aimed to explore perceptions regarding the sustainability of exercise following participation in a pre- and post-colorectal surgery exercise intervention trial (PREPARE-ABC). Design Qualitative interview study. Data we…
View article: 73 Green2Gold: Creating and testing ‘Team GB Family Activity Trails’ for improving wellbeing and outdoor physical activity engagement in the East Riding of Yorkshire, England
73 Green2Gold: Creating and testing ‘Team GB Family Activity Trails’ for improving wellbeing and outdoor physical activity engagement in the East Riding of Yorkshire, England Open
Purpose Systematic review evidence suggests that undertaking green exercise (GE; Coventry et al., 2021) including walking (Hanson & Jones, 2015) can positively impact health and wellbeing. The ‘Green2Gold’ project collaborated with The Bri…
View article: Green2Gold: Piloting ‘Team GB Family Activity Trails’ as a green exercise project for improving wellbeing and outdoor physical activity engagement in the East Riding of Yorkshire
Green2Gold: Piloting ‘Team GB Family Activity Trails’ as a green exercise project for improving wellbeing and outdoor physical activity engagement in the East Riding of Yorkshire Open
Systematic review evidence suggests that participation in green exercise (GE; Coventry et al., 2021, SSM-Population Health, 16, 100934) including walking (Hanson and Jones, 2015, Brit J Sports Med, 49, 710-715) can positively impact health…
View article: Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic peripheral arterial disease
Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic peripheral arterial disease Open
There is very uncertain evidence that additional exercise therapy after successful lower limb revascularisation may improve absolute maximal walking distance at the end of follow-up compared to standard care. Evidence is also very uncertai…
View article: A group concept mapping and ethnographic study of intensive care rehabilitation culture
A group concept mapping and ethnographic study of intensive care rehabilitation culture Open
Background Early physical activity and physical rehabilitation are advocated in the critical care unit for patients recovering from critical illness. Despite this, there are still many factors associated with implementation of early physic…
View article: The Effect of Menstrual-Cycle Phase on Immune Responses to a 5-km Cycling Time Trial: An Exploratory Study
The Effect of Menstrual-Cycle Phase on Immune Responses to a 5-km Cycling Time Trial: An Exploratory Study Open
Purpose : Exercise has transient effects on the immune system that could influence infection risk and tissue recovery after exercise. Little is known about how the menstrual cycle interacts with the immune responses to acute exercise. This…
View article: Co-designed weight management intervention for women recovering from oestrogen-receptor positive breast cancer
Co-designed weight management intervention for women recovering from oestrogen-receptor positive breast cancer Open
Background Weight gain is commonly observed during and after breast cancer treatment and is associated with poorer survival outcomes, particularly in women with oestrogen receptor-positive (ER +) disease. The aim of this study was to co-de…
View article: Evaluating the feasibility and acceptability of an exercise and behaviour change intervention in socioeconomically deprived patients with peripheral arterial disease: The textpad study protocol
Evaluating the feasibility and acceptability of an exercise and behaviour change intervention in socioeconomically deprived patients with peripheral arterial disease: The textpad study protocol Open
This pilot randomised controlled trial aims to assess the feasibility and acceptability of a 12-week home-based telehealth exercise and behavioural intervention delivered in socioeconomically deprived patients with peripheral artery diseas…
View article: Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of <scp>DNA</scp> damage
Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of <span>DNA</span> damage Open
Epidemiological evidence shows that regular physical activity is associated with reduced risk of primary and recurrent colon cancer. However, the underlying mechanisms of action are poorly understood. We evaluated the effects of stimulatin…
View article: Obesity and low levels of physical activity impact on cardiopulmonary fitness in older men after treatment for prostate cancer
Obesity and low levels of physical activity impact on cardiopulmonary fitness in older men after treatment for prostate cancer Open
The purpose of this study was to compare fitness parameters and cardiovascular disease risk of older and younger men with prostate cancer (PCa) and explore how men's fitness scores compared to normative age values. 83 men were recruited po…
View article: Objectively-assessed physical activity and self-reported activity pacing in adults with multiple sclerosis: A pilot study
Objectively-assessed physical activity and self-reported activity pacing in adults with multiple sclerosis: A pilot study Open
Objective: To examine the association between self-reported activity pacing (a strategy to manage fatigue symptoms) and objectively-measured physical activity behaviours in adults with multiple sclerosis. Design: Single cross-sectional stu…
View article: Effects of additional exercise therapy after a successful vascular intervention for patients with symptomatic peripheral arterial disease
Effects of additional exercise therapy after a successful vascular intervention for patients with symptomatic peripheral arterial disease Open
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To analyse the effects of a supervised exercise programme following successful lower limb revascularisation compared with standard care following lower…
View article: Implementing supportive exercise interventions in the colorectal cancer care pathway: a process evaluation of the PREPARE-ABC randomised controlled trial.
Implementing supportive exercise interventions in the colorectal cancer care pathway: a process evaluation of the PREPARE-ABC randomised controlled trial. Open
Background : A colorectal resection is standard treatment for patients with colorectal cancer (CRC). However, the procedure results in significant post-operative mortality and reduced quality of life. Maximising pre-operative cardiopulmona…
View article: Using qualitative and co-design methods to inform the development of an intervention to support and improve physical activity in childhood cancer survivors: a study protocol for BEing Active after ChildhOod caNcer (BEACON)
Using qualitative and co-design methods to inform the development of an intervention to support and improve physical activity in childhood cancer survivors: a study protocol for BEing Active after ChildhOod caNcer (BEACON) Open
Introduction Childhood cancer survivors (CCSs) treated with cardiotoxic cancer treatments are at increased risk of developing cardiometabolic complications. This risk is further exacerbated by poor health behaviours. In particular, CCSs ar…