J.W. Tierney
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View article: SARS-Cov-2 vaccination strategies in hospitalized recovered COVID-19 patients: a randomized clinical trial (VATICO Trial)
SARS-Cov-2 vaccination strategies in hospitalized recovered COVID-19 patients: a randomized clinical trial (VATICO Trial) Open
View article: Intravascular delivery of an MK2 inhibitory peptide to prevent restenosis after angioplasty
Intravascular delivery of an MK2 inhibitory peptide to prevent restenosis after angioplasty Open
Peripheral artery disease is commonly treated with balloon angioplasty, a procedure involving minimally invasive, transluminal insertion of a catheter to the site of stenosis, where a balloon is inflated to open the blockage, restoring blo…
View article: Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite
Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite Open
The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination co…
View article: Alkali or alkaline earth metal promoted catalyst and a process for methanol synthesis using alkali or alkaline earth metals as promoters
Alkali or alkaline earth metal promoted catalyst and a process for methanol synthesis using alkali or alkaline earth metals as promoters Open
The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a heterogeneous catalyst …
View article: Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite for methanol synthesis
Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite for methanol synthesis Open
The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination co…
View article: Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)
Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO) Open
View article: Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch
Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch Open
Vascular procedures, such as stenting, angioplasty, and bypass grafting, often fail due to intimal hyperplasia (IH), wherein contractile vascular smooth muscle cells (VSMCs) dedifferentiate to synthetic VSMCs, which are highly proliferativ…
View article: Modifying Cell Membranes with Anionic Polymer Amphiphiles Potentiates Intracellular Delivery of Cationic Peptides
Modifying Cell Membranes with Anionic Polymer Amphiphiles Potentiates Intracellular Delivery of Cationic Peptides Open
Rapid, facile, and noncovalent cell membrane modification with alkyl-grafted anionic polymers was sought as an approach to enhance intracellular delivery and bioactivity of cationic peptides. We synthesized a library of acrylic acid-based …
View article: Historic Graves
Historic Graves Open
View article: Genetically Encoded Split-Luciferase Biosensors to Measure Endosome Disruption Rapidly in Live Cells
Genetically Encoded Split-Luciferase Biosensors to Measure Endosome Disruption Rapidly in Live Cells Open
Endosomal escape is a critical step in the intracellular delivery of biomacromolecular drugs, but a quantitative, high-throughput study of endosomal-vesicle disruption remains elusive. We designed two genetically encoded split-luciferase t…
View article: Genetically encoded split luciferase biosensors to measure endosome disruption in real time in live cells
Genetically encoded split luciferase biosensors to measure endosome disruption in real time in live cells Open
Endosomal escape is a critical step in intracellular delivery of biomacromolecular drugs, but quantitative, high throughput study of endosomal vesicle disruption remains elusive. We designed two genetically encoded split luciferase “turn o…
View article: An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles Open
View article: Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration
Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration Open
View article: Polymeric biomaterials for biophotonic applications
Polymeric biomaterials for biophotonic applications Open