Explanipedia

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization (Adv. Sci. 29/2025) Open

Yu‐Jin Kim, Hyeok Kim, Dong‐Hyun Lee, Yeong Hwan Kim, Jae‐Hyun Park , et al. · 2025

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization Open

Yu‐Jin Kim, Hyeok Kim, Dong‐Hyun Lee, Yeong Hwan Kim, Jae‐Hyun Park , et al. · 2025

Despite the promising potential of stromal cell therapy in treating myocardial infarction (MI), its effectiveness is limited by poor cell retention and engraftment in ischemic environments. This study introduces a novel strategy that combi…

Porous Carbon Electrode Made of Biomass DNAs for High-Efficiency Quasi-Solid-State Supercapacitor Open

Samanth Kokkiligadda, Surya Kiran Ampasala, Yeonju Nam, Jeonghun Kim, Suk Ho Bhang , et al. · 2025

Since companies have declared their commitment to operating with 100% renewable energy, developing electrical storage systems using natural eco-friendly resources is in full swing. Efforts to replace existing materials in core electrode ma…

A biospecies-derived genomic DNA hybrid gel electrolyte for electrochemical energy storage Open

Sekhar Babu Mitta, Jeonghun Kim, Harpalsinh H. Rana, Samanth Kokkiligadda, Yong Taik Lim , et al. · 2024

Intrinsic impediments, namely weak mechanical strength, low ionic conductivity, low electrochemical performance, and stability have largely inhibited beyond practical applications of hydrogels in electronic devices and remains as a signifi…

Photocuring 3D printing technology as an advanced tool for promoting angiogenesis in hypoxia-related diseases Open

Sangyoon Lee, Huynh Dai Phuc, Soong Ho Um, Rosaire Mongrain, Jeong‐Kee Yoon , et al. · 2024

Three-dimensional (3D) bioprinting has emerged as a promising strategy for fabricating complex tissue analogs with intricate architectures, such as vascular networks. Achieving this necessitates bioink formulations that possess highly prin…

ProLonged Liposomal Delivery of TLR7/8 Agonist for Enhanced Cancer Vaccine Open

Sehui Kim, Yeji Park, Jeonghun Kim, Sohyun Kim, Kyungmin Choi , et al. · 2023

Despite numerous studies on cancer treatment, cancer remains a challenging disease to cure, even after decades of research. In recent years, the cancer vaccine has emerged as a promising approach for cancer treatment, offering few unexpect…

ProLonged Liposomal Delivery of TLR7/8 Agonist for Enhanced Cancer Vaccine Open

Sehui Kim, Yeji Park, Jeong Hun Kim, Sohyun Kim, Kyungmin Choi , et al. · 2023

Despite numerous studies on cancer treatment, cancer remains a challenging disease to cure, even after decades of research. In recent years, cancer vaccine has emerged as a promising approach for cancer treatment, offering few unexpected s…

Cytotoxic Effect and Mechanism of Nano-Sized Polystyrene Degraded by Rhodococcus Ruber C208 Open

Jiin Eom, Arslan Sarwar, Gwang‐Bum Im, Sungwon Kim, Linh Thanh Nguyen , et al. · 2023

Silica-Capped and Gold-Decorated Silica Nanoparticles for Enhancing Effect of Gold Nanoparticle-Based Photothermal Therapy Open

Jung Hwan Park, Hyun‐Seok Choe, Sungwon Kim, Gwang‐Bum Im, Soong Ho Um , et al. · 2022

Flexible Supercapacitor with a Pure DNA Gel Electrolyte Open

Sekhar Babu Mitta, Harpalsinh H. Rana, Jeonghun Kim, Ho Seok Park, Soong Ho Um · 2022

Due to the demand for next‐generation green wearable and flexible energy storage devices, gel‐based electrolytes are attracting much attention as a key part of this system, but existing materials are problematic because of their low perfor…

Effects of glutaric anhydride functionalization on filler-free benzoxazine/epoxy copolymers with shape memory and self-healing properties under near-infrared light actuation Open

Lunjakorn Amornkitbamrung, Sitanan Leungpuangkaew, Tewarak Panklang, Chanchira Jubsilp, Sanong Ekgasit , et al. · 2022

Protein‐Encoding Free‐Standing RNA Hydrogel for Sub‐Compartmentalized Translation Open

So Yeon Ahn, Jeonghun Kim, Srivithya Vellampatti, Sung Yong Oh, Yong Taik Lim , et al. · 2022

RNA can self‐fold into complex structures that can serve as major biological regulators in protein synthesis and in catalysis. Due to the abundance of structural primitives and functional diversity, RNA has been utilized for designing natu…

Anti-senescence ion-delivering nanocarrier for recovering therapeutic properties of long-term-cultured human adipose-derived stem cells Open

Yeong Hwan Kim, Gwang‐Bum Im, Sungwon Kim, Yu-Jin Kim, Taekyung Yu , et al. · 2021

Background Human adipose-derived stem cells (hADSCs) have been used in various fields of tissue engineering because of their promising therapeutic efficacy. However, the stemness of hADSCs cannot be maintained for long durations, and their…

Overcoming Chemoimmunotherapy‐Induced Immunosuppression by Assemblable and Depot Forming Immune Modulating Nanosuspension Open

Seung Mo Jin, Sang Nam Lee, Jung Eun Kim, Yeon Jeong Yoo, Chanyoung Song , et al. · 2021

The deficiency of antigen‐specific T cells and the induction of various treatment‐induced immunosuppressions still limits the clinical benefit of cancer immunotherapy. Although the chemo‐immunotherapy adjuvanted with Toll‐like receptor 7/8…

Bead-Immobilized Multimodal Molecular Beacon-Equipped DNA Machinery for Specific RNA Target Detection: A Prototypical Molecular Nanobiosensor Open

Jeonghun Kim, So Yeon Ahn, Soong Ho Um · 2021

A variety of nanostructured diagnostic tools have been developed for the precise detection of known genetic variants. Molecular beacon systems are very promising tools due to their specific selectivity coupled with relatively lower cost an…

Cover Feature: Short RNA Universal Coding for Topological Transformation Nano‐barcoding Application (ChemBioChem 2/2021) Open

Jeonghun Kim, Je Hun Moon, Soong Ho Um · 2021

Disease diagnosis and prognosis through the detection of genetic biomarkers occupy an important part in molecular biology. Considering the thermodynamics of the strand-displacement reaction, we studied a system that can convert various miR…

Lightwave-reinforced stem cells with enhanced wound healing efficacy Open

Yujin Kim, Hye Ran Jeon, Sung‐Won Kim, Yeong Hwan Kim, Gwang‐Bum Im , et al. · 2021

Comprehensive research has led to significant preclinical outcomes in modified human adipose-derived mesenchymal stem cells (hADSCs). Photobiomodulation (PBM), a technique to enhance the cellular capacity of stem cells, has attracted consi…

DNA Transformations for Diagnosis and Therapy Open

So Yeon Ahn, Jin Liu, Srivithya Vellampatti, Yuzhou Wu, Soong Ho Um · 2020

Due to its unique physical and chemical characteristics, DNA, which is known only as genetic information, has been identified and utilized as a new material at an astonishing rate. The role of DNA has increased dramatically with the advent…

Gold nanoparticle clusters for the investigation of therapeutic efficiency against prostate cancer under near-infrared irradiation Open

Jeonghun Kim, Sang Hun Chun, Lunjakorn Amornkitbamrung, Chanyoung Song, Ji Soo Yuk , et al. · 2020

Gold particles have been widely used in the treatment of prostate cancer due to their unique optical properties, such as their light-heat conversion in response to near-infrared radiation. Due to well-defined synthesis mechanisms and simpl…

Hybrid material of structural DNA with inorganic compound: synthesis, applications, and perspective Open

Seung Won Shin, Ji Soo Yuk, Sang Hun Chun, Yong Taik Lim, Soong Ho Um · 2020

Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence Open

Chanyoung Song, Hathaichanok Phuengkham, Young Seob Kim, Van Vuong Dinh, In Ho Lee , et al. · 2019

Nanobarcoding: Topological Transformation‐Based Nanobarcoding for Detection and Enumeration of MicroRNAs and Single Nucleotide Polymorphism (Adv. Biosys. 7/2019) Open

Ji Soo Yuk, Seung Won Shin, Sang Hun Chun, Bo Mi Ku, Yu Jeong Choi , et al. · 2019

In article number 1900013, Soong Ho Um and co-workers report a new topological transformation-based nanobarcoding technique for the detection and enumeration of short RNAs like microRNAs and their single nucleotide polymorphisms. The RNA f…

Surface-Controlled Molecular Self-Alignment in Polymer Actuators for Flexible Microrobot Applications Open

M. S. Jang, Jun-Sik Kim, Ji-Hun Kim, Do Hyun Bae, Min Jun Kim , et al. · 2019

Polymer actuators are important components in lab-on-a-chip and micromechanical systems because of the inherent properties that result from their large and fast mechanical responses induced by molecular-level deformations (e.g., isomerizat…

Immunostimulatory activity of Y-shaped DNA nanostructures mediated through the activation of TLR9 Open

Gabsik Yang, Jung Eun Koo, Hye‐Eun Lee, Seung Won Shin, Soong Ho Um , et al. · 2019

Immunostimulatory oligodeoxynucleotides (DNAs) have been widely studied in pharmaceutical and biomedical research fields for applications in cancer immunotherapy and vaccination. Toll-like receptors (TLRs) are critical for the instruction …

Ultra-high curvature sensors for multi-bend structures using fiber Bragg gratings Open

M. S. Jang, Jun-Sik Kim, Soong Ho Um, Sungwook Yang, Jinseok Kim · 2019

Measuring high curvatures is essential in various applications such as structural engineering, medical treatment, and robotics. Herein, we present a novel ultra-high curvature sensor with an ultra-thin and highly flexible structure incorpo…

Revealing the Presence of a Symbolic Sequence Representing Multiple Nucleotides Based on K-Means Clustering of Oligonucleotides Open

Byoungsang Lee, So Yeon Ahn, Charles Park, James J. Moon, Jung Heon Lee , et al. · 2019

In biological systems, a few sequence differences diversify the hybridization profile of nucleotides and enable the quantitative control of cellular metabolism in a cooperative manner. In this respect, the information required for a better…

Regulation of cellular gene expression by nanomaterials Open

Sang Hun Chun, Ji Soo Yuk, Soong Ho Um · 2018

Fluorescence-coded DNA Nanostructure Probe System to Enable Discrimination of Tumor Heterogeneity via a Screening of Dual Intracellular microRNA Signatures in situ Open

Seung Won Shin, Byoung Sang Lee, Kisuk Yang, Lunjakorn Amornkitbamrung, M. S. Jang , et al. · 2017

Since the delivery kinetics of different cell types are different, the signal from the target cell is greatly affected by the noise signal of the diagnostic system. This is a major obstacle hindering the practical application of intracellu…

Design of gold nanoparticles-decorated SiO<sub>2</sub>@TiO<sub>2</sub> core/shell nanostructures for visible light-activated photocatalysis Open

Ryeri Lee, Yogeenth Kumaresan, Sei Young Yoon, Soong Ho Um, Il Keun Kwon , et al. · 2017

In this study, we designed core/shell nanostructures (CSNs) of silicon dioxide (SiO₂)/titanium dioxide (TiO₂), which were decorated with gold (Au) nanoparticles (NPs), to activate the visible light-driven photocatalyt…

Emerging string of fluid pearls Open

Seong Jin Kim, M. S. Jang, Soong Ho Um, Sunghwan Jung · 2016

This paper is associated with a poster winner of a 2015 APS/DFD Milton van Dyke Award for work presented at the DFD Gallery of Fluid Motion. The original poster is available from the Gallery of Fluid Motion, http://dx.doi.org/10.1103/APS.D…

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