John Vlot
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View article: Radial fan-based CO2 insufflation during laparoscopic surgery: a first-in-human study
Radial fan-based CO2 insufflation during laparoscopic surgery: a first-in-human study Open
Background Intra-abdominal pressure during laparoscopic insufflation with pressurized carbon dioxide (CO 2 ) gas is strongly influenced by mechanical ventilation. Resulting pressure fluctuations can destabilize the surgical workspace and p…
View article: Mortality and Surgery-Related Complications in Very Low and Extreme Low Birth Weight Infants Treated for Esophageal Atresia: A Multi-Center Cohort Study
Mortality and Surgery-Related Complications in Very Low and Extreme Low Birth Weight Infants Treated for Esophageal Atresia: A Multi-Center Cohort Study Open
Mortality and surgery-related complication rates in VLBW/ELBW infants after surgical EA repair in this large cohort are in line with previous studies. However, outcomes after surgical repair of EA are worse compared to infants born with a …
View article: Surgical workspace in porcine thoracoscopy with two-lung ventilation
Surgical workspace in porcine thoracoscopy with two-lung ventilation Open
In neonatal and pediatric thoracoscopy, two-lung ventilation is often used due to the size constraints of double-lumen tubes or selective bronchial blockers. Reducing the volume of both lungs to create surgical workspace requires moderatio…
View article: Collaborative Efforts in Pediatric Surgery: Lessons from European Randomized Controlled Trials
Collaborative Efforts in Pediatric Surgery: Lessons from European Randomized Controlled Trials Open
Conducting multicenter randomized controlled trials (RCTs) in pediatric surgery for rare congenital anomalies presents unique challenges, including low patient recruitment, complex regulatory landscapes, and variability in care standards. …
View article: Persisting Motor Function Problems in Children With Oesophageal Atresia Associated With Surgical Approach and Sports
Persisting Motor Function Problems in Children With Oesophageal Atresia Associated With Surgical Approach and Sports Open
Aim Children born with oesophageal atresia are at risk for impaired motor function, yet longitudinal data are lacking. This study aimed to assess overall motor functioning, motor domains and potential predictors at school age over time. Me…
View article: Does primary posterior tracheopexy prevent collapse of the trachea in newborns with oesophageal atresia and tracheomalacia? A study protocol for an international, multicentre randomised controlled trial (PORTRAIT trial)
Does primary posterior tracheopexy prevent collapse of the trachea in newborns with oesophageal atresia and tracheomalacia? A study protocol for an international, multicentre randomised controlled trial (PORTRAIT trial) Open
Introduction Tracheomalacia (TM) often occurs in children with oesophageal atresia (OA), leading to recurrent respiratory symptoms and in severe cases to blue spells or ultimately respiratory arrest. In some patients, a secondary posterior…
View article: Surgical conditions in experimental laparoscopy: effects of pressure, neuromuscular blockade, and pre-stretching on workspace volume
Surgical conditions in experimental laparoscopy: effects of pressure, neuromuscular blockade, and pre-stretching on workspace volume Open
Background Establishing a pneumoperitoneum for laparoscopy is common surgical practice, with the goal to create an optimal surgical workspace within the abdominal cavity while minimizing insufflation pressure. Individualized strategies, ba…
View article: The Value of Preoperative Rigid Tracheobronchoscopy for the Diagnosis of Tracheomalacia in Oesophageal Atresia Patients
The Value of Preoperative Rigid Tracheobronchoscopy for the Diagnosis of Tracheomalacia in Oesophageal Atresia Patients Open
Study of Diagnostics Test.
View article: Developing and validating an implantable suture tension sensor
Developing and validating an implantable suture tension sensor Open
The implantable suture tension sensor appeared to be capable of recording real time changes in suture tension, and the. validation process of this sensor has been initiated. With the information from devices like this, a much better unders…
View article: Automated control for investigation of the insufflation-ventilation interaction in experimental laparoscopy
Automated control for investigation of the insufflation-ventilation interaction in experimental laparoscopy Open
In laparoscopic surgery the abdominal cavity is insufflated with pressurized carbon dioxide gas to create workspace. This pressure is exerted through the diaphragm onto the lungs, competing with ventilation and hampering it. In clinical pr…
View article: A novel method for monitoring abdominal compliance to optimize insufflation pressure during laparoscopy
A novel method for monitoring abdominal compliance to optimize insufflation pressure during laparoscopy Open
Background Abdominal compliance describes the ease of expansion of the abdominal cavity. Several studies highlighted the importance of monitoring abdominal compliance (C ab ) during the creation of laparoscopic workspace to individualize t…
View article: Recommendations for endoscopic surveillance after esophageal atresia repair in adults
Recommendations for endoscopic surveillance after esophageal atresia repair in adults Open
Endoscopic surveillance of adults with esophageal atresia is advocated, but the optimal surveillance strategy remains uncertain. This study aimed to provide recommendations on appropriate starting age and intervals of endoscopic surveillan…
View article: The Safety of Intralesional Steroid Injections in Young Children and Their Effectiveness in Anastomotic Esophageal Strictures—A Meta-Analysis and Systematic Review
The Safety of Intralesional Steroid Injections in Young Children and Their Effectiveness in Anastomotic Esophageal Strictures—A Meta-Analysis and Systematic Review Open
Objective Intralesional steroid injections (ISI) are a widely used technique for various pediatric indications and represent a possible adjuvant treatment for anastomotic esophageal strictures. Yet, no consensus has been reached neither on…
View article: P048 A NEW MODALITY FOR BIOMECHANICAL VALIDATION OF CLOSURE TECHNIQUES OF LAPAROTOMIES
P048 A NEW MODALITY FOR BIOMECHANICAL VALIDATION OF CLOSURE TECHNIQUES OF LAPAROTOMIES Open
Aim Incisional hernia remains one of the most frequent complications after abdominal surgery. Several closure techniques exist. However, fundamental biomechanical understanding of these techniques and of the differences in clinical outcome…
View article: Primary repair of esophageal atresia is followed by multiple diagnostic and surgical procedures.
Primary repair of esophageal atresia is followed by multiple diagnostic and surgical procedures. Open
Patients with EA frequently require multiple anesthetics for a variety of procedures related to the EA, complications and comorbidities. This study can help care providers when counselling parents of a patient with an EA by giving them mor…
View article: Interventions with Music in PECTus excavatum treatment (IMPECT trial): a study protocol for a randomised controlled trial investigating the clinical effects of perioperative music interventions
Interventions with Music in PECTus excavatum treatment (IMPECT trial): a study protocol for a randomised controlled trial investigating the clinical effects of perioperative music interventions Open
Introduction Pectus excavatum repair is associated with substantial postoperative pain, despite the use of epidural analgesia and other analgesic regimens. Perioperative recorded music interventions have been shown to alleviate pain and an…
View article: Towards integrative neuromonitoring of the surgical newborn
Towards integrative neuromonitoring of the surgical newborn Open
BACKGROUND The altered neurodevelopment of children operated on during the neonatal period might be due to peri-operative changes in the homeostasis of brain perfusion. Monitoring of vital signs is a standard of care, but it does not usual…
View article: Intralesional steroid injections to prevent refractory strictures in patients with oesophageal atresia: study protocol for an international, multicentre randomised controlled trial (STEPS-EA trial)
Intralesional steroid injections to prevent refractory strictures in patients with oesophageal atresia: study protocol for an international, multicentre randomised controlled trial (STEPS-EA trial) Open
Introduction Anastomotic stricture formation is the most common postoperative complication after oesophageal atresia (OA) repair. The standard of care is endoscopic dilatation. A possible adjuvant treatment is intralesional steroid injecti…
View article: Risk factors for refractory anastomotic strictures after oesophageal atresia repair: a multicentre study
Risk factors for refractory anastomotic strictures after oesophageal atresia repair: a multicentre study Open
Objective To determine the incidence of refractory anastomotic strictures after oesophageal atresia (OA) repair and to identify risk factors associated with refractory strictures. Methods Retrospective national multicentre study in patient…
View article: Invited Brief Commentary on IUVS -2017-0216
Invited Brief Commentary on IUVS -2017-0216 Open
This article is referred to by:A Novel Laparoscopic Surgery Model with a Device to Expand the Abdominal Working Space in Rats: The Influence of Pneumoperitoneum and Skin Incision Length on Postoperative Inflammatory Cytokines