John Weinman
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View article: Minimal clinically important difference of the 6-Minute walk test and daily step count at 3 months following surgery for lumbar spinal stenosis
Minimal clinically important difference of the 6-Minute walk test and daily step count at 3 months following surgery for lumbar spinal stenosis Open
Purpose This study aimed to estimate the minimal clinically important difference (MCID) in two objective measures of walking: 6-minute walk distance (6MWD) and mean daily step count in patients with lumbar spinal stenosis, three months pos…
View article: PD08 Developing an effective intervention to improve photoprotection behaviour in xeroderma pigmentosum: results of the XPAND trial
PD08 Developing an effective intervention to improve photoprotection behaviour in xeroderma pigmentosum: results of the XPAND trial Open
Premature death in patients with xeroderma pigmentosum (XP) is most commonly due to metastatic skin cancer. In total, 80% of the skin cancers in XP are on the face, head and neck. So rigorous ultraviolet protection, especially of the face,…
View article: Best fit framework synthesis of qualitative studies on factors associated with medication nonadherence in people with type 2 diabetes using the COM‐B model
Best fit framework synthesis of qualitative studies on factors associated with medication nonadherence in people with type 2 diabetes using the COM‐B model Open
This review aimed to synthesize factors associated with medication nonadherence among people with type 2 diabetes (PwT2D), using the Capability, Opportunity, Motivation and Behaviour (COM‐B) model as the a priori model. Studies published b…
View article: The silent epidemic of non-adherence – insights from the 2024 a:care congress
The silent epidemic of non-adherence – insights from the 2024 a:care congress Open
Medication non-adherence is a global challenge with profound implications for patient health outcomes, healthcare systems, and society at large. This widespread issue leads to hundreds of thousands of preventable deaths and hospitalization…
View article: A validation study of the Intentional Nonadherence Scale among people with type 2 diabetes in the United Kingdom
A validation study of the Intentional Nonadherence Scale among people with type 2 diabetes in the United Kingdom Open
Aim To examine the psychometric properties of the Intentional Nonadherence Scale (INAS) among people with type 2 diabetes mellitus (PwT2D) in the United Kingdom. Methods This validation study recruited 260 PwT2D at diabetes intermediate ca…
View article: Best fit framework synthesis of qualitative studies on factors associated with medication nonadherence in people with type 2 diabetes using the COM‐B model
Best fit framework synthesis of qualitative studies on factors associated with medication nonadherence in people with type 2 diabetes using the COM‐B model Open
This review aimed to synthesize factors associated with medication nonadherence among people with type 2 diabetes (PwT2D), using the Capability, Opportunity, Motivation and Behaviour (COM‐B) model as the a priori model. Studies published b…
View article: Understanding beliefs about elexacaftor-tezacaftor-ivacaftor therapy in adults living with cystic fibrosis
Understanding beliefs about elexacaftor-tezacaftor-ivacaftor therapy in adults living with cystic fibrosis Open
Background A person’s beliefs about treatment influence their engagement and adherence to that treatment. The Necessity-Concerns Framework suggests that adherence is influenced by a person’s judgement of their own need for treatment (neces…
View article: Selection of Behavior Change Techniques for Asthma Medication Adherence Apps: Evidence-Based Design Study
Selection of Behavior Change Techniques for Asthma Medication Adherence Apps: Evidence-Based Design Study Open
Background Poor medication adherence is a widespread issue that causes adverse patient outcomes and is expensive for all aspects of the health care system. Developing cost-effective and scalable interventions to promote medication adherenc…
View article: Identifying modifiable factors that influence walking in patients undergoing surgery for neurogenic claudication: a prospective longitudinal study
Identifying modifiable factors that influence walking in patients undergoing surgery for neurogenic claudication: a prospective longitudinal study Open
Neurogenic claudication, caused by lumbar spinal stenosis, is the most common reason for spinal surgery in older adults, aiming to improve pain and walking. However, most people do not increase walking post-operatively. This study aimed to…
View article: A United Kingdom nationally representative survey of public attitudes towards pharmacogenomics
A United Kingdom nationally representative survey of public attitudes towards pharmacogenomics Open
Background Variation in DNA is known to contribute to medication response, impacting both medicine effectiveness and incidence of adverse drug reactions (ADRs). However, clinical implementation of pharmacogenomics (PGx) has been slow, and …
View article: Experiences of recovery and rehabilitation from surgery to treat neurogenic claudication. A qualitative study
Experiences of recovery and rehabilitation from surgery to treat neurogenic claudication. A qualitative study Open
This study aimed to explore the experiences, expectations, attitudes and beliefs about surgery and recovery in people with neurogenic claudication, and their preferences for rehabilitation. Semi-structured interviews were conducted with a …
View article: A cultural adaptation and validation study of the Intentional Nonadherence Scale (INAS) among people with type 2 diabetes in Singapore
A cultural adaptation and validation study of the Intentional Nonadherence Scale (INAS) among people with type 2 diabetes in Singapore Open
Our study supports the reliability and most aspects of validity of the INAS, which revealed new factors that may affect medication adherence and HbA1c. In clinical settings, healthcare providers may consider using this questionnaire to eva…
View article: Pharmacist interventions in the control of hypertension and adherence to anti-hypertensive treatment: A systematic review and meta-analysis of randomised controlled trials
Pharmacist interventions in the control of hypertension and adherence to anti-hypertensive treatment: A systematic review and meta-analysis of randomised controlled trials Open
Introduction Non-adherence to antihypertensive therapy is one of the major barriers for the achievement of blood pressure (BP) control and has a significant cost burden1. Non-adherence is also thought to be one of the leading factors leadi…
View article: A personalized and systematically designed adherence intervention improves photoprotection in adults with xeroderma pigmentosum (XP): results of the XPAND randomized controlled trial
A personalized and systematically designed adherence intervention improves photoprotection in adults with xeroderma pigmentosum (XP): results of the XPAND randomized controlled trial Open
Background Poor adherence to photoprotection in xeroderma pigmentosum (XP) increases morbidity and shortens lifespan due to skin cancers. Objectives To test a highly personalized intervention (XPAND) to reduce the dose of ultraviolet radia…
View article: Development and evaluation of a personalised psychological intervention to improve adherence to photoprotection in adults with Xeroderma Pigmentosum (XP)
Development and evaluation of a personalised psychological intervention to improve adherence to photoprotection in adults with Xeroderma Pigmentosum (XP) Open
Background Poor adherence to photoprotection from ultraviolet radiation in the rare disease xeroderma pigmentosum can be life-threatening due to heightened risk of skin cancers. This novel, two-phase research programme used mixed methods t…
View article: Acceptability of ‘as needed’ biologic therapy in psoriasis: insights from a multistakeholder mixed-methods study
Acceptability of ‘as needed’ biologic therapy in psoriasis: insights from a multistakeholder mixed-methods study Open
Background Biologic therapies have led to increasing numbers of patients with psoriasis who have clear or nearly clear skin. It is current practice to continue biologic therapy indefinitely in these patients, which contributes to a substan…
View article: Systematic Review Examining the Behavior Change Techniques in Medication Adherence Intervention Studies Among People With Type 2 Diabetes
Systematic Review Examining the Behavior Change Techniques in Medication Adherence Intervention Studies Among People With Type 2 Diabetes Open
Background Although previous systematic reviews have studied medication adherence interventions among people with Type 2 diabetes (PwT2D), no intervention has been found to improve medication adherence consistently. Furthermore, inconsiste…
View article: Participants’ experiences and acceptability of a home-based walking exercise behaviour-change intervention (MOtivating Structure walking Activity in people with Intermittent Claudication (MOSAIC))
Participants’ experiences and acceptability of a home-based walking exercise behaviour-change intervention (MOtivating Structure walking Activity in people with Intermittent Claudication (MOSAIC)) Open
Objectives
\nThis study explored the experiences and acceptability of a novel, home-based, walking exercise behaviour-change intervention (MOtivating Structured walking Activity in people with Intermittent Claudication (MOSAIC)) in adults …
View article: Can Smartphone Notifications Help With Gout Management? A Feasibility Study
Can Smartphone Notifications Help With Gout Management? A Feasibility Study Open
Objective This feasibility study aimed to assess the acceptability of using smartphone notifications to modify the medication beliefs of people with gout. We evaluated the feasibility and acceptability of a smartphone application using the…
View article: ‘Turning up and tuning in’. Factors associated with parental non‐attendance and non‐adherence in intervention for young children with speech, language communication needs
‘Turning up and tuning in’. Factors associated with parental non‐attendance and non‐adherence in intervention for young children with speech, language communication needs Open
Background When parents bring their child to appointments and then adhere to agreed speech and language therapy (SLT) recommendations, there is the potential to increase the intensity of the intervention, support generalization and improve…
View article: Adjunctive Medication Management and Contingency Management to enhance adherence to acamprosate for alcohol dependence: the ADAM trial RCT
Adjunctive Medication Management and Contingency Management to enhance adherence to acamprosate for alcohol dependence: the ADAM trial RCT Open
Background Acamprosate is an effective and cost-effective medication for alcohol relapse prevention but poor adherence can limit its full benefit. Effective interventions to support adherence to acamprosate are therefore needed. Objectives…
View article: Acceptability and influence of a complex personalized intervention on changes in photoprotection behaviours among people with xeroderma pigmentosum
Acceptability and influence of a complex personalized intervention on changes in photoprotection behaviours among people with xeroderma pigmentosum Open
Objectives Rigorous photoprotection is the only means to prevent skin cancer in people with the rare condition of xeroderma pigmentosum (XP). We conducted a qualitative process evaluation of patient experiences and responses to a highly pe…
View article: 1662 PILOT TESTING OF A BRIEF PRE-CONSULTATION MEDICINES ADHERENCE SCREENER IN A GERIATRIC OUTPATIENT SETTING
1662 PILOT TESTING OF A BRIEF PRE-CONSULTATION MEDICINES ADHERENCE SCREENER IN A GERIATRIC OUTPATIENT SETTING Open
Introduction In older adults, medicines non-adherence is prevalent and harmful. Current methods of identification have limitations with direct questioning often being met with a reluctance to “admit” non-adherence to healthcare professiona…
View article: Psoriasis and COVID-19: findings from PsoProtectMe.
Psoriasis and COVID-19: findings from PsoProtectMe. Open
The COVID-19 pandemic prompted the rapid mobilisation of the research community to investigate the impact on people with psoriasis.This led to the creation of the online patient-facing PsoProtectMe registry, developed in partnership with p…
View article: Selecting behaviour change techniques for asthma medication adherence apps: an evidence-based approach for developers (Preprint)
Selecting behaviour change techniques for asthma medication adherence apps: an evidence-based approach for developers (Preprint) Open
BACKGROUND Poor medication adherence is a widespread issue that causes adverse patient outcomes and is expensive to all aspects of the healthcare system. Developing cost-effective and scalable interventions to promote medication adherence…
View article: A Systematic Review of Patient-Reported Adherence Measures in Asthma: Which Questionnaire Is Most Useful in Clinical Practice?
A Systematic Review of Patient-Reported Adherence Measures in Asthma: Which Questionnaire Is Most Useful in Clinical Practice? Open
Based on this review, we recommend that when a PRAM is used, it should be the Test of the Adherence to Inhalers. However, the Adherence Starts with Knowledge-20 and Adherence Starts with Knowledge-12 may also be useful. Our results highlig…
View article: Observed and self-reported COVID-19 health protection behaviours on a university campus and the impact of a single simple intervention
Observed and self-reported COVID-19 health protection behaviours on a university campus and the impact of a single simple intervention Open
During the COVID-19 pandemic, most data on adherence to health protective behaviours were collected via a self-report. We quantified the discrepancy between self-report data and discretely observed behaviour in a sample of university staff…
View article: CareKnowDo—A Multichannel Digital and Telephone Support Program for People With Chronic Kidney Disease: Feasibility Randomized Controlled Trial
CareKnowDo—A Multichannel Digital and Telephone Support Program for People With Chronic Kidney Disease: Feasibility Randomized Controlled Trial Open
Background Chronic kidney disease (CKD) is a common, progressive condition. Lifestyle changes and antihypertensive medication can slow the progression to end-stage kidney disease, which requires renal replacement therapy. However, adherenc…
View article: Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey
Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey Open
Background Nonadherence to immune-modifying therapy is a complex behaviour which, before the COVID-19 pandemic, was shown to be associated with mental health disorders in people with immune-mediated diseases. The COVID-19 pandemic has led …