John Wikstrand
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View article: Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure
Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure Open
Patients with heart failure, left ventricular ejection fraction <50% and sinus rhythm should receive beta-blocker therapy even with moderate or moderately severe renal dysfunction.
View article: Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials
Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials Open
Aims Recent guidelines recommend that patients with heart failure and left ventricular ejection fraction (LVEF) 40–49% should be managed similar to LVEF ≥ 50%. We investigated the effect of beta-blockers according to LVEF in double-blind, …
View article: Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction
Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction Open
Aim We aimed to study the relationships of loop diuretic dose with renal function and clinical outcomes in patients with chronic heart failure ( HF ). Methods and results Loop diuretic dose at baseline was recorded in patients included in …
View article: Do statins reduce the risk of myocardial infarction in patients with heart failure? A pooled individual‐level reanalysis of CORONA and GISSI‐HF
Do statins reduce the risk of myocardial infarction in patients with heart failure? A pooled individual‐level reanalysis of CORONA and GISSI‐HF Open
Aims Current guidelines do not explicitly recommend statin use in heart failure ( HF ). Relatively low numbers of atherothrombotic events among HF patients, in the context of their elevated competing risks for non‐atherothrombotic causes o…