Joke Konings
YOU?
Author Swipe
View article: Impaired whole blood thrombin generation is associated with procedure-related bleeding in acutely decompensated cirrhosis
Impaired whole blood thrombin generation is associated with procedure-related bleeding in acutely decompensated cirrhosis Open
View article: Whole blood thrombin generation shows a significant hypocoagulable state in patients with decompensated cirrhosis
Whole blood thrombin generation shows a significant hypocoagulable state in patients with decompensated cirrhosis Open
View article: PB1143 Analytical Performance Evaluation of a New Stago System SthemO 201
PB1143 Analytical Performance Evaluation of a New Stago System SthemO 201 Open
View article: OC 45.4 Crucial Roles of Red Blood Cells and Platelets in Coagulation
OC 45.4 Crucial Roles of Red Blood Cells and Platelets in Coagulation Open
citH3; Cell Death Detection ELISAPlus Roche, modified), DNA-histone complexes (Cell Death Detection ELISAPlus) and calprotectin (Human Calprotectin ELISA Kit, Hycult Biotech).We performed the statistical analysis with SPSS v21.Results: PCd…
View article: PB1134 Determination and Verification of Reference Intervals on the Automated Coagulation Analyzer sthemO 301
PB1134 Determination and Verification of Reference Intervals on the Automated Coagulation Analyzer sthemO 301 Open
View article: Crucial roles of red blood cells and platelets in whole blood thrombin generation
Crucial roles of red blood cells and platelets in whole blood thrombin generation Open
Red blood cells (RBCs) and platelets contribute to the coagulation capacity in bleeding and thrombotic disorders. The thrombin generation (TG) process is considered to reflect the interactions between plasma coagulation and the various blo…
View article: Assessing the individual roles of FII, FV, and FX activity in the thrombin generation process
Assessing the individual roles of FII, FV, and FX activity in the thrombin generation process Open
Thrombin generation (TG) is known as a physiological approach to assess the hemostatic function. Although it correlates well with thrombosis and bleeding, in the current setup it is not sensitive to the effects of fluctuations in single co…
View article: Patients With Multiple Myeloma Have a Disbalanced Whole Blood Thrombin Generation Profile
Patients With Multiple Myeloma Have a Disbalanced Whole Blood Thrombin Generation Profile Open
Background Multiple myeloma (MM) is associated with a high prevalence of bleeding and an increased risk of thrombo-embolism. MM patients have reduced platelet- and red blood cell (RBC) numbers in blood, which may indicate that the paradoxi…
View article: A novel assay for studying the involvement of blood cells in whole blood thrombin generation
A novel assay for studying the involvement of blood cells in whole blood thrombin generation Open
View article: Implant stability in patients treated with platelet‐rich fibrin and bovine bone substitute for alveolar ridge preservation is associated with peripheral blood cells and coagulation factors
Implant stability in patients treated with platelet‐rich fibrin and bovine bone substitute for alveolar ridge preservation is associated with peripheral blood cells and coagulation factors Open
Aims The aim of the present study was to assess the association between dental implant stability and peripheral blood cell composition and levels of coagulation factors in patients treated with alveolar ridge preservation with platelet‐ric…
View article: The effects of oral contraceptive usage on thrombin generation and activated protein C resistance in Saudi women, with a possible impact of the body mass index
The effects of oral contraceptive usage on thrombin generation and activated protein C resistance in Saudi women, with a possible impact of the body mass index Open
As in other populations, our study demonstrated that OC usage induced prothrombotic changes in plasma of Saudi women, including resistance to the inhibitory actions of TM and APC. More specifically, OC usage in our population predominantly…
View article: Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test
Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test Open
The current study contributes to the translation of flow cytometry based platelet function testing from a scientific tool to a diagnostic test. Platelet function measurements, using prepared and stored platelet activation kits, are reprodu…
View article: Interindividual Variability and Normal Ranges of Whole Blood and Plasma Thrombin Generation
Interindividual Variability and Normal Ranges of Whole Blood and Plasma Thrombin Generation Open
Background Assays measuring thrombin generation (TG) in plasma increasingly gained attention in the field of thrombosis and hemostasis. Adaptation of the method enabled the measurement of TG in whole blood (WB). Despite their potential, TG…
View article: Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case–Control Study
Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case–Control Study Open
There are no significant differences between the thrombin generation profiles of PAD patients and healthy controls. Between PAD patients with and without cardiovascular event, the WB thrombin generation appears to differ. Mechanistically, …
View article: Hypoxia Induces a Prothrombotic State Independently of the Physical Activity
Hypoxia Induces a Prothrombotic State Independently of the Physical Activity Open
Hypoxia (oxygen deprivation) is known to be associated with deep vein thrombosis and venous thromboembolism. We attempted to get a better comprehension of its mechanism by going to high altitude, thereby including the potential contributin…