Þorvarður Jón Löve
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View article: Antimicrobial Use and Serious Infections Among Patients With Psoriatic Arthritis After Initiating Tumor Necrosis Factor Inhibitors: A Nationwide Matched Cohort Study
Antimicrobial Use and Serious Infections Among Patients With Psoriatic Arthritis After Initiating Tumor Necrosis Factor Inhibitors: A Nationwide Matched Cohort Study Open
In Table 1, the units for the last row were labelled incorrectly. The value in the parentheses represents the number of individuals affected by serious infections, as some individuals had > 1 event of a serious infection. The revised varia…
View article: The impact of TNF inhibitors on glucocorticoid use among patients with inflammatory arthritides: A nationwide cohort study
The impact of TNF inhibitors on glucocorticoid use among patients with inflammatory arthritides: A nationwide cohort study Open
Objectives: Tumour necrosis factor inhibitors (TNFi) effectively treat inflammatory arthritides and may reduce glucocorticoid dependence. This study investigates the impact of TNFi on glucocorticoid usage. Methods: This nationwide study in…
View article: Clinically Important Decrease in Liver Stiffness Following Treatment for Hepatitis C: Outcome of the TraP HepC Nationwide Elimination Program
Clinically Important Decrease in Liver Stiffness Following Treatment for Hepatitis C: Outcome of the TraP HepC Nationwide Elimination Program Open
Background/Objectives: Direct-acting antiviral (DAA) therapy has been highly successful in treating chronic hepatitis C (CHC). The nationwide Treatment as Prevention of Hepatitis C (TraP HepC) initiative that was launched in Iceland in 201…
View article: New Definition of Light Chain Monoclonal Gammopathy of Undetermined Significance
New Definition of Light Chain Monoclonal Gammopathy of Undetermined Significance Open
Importance Recent studies suggest standard reference intervals for serum free light chains (FLC) are inaccurate and that this problem can only be partially remedied by using separate reference intervals for individuals with impaired kidney…
View article: (025) A CAUTIONARY TALE: NONSTEROIDAL ANTI-INFLAMMATORY DRUG USE AND VULVODYNIA
(025) A CAUTIONARY TALE: NONSTEROIDAL ANTI-INFLAMMATORY DRUG USE AND VULVODYNIA Open
Introduction Localized provoked vulvodynia (LPV) is a chronic condition characterized by severe pain localized to the vulvar vestibule upon light touch. While the etiology of LPV remains incompletely understood, we now know that inflammati…
View article: Approaching hypercalcemia in monoclonal gammopathy of undetermined significance: insights from the iStopMM screening study
Approaching hypercalcemia in monoclonal gammopathy of undetermined significance: insights from the iStopMM screening study Open
Hypercalcemia in monoclonal gammopathy of undetermined significance (MGUS) presents a clinical challenge because it may indicate progression to multiple myeloma (MM) but could also be due to a multitude of unrelated disorders. To inform th…
View article: Analysis of smoldering multiple myeloma according to the target of the monoclonal immunoglobulin of patients
Analysis of smoldering multiple myeloma according to the target of the monoclonal immunoglobulin of patients Open
International audience
View article: The impact of first-line tumour necrosis factor inhibitor treatment on anti-infective use in patients with axial spondyloarthritis: a nationwide retrospective cohort study
The impact of first-line tumour necrosis factor inhibitor treatment on anti-infective use in patients with axial spondyloarthritis: a nationwide retrospective cohort study Open
Filled AIPs among axSpA patients increased after TNFi initiation in contrast to what has been documented in prior studies on severe infections. This indicates an increase in non-severe infections or a lower threshold for AIPs among physici…
View article: Depressive symptom trajectories among general population during the COVID-19 pandemic in Iceland: a prospective cohort study (2020–2023)
Depressive symptom trajectories among general population during the COVID-19 pandemic in Iceland: a prospective cohort study (2020–2023) Open
Introduction While changes in the prevalence of depressive symptoms during the COVID-19 pandemic have been described across populations, few studies have incorporated multidimensional variables to characterise the varying effects of the pa…
View article: Monoclonal gammopathy of undetermined significance with multiple paraproteins: A population‐based screening study
Monoclonal gammopathy of undetermined significance with multiple paraproteins: A population‐based screening study Open
Monoclonal gammopathy of undetermined significance (MGUS) is the precursor of multiple myeloma (MM) and related disorders. MGUS is characterized by asymptomatic paraproteinemia. In some cases, multiple paraproteins can be identified but th…
View article: Predictors of treatment outcomes for Hepatitis C infection in a nationwide elimination program in Iceland: The treatment as prevention for Hepatitis C (TraP HepC) study
Predictors of treatment outcomes for Hepatitis C infection in a nationwide elimination program in Iceland: The treatment as prevention for Hepatitis C (TraP HepC) study Open
By reengagement in care and prompt retreatment when needed, a cure rate of 95.5 % was achieved. Unstable housing, a potentially actionable factor is associated with poor outcome.
View article: Comparing DAPSA, DAPSA28, and DAS28‐CRP in Patients With Psoriatic Arthritis Initiating a First Tumor Necrosis Factor Inhibitor Across Nine European Countries
Comparing DAPSA, DAPSA28, and DAS28‐CRP in Patients With Psoriatic Arthritis Initiating a First Tumor Necrosis Factor Inhibitor Across Nine European Countries Open
Objective Because 66/68 joint counts are not always performed in routine care, we aimed to determine which of the modified 28‐joint disease activity index for psoriatic arthritis (DAPSA28) or 28‐joint disease activity score with C‐reactive…
View article: Development of a Multivariable Model to Predict the Need for Bone Marrow Sampling in Persons With Monoclonal Gammopathy of Undetermined Significance
Development of a Multivariable Model to Predict the Need for Bone Marrow Sampling in Persons With Monoclonal Gammopathy of Undetermined Significance Open
International Myeloma Foundation and the European Research Council.
View article: Patient-Reported Outcomes (PROs) and PRO Remission Rates in 12,262 Biologic-Naïve Patients With Psoriatic Arthritis Treated With Tumor Necrosis Factor Inhibitors in Routine Care
Patient-Reported Outcomes (PROs) and PRO Remission Rates in 12,262 Biologic-Naïve Patients With Psoriatic Arthritis Treated With Tumor Necrosis Factor Inhibitors in Routine Care Open
Objective To evaluate patient-reported outcomes (PROs) after initiation of tumor necrosis factor inhibitor (TNFi) treatment in European real-world patients with psoriatic arthritis (PsA). Further, to investigate PRO remission rates across …
View article: Prior cancer and risk of monoclonal gammopathy of undetermined significance: a population-based study in Iceland and Sweden
Prior cancer and risk of monoclonal gammopathy of undetermined significance: a population-based study in Iceland and Sweden Open
There is some evidence that a prior cancer is a risk factor for the development of multiple myeloma (MM). If this is true, prior cancer should be associated with higher prevalence or increased progression rate of monoclonal gammopathy of u…
View article: Trends of perceived disruption in healthcare services during the pandemic: findings from the COVID-19 National Resilience Cohort in Iceland
Trends of perceived disruption in healthcare services during the pandemic: findings from the COVID-19 National Resilience Cohort in Iceland Open
Background Coronavirus disease 2019 (COVID-19) caused major disruptions in healthcare services worldwide. Yet, little is known about the association between perceived disruption in healthcare services and socio-demographic factors, pre-exi…
View article: Immunophenotypic assessment of clonal plasma cells and B-cells in bone marrow and blood in the diagnostic classification of early stage monoclonal gammopathies: an iSTOPMM study
Immunophenotypic assessment of clonal plasma cells and B-cells in bone marrow and blood in the diagnostic classification of early stage monoclonal gammopathies: an iSTOPMM study Open
Monoclonal gammopathy of undetermined significance (MGUS) is the earliest discernible stage of multiple myeloma (MM) and Waldenström’s macroglobulinemia (WM). Early diagnosis of MG may be compromised by the low-level infiltration, undetect…
View article: Sex Differences in the Effectiveness of First‐Line Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis: Results From the European Spondyloarthritis Research Collaboration Network
Sex Differences in the Effectiveness of First‐Line Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis: Results From the European Spondyloarthritis Research Collaboration Network Open
Objective Women with psoriatic arthritis (PsA) may have reduced tumor necrosis factor inhibitor (TNFi) effectiveness compared to men. We examined sex differences in treatment response and retention rates during 24 months of follow‐up among…
View article: Risk Factors of Smoldering Multiple Myeloma: Results from the Screened Istopmm Study
Risk Factors of Smoldering Multiple Myeloma: Results from the Screened Istopmm Study Open
Introduction Smoldering multiple myeloma (SMM) is an asymptomatic precursor condition to multiple myeloma (MM) that carries a higher risk of progression to MM than monoclonal gammopathy of undetermined significance (MGUS). This study aimed…
View article: P894: INFECTION RISK BEFORE DIAGNOSIS OF MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE: RESULTS FROM THE SCREENED POPULATION-BASED ISTOPMM STUDY
P894: INFECTION RISK BEFORE DIAGNOSIS OF MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE: RESULTS FROM THE SCREENED POPULATION-BASED ISTOPMM STUDY Open
Topic: 13. Myeloma and other monoclonal gammopathies - Biology & Translational Research Background: Infections have often been hypothesized to play an etiological role in multiple myeloma (MM) and monoclonal gammopathy of undetermined sign…