Jonas N. Pedersen
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Young probing fluorescence microscopy: Single-pixel imaging free of array-type actuators Open
Past realizations of single-pixel imaging have relied on array-type actuators to encode structural information in well-defined patterns in space, thus enabling image synthesis while circumventing the need for cameras. In microscopy, the bi…
Impact of Synergy Partner Cel7B on Cel7A Binding Rates: Insights from Single-Molecule Data Open
Enzymatic degradation of cellulosic biomass is a well-established route for the sustainable production of biofuels, chemicals, and materials. A strategy employed by nature and industry to achieve an efficient degradation of cellulose is th…
Quantifying DNA-mediated liposome fusion kinetics with a fluidic trap Open
DNA-induced liposome fusion kinetics measured in a nanofluidic trap follows second-order kinetics.
Trapping, characterization and reactions of biocolloids in a salinity gradient Open
The properties of soft matter nanoparticles like exosomes are interesting for drug delivery and diagnostics applications. However, the simultaneous characterization of multiple properties, e.g., size and zeta potential, can only be done se…
Confined Brownian Motion Tracked With Motion Blur: Estimating Diffusion Coefficient and Size of Confining Space Open
Mesoscopic environments and particles diffusing in them are often studied by tracking such particles individually while their Brownian motion explores their environment. Environments may be, e.g., a domain in a cell membrane, an interior c…
View article: ENDURUNS: An Integrated and Flexible Approach for Seabed Survey Through Autonomous Mobile Vehicles
ENDURUNS: An Integrated and Flexible Approach for Seabed Survey Through Autonomous Mobile Vehicles Open
The oceans cover more than two-thirds of the planet, representing the vastest part of natural resources. Nevertheless, only a fraction of the ocean depths has been explored. Within this context, this article presents the H2020 ENDURUNS pro…
Single-molecule DNA-mapping and whole-genome sequencing of individual cells Open
Significance We report optical mapping of DNA from a single cell. Notably, we demonstrate isolation of single cells, DNA extraction, and optical mapping, all within a single integrated micro-/nanofluidic device. Single-cell optical mapping…
Concentrating and labeling genomic DNA in a nanofluidic array Open
Genomic DNA is concentrated in a dense nanofluidic array and labeled by a polymerase ϕ29 reaction where neither the DNA nor the enzyme is attached to a solid support.
Site Application of a Channel Network Model for Groundwater Flow and Transport in Crystalline Rock Open
Groundwater flow and transport in deep crystalline rock is an important area of research. This is partly due to its relevance for constructing a long term repository for storing radioactive spent nuclear fuel in deep bedrock. Understanding…
Enrichment of megabase-sized DNA molecules for single-molecule optical mapping and next-generation sequencing Open
Next-generation sequencing (NGS) has caused a revolution, yet left a gap: long-range genetic information from native, non-amplified DNA fragments is unavailable. It might be obtained by optical mapping of megabase-sized DNA molecules. Freq…
How to connect time-lapse recorded trajectories of motile microorganisms with dynamical models in continuous time Open
We provide a tool for data-driven modeling of motility, data being time-lapse recorded trajectories. Several mathematical properties of a model to be found can be gleaned from appropriate model-independent experimental statistics, if one u…
Comment on “Temporal Correlations of the Running Maximum of a Brownian Trajectory” Open
Received 25 August 2016DOI:https://doi.org/10.1103/PhysRevLett.117.248901© 2016 American Physical SocietyPhysics Subject Headings (PhySH)Research AreasBrownian motionDiffusionStochastic processesTechniquesExtreme event statisticsFirst pass…
Classification of DNA nucleotides with transverse tunneling currents Open
It has been theoretically suggested and experimentally demonstrated that fast and low-cost sequencing of DNA, RNA, and peptide molecules might be achieved by passing such molecules between electrodes embedded in a nanochannel. The experime…
How to determine local stretching and tension in a flow-stretched DNA molecule Open
We determine the nonuniform stretching of and tension in a mega base pairs-long fragment of deoxyribonucleic acid (DNA) that is flow stretched in a nanofluidic chip. We use no markers, do not know the contour length of the DNA, and do not …
How to determine local stretching and tension in a flow-stretched DNA molecule Open
We determine the nonuniform stretching of and tension in a mega base pairs-long fragment of deoxyribonucleic acid (DNA) that is flow stretched in a nanofluidic chip. We use no markers, do not know the contour length of the DNA, and do not …