Jonas Bendig
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View article: Cognitive structure and progression in Parkinson’s Disease: Insights from a tablet-based assessment
Cognitive structure and progression in Parkinson’s Disease: Insights from a tablet-based assessment Open
Cognitive impairment represents an important burden for patients with Parkinson’s disease (PwPD). Digital tools may improve accessibility and provide richer assessments than traditional paper–pencil tests; open-source generation can suppor…
View article: Serum glial fibrillary protein reflects early brain injury dynamics and cognitive changes after deep brain stimulation surgery
Serum glial fibrillary protein reflects early brain injury dynamics and cognitive changes after deep brain stimulation surgery Open
View article: Portable transcranial therapeutic ultrasound enhances targeted gene delivery for Parkinson’s disease: from rodent models to non-human primates
Portable transcranial therapeutic ultrasound enhances targeted gene delivery for Parkinson’s disease: from rodent models to non-human primates Open
Gene therapy for neurodegenerative diseases faces significant challenges due to the blood-brain barrier (BBB), which limits drug delivery to the central nervous system (CNS). While clinical trials for Parkinson’s disease (PD) have progress…
View article: Electroconvulsive therapy promotes striatal dopaminergic recovery in a mouse model of Parkinson’s disease
Electroconvulsive therapy promotes striatal dopaminergic recovery in a mouse model of Parkinson’s disease Open
View article: High-Resolution Focused Ultrasound Neuromodulation of the Mouse Cortex Induces Lateralized Motor Responses in Awake Mice
High-Resolution Focused Ultrasound Neuromodulation of the Mouse Cortex Induces Lateralized Motor Responses in Awake Mice Open
View article: High-resolution focused ultrasound neuromodulation in awake mice induces robust lateralized motor responses
High-resolution focused ultrasound neuromodulation in awake mice induces robust lateralized motor responses Open
View article: Serum Glial Fibrillary Acidic Protein (GFAP) as a Potential Biomarker for Monitoring Postoperative Complications in Deep Brain Stimulation Surgery
Serum Glial Fibrillary Acidic Protein (GFAP) as a Potential Biomarker for Monitoring Postoperative Complications in Deep Brain Stimulation Surgery Open
Deep brain stimulation (DBS) is an efficient treatment for movement disorders, most commonly Parkinson’s Disease (PD), dystonia and essential tremor. DBS surgery carries risks, e.g. the risk of delayed peri-lead edema (PLE) and the risk of…
View article: Displacement and functional ultrasound (fUS) imaging of displacement-guided focused ultrasound (FUS) neuromodulation in mice
Displacement and functional ultrasound (fUS) imaging of displacement-guided focused ultrasound (FUS) neuromodulation in mice Open
Focused ultrasound (FUS) stimulation is a promising neuromodulation technique with the merits of non-invasiveness, high spatial resolution, and deep penetration depth. However, simultaneous imaging of FUS-induced brain tissue displacement …
View article: Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology
Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology Open
View article: Functional ultrasound (fUS) imaging of displacement-guided focused ultrasound (FUS) neuromodulation in mice
Functional ultrasound (fUS) imaging of displacement-guided focused ultrasound (FUS) neuromodulation in mice Open
Focused ultrasound (FUS) stimulation is a promising neuromodulation technique with the merits of non-invasiveness, high spatial resolution, and deep penetration depth. However, simultaneous imaging of FUS-induced brain tissue displacement …
View article: Aging and Parkinson’s disease: a complex interplay of vulnerable neurons, the immune system and the blood-brain barrier
Aging and Parkinson’s disease: a complex interplay of vulnerable neurons, the immune system and the blood-brain barrier Open
Aging is the biggest risk factor for Parkinson’s disease (PD) and a particular vulnerability of dopaminergic neurons in the substantia nigra to aging-associated effects has been firmly established. More recent work has revealed an importan…
View article: Transcranial Functional Ultrasound Imaging Detects Focused Ultrasound Neuromodulation Induced Hemodynamic Changes In Vivo
Transcranial Functional Ultrasound Imaging Detects Focused Ultrasound Neuromodulation Induced Hemodynamic Changes In Vivo Open
Background: Focused ultrasound (FUS) is an emerging non-invasive technique for neuromodulation in the central nervous system (CNS). Functional ultrasound imaging (fUSI) leverages ultrafast Power Doppler Imaging (PDI) to detect changes in c…
View article: Serum neurofilament indicates accelerated neurodegeneration and predicts mortality in late-stage Parkinson’s disease
Serum neurofilament indicates accelerated neurodegeneration and predicts mortality in late-stage Parkinson’s disease Open
Different stages of Parkinson’s disease (PD) are defined by clinical criteria, while late-stage PD is marked by the onset of morbidity milestones and rapid clinical deterioration. Based on neuropathological evidence, degeneration in the do…
View article: A Semantic Relatedness Model for the Automatic Cluster Analysis of Phonematic and Semantic Verbal Fluency Tasks Performed by People With Parkinson Disease: Prospective Multicenter Study
A Semantic Relatedness Model for the Automatic Cluster Analysis of Phonematic and Semantic Verbal Fluency Tasks Performed by People With Parkinson Disease: Prospective Multicenter Study Open
Background Phonematic and semantic verbal fluency tasks (VFTs) are widely used to capture cognitive deficits in people with neurodegenerative diseases. Counting the total number of words produced within a given time frame constitutes the m…
View article: Serum Neurofilament Predicts Mortality and Indicates Accelerated Neurodegeneration in Late-Stage Parkinson’s Disease
Serum Neurofilament Predicts Mortality and Indicates Accelerated Neurodegeneration in Late-Stage Parkinson’s Disease Open
Background A high percentage of dopaminergic axons are already lost at the time of diagnosis, current studies on neuroprotective agents focus mainly on the early stages of Parkinson’s disease (PD). Nevertheless, PD progresses slowly during…
View article: A Semantic Relatedness Model for the Automatic Cluster Analysis of Phonematic and Semantic Verbal Fluency Tasks Performed by People With Parkinson Disease: Prospective Multicenter Study (Preprint)
A Semantic Relatedness Model for the Automatic Cluster Analysis of Phonematic and Semantic Verbal Fluency Tasks Performed by People With Parkinson Disease: Prospective Multicenter Study (Preprint) Open
BACKGROUND Phonematic and semantic verbal fluency tasks (VFTs) are widely used to capture cognitive deficits in people with neurodegenerative diseases. Counting the total number of words produced within a given time frame constitutes the …
View article: The use of wearables for the diagnosis and treatment of Parkinson’s disease
The use of wearables for the diagnosis and treatment of Parkinson’s disease Open
View article: Measuring the Usability of eHealth Solutions for Patients With Parkinson Disease: Observational Study
Measuring the Usability of eHealth Solutions for Patients With Parkinson Disease: Observational Study Open
Background Parkinson disease (PD) is a neurodegenerative disorder with a variety of motor and nonmotor symptoms. Many of these symptoms can be monitored by eHealth solutions, including smartphone apps, wearable sensors, and camera systems.…
View article: Development and Validation of a Fall Questionnaire for Patients with Parkinson's Disease
Development and Validation of a Fall Questionnaire for Patients with Parkinson's Disease Open
Background In Parkinson's disease, postural instability and falls are of particular socioeconomic relevance. Although effective fall prevention and the prophylaxis of fall‐related injuries depend on low‐threshold symptom monitoring, valida…
View article: Feasibility of a Multimodal Telemedical Intervention for Patients with Parkinson’s Disease—A Pilot Study
Feasibility of a Multimodal Telemedical Intervention for Patients with Parkinson’s Disease—A Pilot Study Open
Symptoms of Parkinson’s disease (PD) can be controlled well, but treatment often requires expert judgment. Telemedicine and sensor-based assessments can allow physicians to better observe the evolvement of symptoms over time, in particular…
View article: Serum neurofilament indicates that DBS surgery can cause neuronal damage whereas stimulation itself does not
Serum neurofilament indicates that DBS surgery can cause neuronal damage whereas stimulation itself does not Open
View article: Author Correction: Label-Free Imaging of Tissue Architecture during Axolotl Peripheral Nerve Regeneration in Comparison to Functional Recovery
Author Correction: Label-Free Imaging of Tissue Architecture during Axolotl Peripheral Nerve Regeneration in Comparison to Functional Recovery Open
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View article: Label-free Imaging of Tissue Architecture during Axolotl Peripheral Nerve Regeneration in Comparison to Functional Recovery
Label-free Imaging of Tissue Architecture during Axolotl Peripheral Nerve Regeneration in Comparison to Functional Recovery Open