Jonas Mars
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View article: <scp>RNA</scp> tomography reveals spatial gene expression maps of <i>Arabidopsis thaliana</i> roots infected with <i>Heterodera schachtii</i>
<span>RNA</span> tomography reveals spatial gene expression maps of <i>Arabidopsis thaliana</i> roots infected with <i>Heterodera schachtii</i> Open
Summary Plant‐parasitic cyst nematodes, such as Heterodera schachtii , cause substantial crop losses world‐wide and induce specialized feeding structures in host roots, yet the molecular mechanisms underlying feeding structure initiation a…
View article: A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory
A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory Open
Epigenetic information can be inherited through a process known as transgenerational epigenetic inheritance (TEI). TEI can be initiated and maintained by small RNAs and histone modifications. The latter includes histone methylation, deposi…
View article: Low-cost, rapid and reliable DNA extraction from mammalian organoids using a C. elegans toolbox
Low-cost, rapid and reliable DNA extraction from mammalian organoids using a C. elegans toolbox Open
High-quality DNA extraction from organoids is an important step in molecular genetics research. Here, we show that a lysis buffer from the field of Caenorhabditis elegans research, called Single Worm Lysis Buffer (SWLB), is a low-co…
View article: Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration
Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration Open
Zebrafish hearts can regenerate by replacing damaged tissue with new cardiomyocytes. Although the steps leading up to the proliferation of surviving cardiomyocytes have been extensively studied, little is known about the mechanisms that co…
View article: Spatial transcriptomics of the nematode Caenorhabditis elegans using RNA tomography
Spatial transcriptomics of the nematode Caenorhabditis elegans using RNA tomography Open
RNA tomography or tomo-seq combines mRNA sequencing and cryo-sectioning to spatially resolve gene expression. We have adapted this method for the nematode Caenorhabditis elegans to generate anteroposterior gene expression maps at ne…
View article: A switch from noncanonical to canonical Wnt signaling stops neuroblast migration through a Slt–Robo and RGA-9b/ARHGAP–dependent mechanism
A switch from noncanonical to canonical Wnt signaling stops neuroblast migration through a Slt–Robo and RGA-9b/ARHGAP–dependent mechanism Open
Significance Cell migration is a central process in development, homeostasis, and disease. Among the extracellular signaling molecules that control this process are members of the Wnt family of secreted glycoproteins, which trigger distinc…