Hans‐Jonas Meyer
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The role of adipose tissue in liver fat accumulation: a sex-specific analysis in an exploratory cross-sectional study Open
Introduction Visceral (VAT), subcutaneous (SFT), and total body fat (FM) contribute to hepatic steatosis, yet their relative and sex-specific effects across total, regional, and site-specific levels remain unclear. We investigated associat…
Outcomes of pediatric kidney re-transplantation: a single-center cohort study Open
Children with end-stage renal disease (ESRD) frequently require more than one kidney transplantation (KT) during their lifetime due to limited graft longevity. Despite this clinical reality, few studies have evaluated long-term outcomes fo…
Lower limb malalignment on whole-leg radiography predicts medial or lateral talar osteochondral lesion location: Implications for osteoarthritis assessment Open
Lower limb malalignment and talar tilt are independent predictors of OCD localization. Coronal plane deviations and joint morphology alter load across the talar dome, contributing to medial or lateral predilection. Whole-leg alignment anal…
View article: Pleural tail sign in computed tomography-guided lung biopsy: an imaging predictor of severe pneumothorax requiring chest tube placement
Pleural tail sign in computed tomography-guided lung biopsy: an imaging predictor of severe pneumothorax requiring chest tube placement Open
The identification of a triangular PTS on pre-interventional CT imaging may help to stratify patients at higher risk of severe pneumothorax following CT-guided lung biopsy. This could enable more informed procedural planning, potentially l…
Comparison of fluoroscopy time and procedure time of endovascular interventions with and without prior angiography simulator training: a meta-analysis Open
Background Angiography simulator training (AST) can help to train important clinical aspects of complex angiography procedures before real patient contact. The aim of the present analysis was to synthesize the results of studies on endovas…
Prognostic relevance of contrast extravasation in patients undergoing endovascular embolization of acute bleeding Open
Objectives Contrast extravasation on imaging studies is a clinical surrogate for bleeding severity. However, the prognostic relevance of this imaging sign needs to be evaluated. The aim of this study was to analyze the impact of contrast e…
Prognostic relevance of CT-defined body composition in esophageal cancer patients undergoing curative treatment Open
In total, 51 patients (35.2 %) of the patient cohort died within the observation period. According to the sarcopenia threshold of the SMI, 99 patients (68.2 %) were classified as sarcopenic and according to the VAT threshold, 102 patients …
Body composition predicts poor outcomes and reveals immunometabolic dysfunction via single-cell profiling in anti-BCMA CAR T-treated myeloma Open
Chimeric Antigen Receptor (CAR) T-cell therapy has transformed the treatment of relapsed or refractory multiple myeloma (RRMM), yet outcomes remain heterogenous. The prognostic role of body composition in this context is unknown. We retros…
Efficacy and safety of percutaneous thermal ablation in Bosniak III and IV cystic renal masses: a systematic review and meta-analysis Open
Local thermal ablation is an effective and safe procedure for treating cystic kidney masses.
View article: Technical Recommendation on Multi-Driver Multifrequency MR Elastography for Tomographic Mapping of Abdominal Stiffness With a Focus on the Pancreas and Pancreatic Ductal Adenocarcinoma
Technical Recommendation on Multi-Driver Multifrequency MR Elastography for Tomographic Mapping of Abdominal Stiffness With a Focus on the Pancreas and Pancreatic Ductal Adenocarcinoma Open
Objectives: MR elastography (MRE) offers valuable mechanical tissue characterization for clinical diagnosis. However, conventional single-driver, single-frequency MRE systems are often limited by insufficient coverage of deep-seated organs…
Associations between MRI radiomics analysis and tumor-micro milieu in uterine cervical cancer Open
Purpose The complex interactions of the tumor micromilieu could be reflected by magnetic resonance imaging (MRI) when analyzed with the radiomics approach. For several tumor entities, it has been shown that radiomics derived from MRI can r…
View article: Prognostic Implications of Splenomegaly in BCMA-Directed CAR T-Cell Therapy for Relapsed Myeloma
Prognostic Implications of Splenomegaly in BCMA-Directed CAR T-Cell Therapy for Relapsed Myeloma Open
Spleen size may serve as a promising prognostic marker in CAR T-cell therapy for RRMM patients, providing a simple and readily accessible tool for enhancing risk stratification. This finding could inform monitoring strategies and optimize …
Associations between the SMARS score derived from CT and MRI with histopathological features in HCC Open
There are complex associations between the imaging phenotype and underlying histopathology of hepatocellular carcinomas (HCC). The recently proposed SMARS score (acronym comprising S hape of tumour, M osaic architecture, A FP level, R im A…
Prognostic significance of PET/CT for CAR T cell therapy in relapsed/refractory multiple myeloma Open
PET/CT plays an important role in staging of multiple myeloma (MM) and detecting extramedullary disease (EMD); however, its role in patients treated with commercially available CAR T cell therapies is unclear. We evaluated 61 patients trea…
View article: Prognostic value of CT-defined coronary sclerosis in COVID-19: results of a multicenter study based on the Weston score
Prognostic value of CT-defined coronary sclerosis in COVID-19: results of a multicenter study based on the Weston score Open
Coronary calcification, as defined by computed tomography (CT), can be quantified with a score (CAC score). It is an established prognostic and predictive imaging marker of the cardiovascular risk profile. The prognostic relevance of the C…
CT texture analysis of lymph nodes for improved staging accuracy in patients with colon cancer. Open
Introduction: Texture analysis can provide quantitative imaging markers and better characterize tumor tissue in oncological imaging. The present analysis investigated the diagnostic benefit of computed tomography (CT) derived texture analy…
Radiomics for Growth Prediction of Vestibular Schwannomas in Neurofibromatosis Type 2 Open
Bimodally distributed radiomics features from initial MRIs did not reliably predict rapid tumor growth (error probability: 23%) but may aid in planning MRI follow-up intervals.
Coronary artery calcification score as a prognostic factor in younger patients with multiple myeloma undergoing autologous stem cell therapy Open
Background Coronary artery calcification (CAC) scoring can be performed as a by-product of computed tomography (CT). CAC scoring may reflect the general cardiovascular risk profile of patients. The aim of the present study was to determine…
View article: Association of Lifestyle‐Induced Weight Loss With Gene Expression in Subcutaneous Adipose Tissue in Metabolic Syndrome
Association of Lifestyle‐Induced Weight Loss With Gene Expression in Subcutaneous Adipose Tissue in Metabolic Syndrome Open
Aims Lifestyle‐induced weight loss (LIWL) is considered an effective therapy for the treatment of metabolic syndrome (MetS). The role of differentially expressed genes (DEGs) in adipose tissue function and in the success of LIWL in MetS is…
The sagitta in 3D reconstruction of linea alba on routine CT scans is predictive of postoperative burst abdomen Open
Purpose Burst abdomen (BA) is a relevant complication after abdominal surgery that causes additional surgical procedures, prolonged hospital stays and long-term morbidity. Several underlying risk factors exist and have been characterized p…
View article: Association between diffusion-weighted imaging and tumor matrix in liver cancer: a cross-sectional study
Association between diffusion-weighted imaging and tumor matrix in liver cancer: a cross-sectional study Open
ADC values are not associated with collagen IV expression in liver tumors. The complex extracellular matrix is not reflected by the DWI signal, which can be discussed as mainly be influenced by the cellularity of the tumors. Further resear…
Effects of Protamine Reversal on Coagulation Parameters After High-Dose Heparin Administration in Percutaneous Hepatic Chemosaturation Intervention Open
Background: Intravenous protamine administration for heparin reversal after percutaneous hepatic chemosaturation intervention is generally recommended, but its effectiveness on coagulation parameters remains unclear. Methods: In a single-c…
View article: Association between radiomics of diffusion-weighted imaging and histopathology in hepatocellular carcinoma. A preliminary investigation
Association between radiomics of diffusion-weighted imaging and histopathology in hepatocellular carcinoma. A preliminary investigation Open
Radiomics features of the ADC maps can reflect the underlying histopathology in HCC patients including the proliferation potential and tumor-stroma ratio but not CD45 positive cells and tumor grading. The complex interactions between quant…
View article: Comparison of CT-Guided Microwave Ablation of Liver Malignancies with and Without Intra-Arterial Catheter Placement for Contrast Administration
Comparison of CT-Guided Microwave Ablation of Liver Malignancies with and Without Intra-Arterial Catheter Placement for Contrast Administration Open
Background: The aim of this study was to compare microwave ablation (MWA) with and without prior placement of an intra-arterial catheter for the purpose of application of contrast medium (CM). Methods: 148 patients (45 female, 65.1 ± 14.9 …
View article: Associations between dynamic-contrast enhanced MRI with histopathological features in atypical HCC using spatial co-registration with biopsy
Associations between dynamic-contrast enhanced MRI with histopathological features in atypical HCC using spatial co-registration with biopsy Open
DCE-MRI is associated with Ki 67 index in atypical HCC. The hepatobiliary phase could discriminate HCCs according to their Ki 67 index. Quantitative MRI could be used as an imaging-based surrogate for proliferative HCC. Further studies are…
CT Texture Analysis in Breast Cancer Patients Undergoing CT-Guided Bone Biopsy: Correlations With Histopathology Open
Background: Texture analysis has the potential to deliver quantitative imaging markers. Patients receiving computed tomography (CT)-guided percutaneous bone biopsies could be characterized using texture analysis derived from CT. Especially…