Jonas Nygren
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Patients’ Experiences of Diagnostic and Therapeutic High-Resolution Endoscopy in Treating Anal Squamous Intraepithelial Lesions: A Qualitative Study Open
Background: Anal squamous cell carcinoma is a rare disease strongly associated with the human papillomavirus (HPV) and preceded by the premalignant anal squamous intraepithelial lesion (ASIL). High-resolution anoscopy (HRA) using a colposc…
Laparoscopic Ladd's procedure for intestinal malrotation in adults: a single center experience Open
Introduction Laparoscopic Ladd’s procedure (LLP) is an established technique to treat intestinal malrotation, a congenital condition that may lead to volvulus and bowel obstruction. Traditionally, Ladd’s procedure has been performed using …
Impact of perineal healing on oncological outcome following surgery for squamous cell carcinoma of the anus Open
Aim Perineal wound complications are common following salvage surgery in anal cancer. It is not fully known if healing disorders have an impact on oncological outcomes. The aim of this study is to investigate survival in relation to perine…
Colorectal Cancer Surgery at a Regional Cold Site Centre During the SARS‐CoV‐2 Pandemic: A Comparison With Prepandemic Practices Open
Introduction Stockholm, Sweden had among the highest excess mortality rates during the first wave of the SARS‐CoV‐2 pandemic. In March 2020, an entire hospital implemented an infection‐free cold site infrastructure and scaled up imperative…
71935 - Endoscopic screening for anal high grade squamous intraepithelial dysplasia in HIV-positive men who have sex with men Open
Introduction Anal Squamous Intraepithelial Lesions (ASIL) are precursors to anal cancer. The highest risk is found in HIV-positive men having sex with men (MSM). The aim of the study is to evaluate flexible endoscopy as a screening method …
Stoma‐related complications and quality‐of‐life assessment: A cross‐sectional study with patients from Ethiopia and Sweden Open
Background The situation for patients with ostomy can be challenging, probably more in a resource‐constrained environment. Our objective was to evaluate quality of life (QoL) (using EQ5D‐5L) and stoma‐specific QoL (using Stoma QoL) in a hi…
Predictors of preparedness for recovery following colorectal cancer surgery: a latent class trajectory analysis Open
Contrary to the received view that emphasizes standardized care practices, our results point to the need for adding person-centred and tailored approaches that consider individual differences in how patients are prepared before and during …
Endoscopic underwater detection and resection of anal squamous intraepithelial lesions in non-anesthetized patients – a feasibility study and comparison with standard surgical treatment Open
Underwater resection using a HR flexible endoscope in non-anesthetized is a new, feasible and well tolerated method for ASILs treatment. Its efficacy and risk of complications seem comparable to standard surgical treatment while avoiding g…
Splenic flexure mobilization and anastomotic leakage in anterior resection for rectal cancer: A multicentre cohort study Open
Background and objective: Some colorectal surgeons advocate routine splenic flexure mobilization (SFM) when performing anterior resection for rectal cancer to ensure a tension-free anastomosis. Meta-analyses of smaller studies suggest that…
Multimodal Analgesia Bundle and Postoperative Opioid Use Among Patients Undergoing Colorectal Surgery Open
Importance A key objective in contemporary surgery is to reduce or eliminate the usage of opioids to minimize gastrointestinal adverse effects, fatigue, and long-term opioid dependency. Objectives To evaluate the association of the impleme…
Trends in Treatment of Colorectal Cancer and Short-term Outcomes During the First Wave of the COVID-19 Pandemic in Sweden Open
In this Swedish register-based cohort study of patients who received a diagnosis of colorectal cancer during the most intense period of the COVID-19 pandemic, a significant increase in ostomy formation for patients with colon cancer and a …
Colon cancer treatment in Sweden during the <span>COVID</span>‐19 pandemic: A nationwide register‐based study Open
Aim The COVID‐19 pandemic has reduced the capacity to diagnose and treat cancer worldwide due to the prioritization of COVID‐19 treatment. The aim of this study was to investigate treatment and outcomes of colon cancer in Sweden before and…
Perineal healing following salvage surgery for anal cancer Open
Aim Approximately 25% of anal cancer patients undergo abdominoperineal excision or more extensive surgery. Following surgery, a high perineal complication rate has been reported. Enhanced recovery after surgery (ERAS) is an evidence‐based …
Hernia at the stoma site after loop ileostomy reversal Open
Purpose To estimate the incidence of and risk factors for stoma site hernia after closure of a temporary diverting ileostomy. Method In a non-comparative cohort study, charts ( n = 216) and CT-scans ( n = 169) from patients who had undergo…
Patienters läkemedelsanvändning vid inskrivning inför elektiv urologisk kirurgi Open
Elective urological patients’ medication usage at the time of admission Author: Nygren. J. Supervisor: Gillespie. U. Examiner: Nielsen. E. Department of Pharmaceutical Biosciences, division of pharmacokinetics and drug therapy. Faculty of …
View article: Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS<sup>®</sup>) Society Recommendations: 2018
Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS<sup>®</sup>) Society Recommendations: 2018 Open
Background This is the fourth updated Enhanced Recovery After Surgery (ERAS ® ) Society guideline presenting a consensus for optimal perioperative care in colorectal surgery and providing graded recommendations for each ERAS item within th…
Best practice in major elective rectal/pelvic surgery: enhanced recovery after surgery (ERAS) Open
Within traditional clinical care, the postoperative recovery after pelvic/rectal surgery has been slow with high morbidity and long hospital stay. The enhanced recovery after surgery program is a multimodal approach to perioperative care d…