Explanipedia

Design and rationale of the MIGHTEE study: Motivational interviewing and group heart transplant exercise and education Open

Jonathan B. Edelson, Lauren M. Schneider, Shannon O’Malley, Jessica Somogie, Jing Huang , et al. · 2025

Background: Many pediatric heart transplant (HT) recipients have decreased physical activity, which worsens their cardiovascular risk profile, contributes to long-term morbidity and mortality, and is associated with lower quality of life (…

Allosensitization status predicts excess mortality in pediatric congenital heart disease transplant recipients in the current era: An analysis of the United Network for Organ Sharing database Open

Matthew J. O’Connor, Courtney Vu, Xuemei Zhang, Laura Bennett, Humera Ahmed , et al. · 2025

Highly sensitized patients with congenital heart disease undergoing heart transplantation in the current era experience 25% 1-year mortality. The magnitude of sensitization predicts adverse outcomes.

Listing for Pediatric Donation After Circulatory Death Heart Transplantation Is Associated With Improved Waitlist Outcomes Open

Michael A. Catalano, Max Shin, Omar Toubat, Radhika Rastogi, Halil Beqaj , et al. · 2025

Background Advances in procurement techniques have enabled use of hearts obtained via donation after circulatory death (DCD), expanding the donor pool; however, the impact of DCD heart transplant on outcomes in children is not well describ…

Contemporary outcomes and health care costs associated with single-ventricle heart failure admissions in adults in the United States Open

Michael A. Catalano, Jonathan B. Edelson, Omar Toubat, Halil Beqaj, Benjamin Smood , et al. · 2025

SV-ACHD represents a small proportion of adult HF admissions, although they have increased rates of procedure utilization and increased total costs. Risk of in-hospital mortality has improved over time in SV-ACHD patients, but there remain…

Feasibility of an Individualized Exercise Training Program for Children with Hypertrophic Cardiomyopathy Open

Joschka Wanner, Danielle S. Burstein, Stephen M. Paridon, Maully Shah, Shannon O’Malley , et al. · 2025

Limited data exist to guide exercise participation in pediatric hypertrophic cardiomyopathy (HCM) patients. Exercise is traditionally restricted in this population, despite research in adults with HCM demonstrating exercise-associated card…

Identifying the determinants of health–related quality of life in children after heart transplant Open

Jonathan B. Edelson, Jing Huang, Zi Wang, Vicky Tam, Debra Lefktowitz , et al. · 2025

Capturing Physiological Data in Children With Heart Failure Using Wearable Digital Technology: Lessons From Pilot Project Open

David M. Peng, Jonathan B. Edelson, Harishwara R. Gureddygari, T. Duganiero, Áine Lynch , et al. · 2025

Hardly a Windfall Open

Avital Ludomirsky, Jonathan B. Edelson, Kimberly Y. Lin, Justin H. Berger, Matthew J. O’Connor , et al. · 2025

Shining a Light on Cardiopulmonary Fitness in Pediatric Inherited Cardiac Disease Open

William Russell, Jonathan B. Edelson · 2025

Safety and Efficacy of GLP-1 Agonists in a Cohort of Patients with Fontan Circulation Open

Andrew M. Freddo, Humera Ahmed, Jonathan B. Edelson, Juan Ortega–Legaspi, Sumeet S. Vaikunth · 2024

The impact of neighborhood factors on exercise capacity in children with hypertrophic cardiomyopathy Open

Imran Masood, Lei Wang, Helen M. Stanley, Jonathan J. Edwards, Humera Ahmed , et al. · 2024

Background Restricting certain patients with hypertrophic cardiomyopathy (HCM) from exercise likely has negative cardiovascular effects and may not reduce the risk of sudden cardiac death. Promoting exercise in children with HCM is complex…

Subspecialty Health Care Utilization in Pediatric Patients With Muscular Dystrophy in the United States Open

Susan Matesanz, Jonathan B. Edelson, Katherine A. Iacobellis, Erika Mejia, John F. Brandsema , et al. · 2024

The rate of annual neurology follow-up and corticosteroid use in patients with DBMD is low. Medicaid insurance status was independently associated with a decreased likelihood of neurology follow-up, while age was not, suggesting that facto…

Identifying the Environmental Determinants of Health-Related Quality of Life in Children After Heart Transplant Open

Jonathan B. Edelson, Jing Huang, Z. Wang, D. Lefkowitz, Matthew J. O’Connor , et al. · 2024

Panel Reactive Antibody, Crossmatch Status, and Outcomes in Pediatric Heart Transplant Recipients with Congenital Heart Disease: An Analysis of the United Network for Organ Sharing Database Open

Matthew J. O’Connor, X. Zhang, L. Michelle Bennett, C. Vu, Humera Ahmed , et al. · 2024

Cardiopulmonary exercise testing on adaptive equipment in children and adults with <span>Friedreich</span> ataxia Open

Nicolette Cilenti, Jaclyn Tamaroff, Christopher J. Capiola, Walter Faig, Michael G. McBride , et al. · 2024

Introduction/Aims Traditional exercise is often difficult for individuals with Friedreich ataxia (FRDA), and evidence is limited regarding how to measure exercise performance in this population. We evaluated the feasibility, reliability, a…

Emergency Department Use and Hospital Mortality Among Heart Transplant Recipients in the United States Open

Luise Holzhauser, Nosheen Reza, Jonathan J. Edwards, Edo Y. Birati, Anjali Owens , et al. · 2024

Background Annual heart transplant (HT) volumes have increased, as have post‐HT outpatient care needs. Data on HT‐related emergency department (ED) visits are limited. Methods and Results A retrospective analysis of 177 450 HT patient ED v…

Characteristics and outcomes of children determined to be noncandidates for heart transplant Open

Sarah Bell, Justin H. Berger, Carley Boyle, Jonathan B. Edelson, Jonathan J. Edwards , et al. · 2024

Age-specific determinants of reduced exercise capacity in youth after heart transplant: A longitudinal cohort study Open

Nathan Markiewitz, Meghan B. Lane‐Fall, Jingtao Huang, Laura Mercer‐Rosa, K. M. Stack , et al. · 2024

Pediatric patients on veno-arterial extracorporeal membrane oxygenation undergoing cardiac rehabilitation have better outcomes Open

Jonathan B. Edelson, Luke Wooster, Jing Huang, Zhongmin Wang, James T. Connelly , et al. · 2024

Mobilization in a pediatric VA-ECMO cohort was achieved by 1/10 patients, is associated with heart transplant and survival to hospital discharge, and is not associated with ECMO-related adverse events. Mobility in certain pediatric VA-ECMO…

Introduction of transcatheter edge‐to‐edge repair in patients with congenital heart disease at a children's hospital Open

Matthew A. Jolley, Analise Sulentic, Silvani Amin, Mudit Gupta, Stephen Ching , et al. · 2023

Background Atrioventricular valve regurgitation (AVVR) is a devastating complication in children and young adults with congenital heart disease (CHD), particularly in patients with single ventricle physiology. Transcatheter edge‐to‐edge re…

Mechanical circulatory support in pediatric myocarditis: Support strategies and outcomes in a nationally representative cohort Open

Alicia M. Kamsheh, Jonathan B. Edelson, Jennifer Faerber, Antara Mondal, William Quarshie , et al. · 2023

A novel intracorporeal right ventricular assist device implantation technique in a young patient Open

Constantine Mavroudis, Madison A. Grasty, Kathryn Restaino, Catherine M. Montgomery, A Pettit , et al. · 2023

Hybrid stage 1 palliation with simultaneous off-pump ventricular assist device placement in neonates with high-risk single ventricle anatomy: Initial experience Open

Constantine Mavroudis, Matthew J. O’Connor, Carol Wittlieb‐Weber, Jonathan B. Edelson, Jonathan J. Edwards , et al. · 2023

The Effect of Udenafil on Heart Rate and Blood Pressure in Adolescents With the Fontan Circulation Open

Jonathan B. Edelson, Victor Zak, David Goldberg, Greg Fleming, Andrew S. Mackie , et al. · 2023

Hypertension: An Important But Reversible Cause of Systolic Dysfunction in a Cohort of Pediatric Patients Open

Alicia M. Kamsheh, Kevin Meyers, Robert A. Palermo, Lezhou Wu, Danielle S. Burstein , et al. · 2023

Exercise and Sports Participation in Children with Cardiomyopathy: A Review Open

Imran Masood, Jonathan B. Edelson · 2023

Purpose of review There are numerous health benefits to exercise, including improved cardiovascular, metabolic, and mental health. Despite these many benefits, children with cardiomyopathy have been traditionally restricted from engaging i…

Reduced incidence of cardiac rejection in multi‐organ transplants: A propensity matched study Open

Jonathan B. Edelson, Xuemei Zhang, Andrew B. Goldstone, Joseph W. Rossano, Matthew J. O’Connor , et al. · 2023

Recipients of HKi and HLi experience a reduced risk of rejection when compared to H, but an equivalent risk of 1 yr mortality. These findings have important implications for the future of HT medicine.

Temporal trends in primary payers in pediatric heart transplant and association with long‐term survival Open

Kathryn Restaino, Xuemei Zhang, Jennifer Faerber, Joseph W. Rossano, Danielle S. Burstein , et al. · 2023

Background Pediatric heart transplantation (HT) is resource intensive. In adults, there has been an increase in the proportion of HTs funded by public insurance, with post‐HT outcomes inferior to those funded by private sources. Trends in …

Cardiopulmonary Exercise Testing in Pediatric Patients With Hypertrophic Cardiomyopathy Open

Jonathan B. Edelson, Helen M. Stanley, Jungwon Min, Danielle S. Burstein, Meghan B. Lane‐Fall , et al. · 2022

EST is clinically useful in select pediatric patients with HCM. Ectopy on EST is a risk factor for cardiac death, cardiac transplant, and arrhythmias requiring implantable cardioverter-defibrillator.

Association of Donors With US Public Health Service Risk Criteria and Outcomes After Adult vs Pediatric Cardiac Transplant Open

Danielle S. Burstein, Joseph W. Rossano, JoAnn Lindenfeld, Kelly Schlendorf, Nhue Do , et al. · 2022

Importance The United Network for Organ Sharing (UNOS) evaluates donor risk for acute transmission of HIV, hepatitis B, or hepatitis C based on US Public Health Services (PHS)–specific criteria. However, recent data regarding use and outco…

Jonathan B. Edelson YOU? Author Swipe