Jonathan Boomer
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View article: Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease
Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease Open
Background Idiopathic interstitial pneumonias (IIPs), such as idiopathic pulmonary fibrosis and interstitial pneumonia with autoimmune features, present diagnostic and therapeutic challenges due to their heterogeneous nature. This study ai…
View article: Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease
Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease Open
Background Idiopathic interstitial pneumonias (IIPs) such as idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia with autoimmune features (IPAF), present diagnostic and therapeutic challenges due to their heterogeneous nature. T…
View article: Azithromycin to Prevent Recurrent Wheeze Following Severe Respiratory Syncytial Virus Bronchiolitis
Azithromycin to Prevent Recurrent Wheeze Following Severe Respiratory Syncytial Virus Bronchiolitis Open
Azithromycin therapy for 14 days during acute severe RSV bronchiolitis did not reduce recurrent wheeze occurrence over the following 2 to 4 years. Our data suggest no benefit of azithromycin administration with the goal of preventing recur…
View article: The azithromycin to prevent wheezing following severe RSV bronchiolitis-II clinical trial: Rationale, study design, methods, and characteristics of study population
The azithromycin to prevent wheezing following severe RSV bronchiolitis-II clinical trial: Rationale, study design, methods, and characteristics of study population Open
View article: Identifying Responders to Bronchial Thermoplasty in Severe Asthma
Identifying Responders to Bronchial Thermoplasty in Severe Asthma Open
View article: Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: Results from SARP-3
Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: Results from SARP-3 Open
View article: QCT-based Measures Of Airway Narrowing And Shape Changes Associated With Endobronchial Biopsy Tissue Measures of Airway Remodeling And Clinical Outcomes In Asthma
QCT-based Measures Of Airway Narrowing And Shape Changes Associated With Endobronchial Biopsy Tissue Measures of Airway Remodeling And Clinical Outcomes In Asthma Open
View article: Type 2 inflammation in the sputum of adolescents with asthma
Type 2 inflammation in the sputum of adolescents with asthma Open
View article: Airway Remodeling in Severe Asthma Is Associated with Increased Muc5AC and Decreased Cilia-Related Gene Expression
Airway Remodeling in Severe Asthma Is Associated with Increased Muc5AC and Decreased Cilia-Related Gene Expression Open
View article: Impaired tumor necrosis factor‐α secretion by CD4 T cells during respiratory syncytial virus bronchiolitis associated with recurrent wheeze
Impaired tumor necrosis factor‐α secretion by CD4 T cells during respiratory syncytial virus bronchiolitis associated with recurrent wheeze Open
Background Infants with severe respiratory syncytial virus (RSV) bronchiolitis have an increased risk of recurrent wheezing and asthma. We aimed to evaluate the relationships between regulatory T cell (Treg) percentage and cytokine product…
View article: Clinical significance of the bronchodilator response in children with severe asthma
Clinical significance of the bronchodilator response in children with severe asthma Open
Background Our objective was to determine those characteristics associated with reversibility of airflow obstruction and response to maximal bronchodilation in children with severe asthma through the Severe Asthma Research Program (SARP). …
View article: The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium
The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium Open
Bacterial permeability family member A1 (BPIFA1), also known as short palate, lung, and nasal epithelium clone 1 (SPLUNC1), is a protein involved in the antiinflammatory response. The goal of this study was to determine whether BPIFA1 expr…
View article: Vitamin D3 treatment of vitamin D–insufficient asthmatic patients does not alter immune cell function
Vitamin D3 treatment of vitamin D–insufficient asthmatic patients does not alter immune cell function Open
View article: Temporal biological variability in dendritic cells and regulatory T cells in peripheral blood of healthy adults
Temporal biological variability in dendritic cells and regulatory T cells in peripheral blood of healthy adults Open
View article: Increased Nasal Plasmacytoid Dendritic Cells Are Associated with Recurrent Wheezing Following Severe RSV Bronchiolitis
Increased Nasal Plasmacytoid Dendritic Cells Are Associated with Recurrent Wheezing Following Severe RSV Bronchiolitis Open