Jonathan Devos
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View article: Interaction of amyloid beta with humanin and acetylcholinesterase is modulated by ATP
Interaction of amyloid beta with humanin and acetylcholinesterase is modulated by ATP Open
Humanin (HN) is known to bind amyloid beta (Aβ)‐inducing cytoprotective effects, while binding of acetylcholinesterase (AChE) to Aβ increases its aggregation and cytotoxicity. Previously, we showed that binding of HN to Aβ blocks aggregati…
View article: Biochemical determinants of the IGFBP‐3–hyaluronan interaction
Biochemical determinants of the IGFBP‐3–hyaluronan interaction Open
IGFBP‐3, the most abundant IGFBP and the main carrier of insulin‐like growth factor I (IGF‐I) in the circulation, can bind IGF‐1 with high affinity, which attenuates IGF/IGF‐IR interactions, thereby resulting in antiproliferative effects. …