Jonathan Freimark
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View article: 42The impact of belzutifan on tumor reduction procedures and healthcare resource utilization in von hippel–lindau (VHL) disease
42The impact of belzutifan on tumor reduction procedures and healthcare resource utilization in von hippel–lindau (VHL) disease Open
Background Belzutifan, a hypoxia-inducible factor 2 alpha inhibitor, was approved in the United States in August 2021 to treat VHL-associated renal cell carcinoma (RCC), central nervous system hemangioblastomas (CNS-Hb), and pancreatic neu…
View article: Epidemiology and economic burden of Von Hippel-Lindau Disease-associated central nervous system hemangioblastomas and pancreatic neuroendocrine tumors in the United States
Epidemiology and economic burden of Von Hippel-Lindau Disease-associated central nervous system hemangioblastomas and pancreatic neuroendocrine tumors in the United States Open
Background To date, real-world evidence around the clinical and economic burden related to von Hippel-Lindau (VHL) disease is limited. Therefore, this study characterized the prevalence, healthcare resource utilization (HRU), and economic …
View article: Functional and Clinical Outcomes Associated with Steroid Treatment among Non-ambulatory Patients with Duchenne Muscular Dystrophy
Functional and Clinical Outcomes Associated with Steroid Treatment among Non-ambulatory Patients with Duchenne Muscular Dystrophy Open
Background: Evidence on the long-term efficacy of steroids in Duchenne muscular dystrophy (DMD) after loss of ambulation is limited. Objective: Characterize and compare disease progression by steroid treatment (prednisone, deflazacort, or …
View article: Post‐transplant maintenance therapy in patients with <i>FLT3</i>‐mutated acute myeloid leukemia: Real‐world treatment patterns and outcomes
Post‐transplant maintenance therapy in patients with <i>FLT3</i>‐mutated acute myeloid leukemia: Real‐world treatment patterns and outcomes Open
Objectives Maintenance therapy is one strategy to prolong survival in patients with acute myeloid leukemia (AML) following hematopoietic stem cell transplantation (HSCT). We evaluated real‐world treatment patterns and outcomes in patients …
View article: Impact of PASI response on work productivity and the effect of risankizumab on indirect costs using machine learning in patients with moderate-to-severe psoriasis
Impact of PASI response on work productivity and the effect of risankizumab on indirect costs using machine learning in patients with moderate-to-severe psoriasis Open
To compare the impact of Psoriasis Area and Severity Index (PASI) response on total work productivity impairment (TWPI) in patients with moderate-to-severe psoriasis; to compare TWPI and associated indirect costs among patients treated wit…
View article: A Longitudinal Assessment of the Impact of Endometriosis on Patients’ Salary Growth and Risk of Leaving the Workforce
A Longitudinal Assessment of the Impact of Endometriosis on Patients’ Salary Growth and Risk of Leaving the Workforce Open
Patients with endometriosis experienced lower annual salary and salary growth, as well as higher risks of work loss events, compared with matched controls.
View article: Real-world outcomes of long-term prednisone and deflazacort use in patients with Duchenne muscular dystrophy: experience at a single, large care center
Real-world outcomes of long-term prednisone and deflazacort use in patients with Duchenne muscular dystrophy: experience at a single, large care center Open
Aim: To assess outcomes among patients with Duchenne muscular dystrophy receiving deflazacort or prednisone in real-world practice. Methods: Clinical data for 435 boys with Duchenne muscular dystrophy from Cincinnati Children’s Hospital Me…