Jonathan C. Hsu
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View article: Leveraging a randomized trial to assess relationships between transeptal puncture, brain emboli, and migraine symptoms
Leveraging a randomized trial to assess relationships between transeptal puncture, brain emboli, and migraine symptoms Open
Transseptal puncture was not associated with visual auras; however, acute brain emboli involving the visual cortex were associated with such symptoms. These data suggest that transseptal puncture is not causal in migraine-related visual au…
View article: Evaluating the role of clinical decision support systems in medication safety for older people: a systematic review
Evaluating the role of clinical decision support systems in medication safety for older people: a systematic review Open
Background Older people are particularly vulnerable to medication errors and adverse drug events (ADEs) due to polypharmacy and age-related physiological changes. Clinical decision support systems (CDSS) presents itself as a potential solu…
View article: Same‐Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States
Same‐Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States Open
Background Patients undergoing atrial fibrillation (AF) ablation have historically been hospitalized overnight or longer postprocedure. National rates of same‐day discharge (SDD) following AF ablation remain unknown. Methods and Results Th…
View article: Arrhythmia Recurrence and Rhythm Control Strategies After Catheter Ablation of Newly Diagnosed Atrial Fibrillation (ARRC-AF Study)
Arrhythmia Recurrence and Rhythm Control Strategies After Catheter Ablation of Newly Diagnosed Atrial Fibrillation (ARRC-AF Study) Open
In this study, additional rhythm-control strategies were frequently continued after index ablation. One in 6 patients underwent repeat ablation, with the majority receiving concomitant AAD therapy. These data indicate that a combined strat…
View article: Racial and Ethnic Disparities in the Use and Outcomes With WATCHMAN FLX: A SURPASS Analysis of the NCDR Left Atrial Appendage Occlusion Registry
Racial and Ethnic Disparities in the Use and Outcomes With WATCHMAN FLX: A SURPASS Analysis of the NCDR Left Atrial Appendage Occlusion Registry Open
Background Left atrial appendage occlusion (LAAO) is increasingly used as an alternative to oral anticoagulation for stroke prevention in select patients with atrial fibrillation. Data on outcomes in racial and ethnic minority individuals …
View article: Association of chronic kidney disease and kidney failure with replacement therapy with procedural and long-term outcomes after first-generation Watchman device: Insights from the NCDR LAAO Registry
Association of chronic kidney disease and kidney failure with replacement therapy with procedural and long-term outcomes after first-generation Watchman device: Insights from the NCDR LAAO Registry Open
CKD and KFRT were associated with higher rates of procedural complications and 1-year adverse events and death, but no difference in the 1-year rate of stroke.
View article: CONNECT: Coordinating Options for Neurovascular Patients Needing Electrophysiology Consults and Treatments
CONNECT: Coordinating Options for Neurovascular Patients Needing Electrophysiology Consults and Treatments Open
Background and Purpose Though Event Monitors (EM) and Implantable Loop Recorders (ILR) are prevalent in stroke workups, complex processes to obtain placement of these device might result in delays. Our aim was to determine if the CONNECT (…
View article: Catheter ablation vs advanced therapy for patients with severe heart failure and ventricular electrical storm
Catheter ablation vs advanced therapy for patients with severe heart failure and ventricular electrical storm Open
Patients with severe HF and ES who underwent VT ablation had similar overall survival to patients who directly proceeded with advanced therapy, although rates of HT were high during follow-up. Predictors of HT or mortality after catheter a…
View article: Racial and Ethnic Disparities in the Utilization and Outcomes with WATCHMAN FLX: A SURPASS analysis of the NCDR LAAO Registry
Racial and Ethnic Disparities in the Utilization and Outcomes with WATCHMAN FLX: A SURPASS analysis of the NCDR LAAO Registry Open
Background Left atrial appendage occlusion (LAAO) is increasingly used as an alternative to oral anticoagulation for stroke prevention in select patients with atrial fibrillation. Data on outcomes in racial and ethnic minority individuals …
View article: Impact of artificial intelligence arrhythmia mapping on time to first ablation, procedure duration, and fluoroscopy use
Impact of artificial intelligence arrhythmia mapping on time to first ablation, procedure duration, and fluoroscopy use Open
Introduction Artificial intelligence (AI) ECG arrhythmia mapping provides arrhythmia source localization using 12‐lead ECG data; whether this information impacts procedural efficiency is unknown. We performed a retrospective, case‐control …
View article: Pulsed Field Ablation Index–Guided Ablation for Lesion Formation: Impact of Contact Force and Number of Applications in the Ventricular Model
Pulsed Field Ablation Index–Guided Ablation for Lesion Formation: Impact of Contact Force and Number of Applications in the Ventricular Model Open
BACKGROUND: The effect of contact force (CF) on lesion formation is not clear during pulsed field ablation (PFA). The aim of this study was to evaluate the impact of CF, PFA, and their interplay through the PFA index (PF index) formula on …
View article: Radiotherapy for hyoid bone metastasis from lung adenocarcinoma: A case report
Radiotherapy for hyoid bone metastasis from lung adenocarcinoma: A case report Open
BACKGROUND Metastasis to the hyoid bone is an exceptionally rare occurrence, with documented cases limited to breast, liver, colon, skin, lung, and prostate cancers. This report highlights an unusual case involving the metastasis of lung a…
View article: Stroke Prevention in Atrial Fibrillation: Our Current Failures and Required Research
Stroke Prevention in Atrial Fibrillation: Our Current Failures and Required Research Open
Nonvalvular atrial fibrillation is a common rhythm disorder of middle-aged to older adults that can cause ischemic strokes and systemic embolism. Lifelong use of oral anticoagulants reduces the risk of these ischemic events but increases t…
View article: Characterizing cardiac contractile motion for noninvasive radioablation of ventricular tachycardia
Characterizing cardiac contractile motion for noninvasive radioablation of ventricular tachycardia Open
The degree of cardiac contractile motion varies significantly (1 mm to 15.2 mm) across different locations in the heart. The effect of contractile motion on the precision of radiotherapy should be assessed on a patient-specific basis.
View article: Response to Letter to the Editor
Response to Letter to the Editor Open
To the editor, We thank Kataoka et al. for their comments regarding our recently published article on catheter ablation of atrial fibrillation in very elderly patients (≥80 years old).1 While the unadjusted time-to-event analysis may be mo…
View article: Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R
Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R Open
Tumor-associated inflammation drives cancer progression and therapy resistance, with the infiltration of monocyte-derived tumor-associated macrophages (TAMs) associated with poor prognosis in diverse cancers. Targeting TAMs holds potential…