Jonathan List
YOU?
Author Swipe
View article: Watching Single Unmodified Enzymes at Work
Watching Single Unmodified Enzymes at Work Open
Many proteins undergo conformational changes during their activity. A full understanding of the function of these proteins can only be obtained if different conformations and transitions between them can be monitored in aqueous solution, w…
View article: Tuning the Diameter, Stability, and Membrane Affinity of Peptide Pores by DNA-Programmed Self-Assembly
Tuning the Diameter, Stability, and Membrane Affinity of Peptide Pores by DNA-Programmed Self-Assembly Open
Protein pores recently enabled a breakthrough in bioanalytics by making it possible to sequence individual DNA and RNA strands during their translocation through the lumen of the pore. Despite this success and the overall promise of nanopo…
View article: Emergence of colloidal patterns in AC electrical fields
Emergence of colloidal patterns in AC electrical fields Open
Suspended microparticles subjected to AC electrical fields collectively organize into band patterns perpendicular to the field direction. The bands further develop into zigzag shaped patterns, in which the particles are observed to circula…
View article: Complete aggregation pathway of amyloid β (1-40) and (1-42) resolved on an atomically clean interface
Complete aggregation pathway of amyloid β (1-40) and (1-42) resolved on an atomically clean interface Open
High-resolution atomic force microscopy provides clean imaging of amyloid aggregates at graphene-water interface.
View article: Detection of HER2+ Breast Cancer Cells using Bioinspired DNA-Based Signal Amplification
Detection of HER2+ Breast Cancer Cells using Bioinspired DNA-Based Signal Amplification Open
Circulating tumor cells (CTC) are promising biomarkers for metastatic cancer detection and monitoring progression. However, CTC detection remains challenging due to their low frequency and heterogeneity. Herein, we report a bioinspired app…
View article: Detection of HER2+ Breast Cancer Cells using Bioinspired DNA-Based Signal Amplification
Detection of HER2+ Breast Cancer Cells using Bioinspired DNA-Based Signal Amplification Open
Circulating tumor cells (CTC) are promising biomarkers for metastatic cancer detection and monitoring progression. However, CTC detection remains challenging due to their low frequency and heterogeneity. Herein, we report a bioinspired app…
View article: Detection of HER2<sup>+</sup> Breast Cancer Cells using Bioinspired DNA‐Based Signal Amplification
Detection of HER2<sup>+</sup> Breast Cancer Cells using Bioinspired DNA‐Based Signal Amplification Open
Circulating tumor cells (CTC) are promising biomarkers for metastatic cancer detection and monitoring progression. However, detection of CTCs remains challenging due to their low frequency and heterogeneity. Herein, we report a bioinspired…
View article: Templated Assembly of Pore-forming Peptides in Lipid Membranes
Templated Assembly of Pore-forming Peptides in Lipid Membranes Open
Pore-forming peptides are of interest due to their antimicrobial activity and ability to form gateways through lipid membranes. Chemical modification of these peptides makes it possible to arrange several peptide monomers into well-defined…
View article: A Bio-Inspired Amplification Cascade for the Detection of Rare Cancer Cells
A Bio-Inspired Amplification Cascade for the Detection of Rare Cancer Cells Open
The main cause of cancer-related death is due to cancer cell spreading and formation of secondary tumors in distant organs, the so-called metastases. Metastatic cancer cells are detectable in the blood of cancer patients as circulating tum…
View article: Nanopore‐Based, Rapid Characterization of Individual Amyloid Particles in Solution: Concepts, Challenges, and Prospects
Nanopore‐Based, Rapid Characterization of Individual Amyloid Particles in Solution: Concepts, Challenges, and Prospects Open
Aggregates of misfolded proteins are associated with several devastating neurodegenerative diseases. These so‐called amyloids are therefore explored as biomarkers for the diagnosis of dementia and other disorders, as well as for monitoring…
View article: Reconfigurable DNA Nanostructures
Reconfigurable DNA Nanostructures Open
In this thesis several reconfigurable nano devices, capable of conformational changes will be presented. The DNA origami technique was employed to fabricate the components. Two extensively studied systems, a switchable hydrophobic envelope…
View article: Membrane-Assisted Growth of DNA Origami Nanostructure Arrays
Membrane-Assisted Growth of DNA Origami Nanostructure Arrays Open
Biological membranes fulfill many important tasks within living organisms. In addition to separating cellular volumes, membranes confine the space available to membrane-associated proteins to two dimensions (2D), which greatly increases th…