Jonathan M. Bock
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View article: Dysphagia Outcomes in Zenker Diverticulum: A Longitudinal <scp>POuCH</scp> Study
Dysphagia Outcomes in Zenker Diverticulum: A Longitudinal <span>POuCH</span> Study Open
Objective Patients with cricopharyngeus muscle dysfunction (CPMD) with and without diverticula (e.g., Zenker Diverticulum) often struggle with dysphagia for years prior to diagnosis or intervention. Surgical treatment is successful; yet, t…
View article: Evaluating the effectiveness of psilocybin in alleviating distress among cancer patients: A systematic review
Evaluating the effectiveness of psilocybin in alleviating distress among cancer patients: A systematic review Open
Objectives Psychological and existential distress is prevalent among patients with life-threatening cancer, significantly impacting their quality of life. Psilocybin-assisted therapy has shown promise in alleviating these symptoms. This sy…
View article: A Consensus Statement on the Administration of Systemic Bevacizumab in Patients with Recurrent Respiratory Papillomatosis
A Consensus Statement on the Administration of Systemic Bevacizumab in Patients with Recurrent Respiratory Papillomatosis Open
Objective To provide detailed guidance on the administration of systemic bevacizumab in patients with recurrent respiratory papillomatosis (RRP) based on a detailed review of the scientific literature and a consensus of experts with real‐w…
View article: Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling
Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling Open
Objectives Approximately 25% of Americans suffer from laryngopharyngeal reflux (LPR), a disease for which no effective medical therapy exists. Pepsin is a predominant source of damage during LPR and a key therapeutic target. Fosamprenavir …
View article: The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The <scp>IFOS</scp> Consensus
The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The <span>IFOS</span> Consensus Open
Objective The objective of this work was to gather an international consensus group to propose a global definition and diagnostic approach of laryngopharyngeal reflux (LPR) to guide primary care and specialist physicians in the management …
View article: Evaluation of Social Determinants of Health on Dysphagia Care Pathways at a Tertiary Care Facility
Evaluation of Social Determinants of Health on Dysphagia Care Pathways at a Tertiary Care Facility Open
Objectives Limited research exists evaluating the impact of social determinants of health in influencing care pathways for patients with dysphagia. A better understanding of whether these determinants correlate to altered care and resource…
View article: Demographic differences in the treatment of unilateral vocal fold paralysis
Demographic differences in the treatment of unilateral vocal fold paralysis Open
Objective To determine the impact of patient demographics and social determinants of health on treatment pathways for unilateral vocal fold paralysis (UVFP) at a tertiary laryngology clinic. Study design Retrospective medical record review…
View article: Multicenter Development and Validation of the Vocal Cord Paralysis Experience (CoPE), a Patient-Reported Outcome Measure for Unilateral Vocal Fold Paralysis–Specific Disability
Multicenter Development and Validation of the Vocal Cord Paralysis Experience (CoPE), a Patient-Reported Outcome Measure for Unilateral Vocal Fold Paralysis–Specific Disability Open
Importance Unilateral vocal fold paralysis (UVFP) is a common and life-changing complication of cancer, trauma, and an estimated 500 000 head, neck, and chest surgeries performed annually in the US, among other causes (eg, idiopathic). Con…
View article: Oral and Inhaled Fosamprenavir Reverses Pepsin‐Induced Damage in a Laryngopharyngeal Reflux Mouse Model
Oral and Inhaled Fosamprenavir Reverses Pepsin‐Induced Damage in a Laryngopharyngeal Reflux Mouse Model Open
Objective More than 20% of the US population suffers from laryngopharyngeal reflux. Although dietary/lifestyle modifications and alginates provide benefit to some, there is no gold standard medical therapy. Increasing evidence suggests tha…
View article: Analysis of socioeconomic factors in laryngology clinic utilization for treatment of dysphonia
Analysis of socioeconomic factors in laryngology clinic utilization for treatment of dysphonia Open
Objective To evaluate the association between patient socioeconomic and demographic factors and tertiary care utilization for dysphonia in a localized metropolitan area of the American Midwest. Methods Multivariate regression analysis was …
View article: Twenty‐One for 2021: The Most Influential Papers in Laryngology Since 2000
Twenty‐One for 2021: The Most Influential Papers in Laryngology Since 2000 Open
Objectives/Hypothesis To identify the most influential publications in laryngology since 2000. Study Design Modified Delphi process. Methods Samples of laryngologists drawn from editors of leading journals, organization officers, and thoug…
View article: Association of Social Determinants of Health with Time to Diagnosis and Treatment Outcomes in Idiopathic Subglottic Stenosis
Association of Social Determinants of Health with Time to Diagnosis and Treatment Outcomes in Idiopathic Subglottic Stenosis Open
Objectives: To examine whether social determinants of health (SDH) factors are associated with time to diagnosis, treatment selection, and time to recurrent surgical intervention in idiopathic subglottic stenosis (iSGS) patients. Methods: …
View article: Systemic Bevacizumab for Treatment of Respiratory Papillomatosis: International Consensus Statement
Systemic Bevacizumab for Treatment of Respiratory Papillomatosis: International Consensus Statement Open
Objectives/Hypothesis The purpose of this study is to develop consensus on key points that would support the use of systemic bevacizumab for the treatment of recurrent respiratory papillomatosis (RRP), and to provide preliminary guidance s…
View article: Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis
Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis Open
In this cohort study of 810 patients with iSGS, endoscopic dilation, the most popular surgical approach for iSGS, was associated with a higher recurrence rate compared with other procedures. Cricotracheal resection offered the most durable…
View article: Evaluation of the natural history of patients who aspirate
Evaluation of the natural history of patients who aspirate Open
Objectives/Hypothesis The natural clinical progression of aspiration to eventual pulmonary compromise is not well understood. We hypothesized that dietary modification recommendations, Penetration‐Aspiration Scale (PAS) score, and dysphagi…
View article: Effects of deep brain stimulation on vocal fold immobility in Parkinson's disease
Effects of deep brain stimulation on vocal fold immobility in Parkinson's disease Open
STN-DBS may play an important role in the neuromodulation of PD-induced laryngeal dysfunction, including VF mobility. Characterization of these axial symptoms is important when programming and evaluating responsiveness to DBS.