Jonathan M Guy
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Controlled human infection of healthy adults with lyophilized <i>Neisseria lactamica</i> induces asymptomatic, immunogenic nasopharyngeal carriage in the UK and Mali Open
Background Carriage of Neisseria lactamica (Nlac), a harmless nasopharyngeal commensal, correlates inversely with carriage of Neisseria meningitidis (Nmen), a common cause of meningitis and sepsis outbreaks in sub-Saharan Africa. Nasally-a…
View article: Efficacy, immunogenicity, and safety of the live attenuated nasal pertussis vaccine, BPZE1, in the UK: a randomised, placebo-controlled, phase 2b trial using a controlled human infection model with virulent Bordetella pertussis
Efficacy, immunogenicity, and safety of the live attenuated nasal pertussis vaccine, BPZE1, in the UK: a randomised, placebo-controlled, phase 2b trial using a controlled human infection model with virulent Bordetella pertussis Open
ILiAD Biotechnologies.
View article: Controlled human infection model of Neisseria lactamica in late pregnancy investigating mother-to-infant transmission in the UK: a single-arm pilot trial
Controlled human infection model of Neisseria lactamica in late pregnancy investigating mother-to-infant transmission in the UK: a single-arm pilot trial Open
Medical Research Council and National Institute for Health Research Southampton Biomedical Research Centre.
View article: Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial
Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial Open
Wellcome Trust, Medical Research Council, and NIHR Southampton Biomedical Research Centre.
A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage Open
An engineered commensal bacteria with a surface-expressed vaccine target provoked antigen-specific antibodies during pharyngeal carriage in humans.