Andrew Marsh
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View article: Genetic Algorithms for Optimizing Geothermal Systems
Genetic Algorithms for Optimizing Geothermal Systems Open
View article: Analysis of Holography Techniques for Phase Distortion Removal in Extreme Environments.
Analysis of Holography Techniques for Phase Distortion Removal in Extreme Environments. Open
View article: Solid Propellant Scaling Analysis Using Simultaneous Holography and Imaging Pyrometry.
Solid Propellant Scaling Analysis Using Simultaneous Holography and Imaging Pyrometry. Open
View article: CCDC 1952665: Experimental Crystal Structure Determination
CCDC 1952665: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Magic-angle spinning NMR spectroscopy provides insight into the impact of small molecule uptake by G-quartet hydrogels
Magic-angle spinning NMR spectroscopy provides insight into the impact of small molecule uptake by G-quartet hydrogels Open
Compositions, local structures and interactions of medicinally relevant small molecules added to G-quartet hydrogels are characterized using gel-state NMR spectroscopy.
View article: NCPT – managing environmental gains and losses
NCPT – managing environmental gains and losses Open
How a new practical tool enables non-specialists to systematically assess and manage planning and development impacts on natural capital.
View article: Frontispiece: A Tautoleptic Approach to Chiral Hydrogen‐Bonded Supramolecular Tubular Polymers with Large Cavity
Frontispiece: A Tautoleptic Approach to Chiral Hydrogen‐Bonded Supramolecular Tubular Polymers with Large Cavity Open
Tautomerization-induced symmetry breaking in isocytosine heterocycle followed by dimerization, produces two different hydrogen-bonding interfaces pointing in orthogonal directions. With carefully designed bicyclic molecular scaffolds, this…
View article: The Tetrazole Analogue of the Auxin Indole-3-acetic Acid Binds Preferentially to TIR1 and Not AFB5
The Tetrazole Analogue of the Auxin Indole-3-acetic Acid Binds Preferentially to TIR1 and Not AFB5 Open
Indole-3-acetic acid (auxin) is considered one of the cardinal hormones in plant growth and development. It regulates a wide range of processes throughout the plant. Synthetic auxins exploit the auxin-signaling pathway and are valuable as …
View article: A Tautoleptic Approach to Chiral Hydrogen‐Bonded Supramolecular Tubular Polymers with Large Cavity
A Tautoleptic Approach to Chiral Hydrogen‐Bonded Supramolecular Tubular Polymers with Large Cavity Open
A new strategy towards tubular hydrogen‐bonded polymers based on the self‐assembly of isocytosine tautomers in orthogonal directions is proposed and experimentally verified, including by 1 H fast magic‐angle spinning (MAS) solid‐state NMR.…
View article: CH3F5 Bioorganic Chemistry - Molecular Interactions Numerical Problems Class 1
CH3F5 Bioorganic Chemistry - Molecular Interactions Numerical Problems Class 1 Open
Problems class 1 that uses the approach developed by Michael Abrahams (UCL) and Christopher Hunter (Sheffield and Cambridge) to estimate strengths of interactions between molecules
View article: CH3F5 Bioorganic Chemistry - Molecular Interactions Numerical Problem Class 1
CH3F5 Bioorganic Chemistry - Molecular Interactions Numerical Problem Class 1 Open
Problems class 1 that uses the approach developed by Michael Abrahams (UCL) and Christopher Hunter (Sheffield and Cambridge) to estimate strengths of interactions between molecules
View article: CH3F5 Bioorganic Chemistry - Molecular Interactions Numerical Problems Class 2
CH3F5 Bioorganic Chemistry - Molecular Interactions Numerical Problems Class 2 Open
CH3F5 Numerical problems class 2 - extends the approach taken by Abrahams and Hunter in using hydrogen bond scales to estimate strengths of interactions between molecules.
View article: A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment
A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment Open
View article: Coexistence of Distinct Supramolecular Assemblies in Solution and in the Solid State
Coexistence of Distinct Supramolecular Assemblies in Solution and in the Solid State Open
Invited for the cover of this issue is the group of Steven P. Brown at the University of Warwick and collaborators in Italy and the US. The image depicts the transformation (studied by NMR spectroscopy) between small molecule building bloc…
View article: AndrewMarsh_PH_CLAHRC_2Feb2017.pptx
AndrewMarsh_PH_CLAHRC_2Feb2017.pptx Open
A talk to NHS NIHR Collaborative Leadership Applied Health Research and Care West Midlands team, Theme 3 - Prevention and Detection of Diseases, 2 Feb 2017.Why is public health so important? To me? To the University of Warwick and to Co…
View article: Co‐existence of Distinct Supramolecular Assemblies in Solution and in the Solid State
Co‐existence of Distinct Supramolecular Assemblies in Solution and in the Solid State Open
The formation of distinct supramolecular assemblies, including a metastable species, is revealed for a lipophilic guanosine (G) derivative in solution and in the solid state. Structurally different G‐quartet‐based assemblies are formed in …
View article: Fast Magic-Angle Spinning Three-Dimensional NMR Experiment for Simultaneously Probing H—H and N—H Proximities in Solids
Fast Magic-Angle Spinning Three-Dimensional NMR Experiment for Simultaneously Probing H—H and N—H Proximities in Solids Open
A fast magic-angle spinning (MAS, 70 kHz) solid-state NMR experiment is presented that combines 1H Double-Quantum (DQ) and 14N-1H HMQC (Heteronuclear Multiple-Quantum Coherence) pulse-sequence elements, so …
View article: Chemical structures of enoxolone (18β-glycyrrhetinic acid), 18α-glycyrrhetinic acid) and carbenoxolone (18β-glycyrrhetinic acid).
Chemical structures of enoxolone (18β-glycyrrhetinic acid), 18α-glycyrrhetinic acid) and carbenoxolone (18β-glycyrrhetinic acid). Open
Chemical structures of enoxolone (18β-glycyrrhetinic acid), 18α-glycyrrhetinic acid) and carbenoxolone (18β-glycyrrhetinic acid).
View article: Why I love my yoga practice
Why I love my yoga practice Open
contribution for OM Yoga Magazine 2016
View article: Kinetic Characterisation of a Single Chain Antibody against the Hormone Abscisic Acid: Comparison with Its Parental Monoclonal
Kinetic Characterisation of a Single Chain Antibody against the Hormone Abscisic Acid: Comparison with Its Parental Monoclonal Open
A single-chain Fv fragment antibody (scFv) specific for the plant hormone abscisic acid (ABA) has been expressed in the bacterium Escherichia coli as a fusion protein. The kinetics of ABA binding have been measured using surface plasmon re…
View article: Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein
Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein Open
Finding pleiomorphic targets for drugs allows new indications or warnings for treatment to be identified. As test of concept, we applied a new chemical genomics approach to uncover additional targets for the widely prescribed lipid-lowerin…
View article: Unexpected preparation of 1,3-bis(dec-9-en-1-yl)urea
Unexpected preparation of 1,3-bis(dec-9-en-1-yl)urea Open
Attempted route to prepare N-(dec-9-en-1-yl)-2,2,2-trifluoroacetamide 1 using DPPA and undecenylenic acid led to the unexpected preparation of 1,3-bis(dec-9-en-1-yl)urea.
View article: OctylPyrimidopyrimidine
OctylPyrimidopyrimidine Open
Chemdraw structure of dioctyl 2-oxopyrimido[4,5-d] pyrimidin-5(6H)-one and cyclic hexamer
View article: GaceC10 infrared spectrum O=C1C(N=CN2[C@@]3([H])[C@@](OC(C)(C)O4)([H])[C@@]4([H])[C@](COC(CCCCCCCCC)=O)([H])O3)=C2N=C(N)N1
GaceC10 infrared spectrum O=C1C(N=CN2[C@@]3([H])[C@@](OC(C)(C)O4)([H])[C@@]4([H])[C@](COC(CCCCCCCCC)=O)([H])O3)=C2N=C(N)N1 Open
Infrared spectrum solid state acquired with diamond ATR attachment of "GaceC10" sample I-AH-1SMILES O=C1C(N=CN2[C@@]3([H])[C@@](OC(C)(C)O4)([H])[C@@]4([H])[C@](COC(CCCCCCCCC)=O)([H])O3)=C2N=C(N)N1 2',3'-O-Isopropylidene-5'-decanoylg…
View article: I-LM-1-reaction-isocyanate
I-LM-1-reaction-isocyanate Open
Infrared spectrum of reaction mixture dec-9-en-1-ylisocyanate after overnight stir.
View article: I-LM-1A-1HNMR-400MHzOzric_data
I-LM-1A-1HNMR-400MHzOzric_data Open
1H NMR data acquired in CDCl3 of 1,3-bis(dec-9-en-1-yl)urea to allow reprocessing.
View article: CCDC 961279: Experimental Crystal Structure Determination
CCDC 961279: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Scheme 1 - Curtius rearrangement literature conditions
Scheme 1 - Curtius rearrangement literature conditions Open
Scheme 1 - literature conditions for Curtius rearrangement and subsequent TFA addition.
View article: I-LM-1A_HRMS
I-LM-1A_HRMS Open
High resolution accurate mass measurement of the purified product from treatmenrt of dec-9-en-1-ylisocyanate intermediate with trifluoroacetic acid to confirm identity.
View article: I-LM-1-after TFA addition
I-LM-1-after TFA addition Open
Addition of trifluoroacetic acid to dec-9-en-1-ylisocyanate from Curtius rearrangement.