Jordi Navarro
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View article: #2382 Effects of a group exercise program supported by audiovisual media on muscle strength of people on maintenance hemodialysis: a pilot study
#2382 Effects of a group exercise program supported by audiovisual media on muscle strength of people on maintenance hemodialysis: a pilot study Open
Background and Aims Patients with chronic kidney disease (CKD) undergoing hemodialysis (HD) often present muscular complications, reducing functional capacity and increasing mortality. Exercise programs during HD sessions with the aid of t…
View article: Trends in Hepatitis C Virus Infection Prevalence Among People With HIV in Spain Over 2 Decades (2002–2023)
Trends in Hepatitis C Virus Infection Prevalence Among People With HIV in Spain Over 2 Decades (2002–2023) Open
Background Hepatitis C virus (HCV) has significantly impacted people with human immunodeficiency virus (HIV). Harm reduction programs, changing transmission patterns, and direct-acting antivirals (DAAs) have profoundly altered HIV/HCV coin…
View article: Induction of Resident Memory CD8<sup>+</sup>T cell Phenotypes to Eliminate the HIV reservoir
Induction of Resident Memory CD8<sup>+</sup>T cell Phenotypes to Eliminate the HIV reservoir Open
Enhancing effective antiviral responses within tissue compartments supporting HIV persistence at the time of antiretroviral therapy interruption will be necessary to limit viral rebound. With the hypothesis that CD8 + tissue resident memor…
View article: Safety, immunogenicity and effect on viral rebound of HTI vaccines combined with a TLR7 agonist in early-treated HIV-1 infection: a randomized, placebo-controlled phase 2a trial
Safety, immunogenicity and effect on viral rebound of HTI vaccines combined with a TLR7 agonist in early-treated HIV-1 infection: a randomized, placebo-controlled phase 2a trial Open
Building on results from the AELIX-002 trial with HIVACAT T-cell immunogen (HTI)-based vaccines, the AELIX-003 (NCT04364035) trial tested the safety of the combination of ChAdOx1.HTI (C) and MVA.HTI (M), with the TLR7 agonist vesatolimod (…
View article: NK cell depletion in bispecific antibody therapy is associated with lack of HIV control after ART interruption
NK cell depletion in bispecific antibody therapy is associated with lack of HIV control after ART interruption Open
HIV infection remains incurable as the virus persists within a latent reservoir of CD4+T cells. Novel approaches to enhance immune responses against HIV are essential for effective control and potential cure of the infection. In…
View article: Rate of hepatitis C reinfection after successful direct-acting antivirals treatment among people who inject drugs in Spain: the LIVERate study
Rate of hepatitis C reinfection after successful direct-acting antivirals treatment among people who inject drugs in Spain: the LIVERate study Open
View article: Estudio teórico de un aire acondicionado solar
Estudio teórico de un aire acondicionado solar Open
La tendencia del incremento de la temperatura global tiene efectos nocivos en la salud. Debido a las altas temperaturas actuales, es necesario la implementación de sistemas de aire acondicionado para garantizar el bienestar y confort de la…
View article: NKG2C and NKG2A coexpression defines a highly functional antiviral NK population in spontaneous HIV control
NKG2C and NKG2A coexpression defines a highly functional antiviral NK population in spontaneous HIV control Open
Elite controllers (ECs), a unique group of people with HIV (PWH), exhibit remarkable control of viral replication in the absence of antiretroviral therapy. In this study, we comprehensively characterized the NK cell repertoire in ECs after…
View article: Steatotic liver disease and HIV: an agenda for 2030
Steatotic liver disease and HIV: an agenda for 2030 Open
View article: Evolving AIDS- and non-AIDS Mortality and Predictors in the PISCIS Cohort of People Living With HIV in Catalonia and the Balearic Islands (Spain), 1998–2020
Evolving AIDS- and non-AIDS Mortality and Predictors in the PISCIS Cohort of People Living With HIV in Catalonia and the Balearic Islands (Spain), 1998–2020 Open
Background Effective antiretroviral therapy (ART) has substantially reduced acquired immunodeficiency syndrome (AIDS)-related deaths, shifting the focus to non-AIDS conditions in people living with human immunodeficiency virus (HIV) (PLWH)…
View article: KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir
KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir Open
Human immunodeficiency virus (HIV) infection induces immunological dysfunction, which limits the elimination of HIV-infected cells during treated infection. Identifying and targeting dysfunctional immune cells might help accelerate the pur…
View article: Impact of very early antiretroviral therapy during acute HIV infection on long-term immunovirological outcomes
Impact of very early antiretroviral therapy during acute HIV infection on long-term immunovirological outcomes Open
The strongest predictors of IR in patients who start ART during AHI are the CD4+/CD8+ ratio pre-ART and INSTI-based ART regimens.
View article: Effectiveness and safety of integrase strand transfer inhibitors in Spain: a prospective real-world study
Effectiveness and safety of integrase strand transfer inhibitors in Spain: a prospective real-world study Open
Introduction Second-generation integrase strand transfer inhibitors (INSTIs) are preferred treatment options worldwide, and dolutegravir (DTG) is the treatment of choice in resource-limited settings. Nevertheless, in some resource-limited …
View article: Correction: Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study
Correction: Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study Open
View article: Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study
Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study Open
View article: Treatment of Aneurysmal Bone Cyst with Endoscopic Resection and Bone Allograft with Platelet-Rich Plasma: A Case Report
Treatment of Aneurysmal Bone Cyst with Endoscopic Resection and Bone Allograft with Platelet-Rich Plasma: A Case Report Open
An aneurysmal bone cyst (ABC) is a rare bone tumor usually observed in long bones. The surgical treatment of this pathology is often related to high recurrence rates, so novel biological techniques can help to enhance tissue regeneration a…
View article: Uncovering the NAFLD burden in people living with HIV from high‐ and middle‐income nations: a meta‐analysis with a data gap from Subsaharan Africa
Uncovering the NAFLD burden in people living with HIV from high‐ and middle‐income nations: a meta‐analysis with a data gap from Subsaharan Africa Open
Introduction Non‐alcoholic fatty liver disease (NAFLD) has become a significant concern among people living with HIV (PLHIV), albeit its burden remains unclear. The primary objective of this systematic review (SR) and meta‐analysis (MA) wa…
View article: Exploratory study of an oral screening dysplasia program for HIV-infected men who have sex with men
Exploratory study of an oral screening dysplasia program for HIV-infected men who have sex with men Open
Background: HIV-infected men who have sex with men (MSM) are at high risk to develop human papilloma virus (HPV)-related oropharyngeal cancer. The aim of our study was to assess the usefulness of a pilot oral dysplasia screening program an…
View article: Impact of tenofovir on SARS-CoV-2 infection and severe outcomes among people living with HIV: a propensity score-matched study
Impact of tenofovir on SARS-CoV-2 infection and severe outcomes among people living with HIV: a propensity score-matched study Open
Background Reports on the impact of some antiretrovirals against SARS-CoV-2 infection and disease severity are conflicting. Objectives We evaluated the effect of tenofovir as either tenofovir alafenamide/emtricitabine (TAF/FTC) or tenofovi…
View article: Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response
Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response Open
Human immunodeficiency virus (HIV) establishes a persistent infection in heterogeneous cell reservoirs, which can be maintained by different mechanisms including cellular proliferation, and represent the main obstacle to curing the infecti…
View article: Author response: Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response
Author response: Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response Open
Article Figures and data Abstract Editor's evaluation Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Human immunodeficiency…
View article: Identification of HIV-Reservoir Cells with Reduced Susceptibility to Antibody-Dependent Immune Response
Identification of HIV-Reservoir Cells with Reduced Susceptibility to Antibody-Dependent Immune Response Open
HIV establishes a persistent infection in heterogeneous cell reservoirs, which can be maintained by different mechanisms including cellular proliferation, and represent the main obstacle to curing the infection. The expression of the Fcγ r…
View article: Epidemiological trends of HIV/HCV coinfection in Spain, 2015–2019
Epidemiological trends of HIV/HCV coinfection in Spain, 2015–2019 Open
Objectives We assessed the prevalence of anti‐hepatitis C virus (HCV) antibodies and active HCV infection (HCV‐RNA‐positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies perf…
View article: Induction of Resident Memory CD8 <sup> </sup>T Cell Phenotypes to Eliminate the HIV Reservoir
Induction of Resident Memory CD8 <sup> </sup>T Cell Phenotypes to Eliminate the HIV Reservoir Open
View article: Sociodemographic, clinical, and immunological factors associated with SARS-CoV-2 diagnosis and severe COVID-19 outcomes in people living with HIV: a retrospective cohort study
Sociodemographic, clinical, and immunological factors associated with SARS-CoV-2 diagnosis and severe COVID-19 outcomes in people living with HIV: a retrospective cohort study Open
View article: Strategies to reengage patients lost to follow up in HIV care in high income countries, a scoping review
Strategies to reengage patients lost to follow up in HIV care in high income countries, a scoping review Open
View article: Peripheral and lung resident memory T cell responses against SARS-CoV-2
Peripheral and lung resident memory T cell responses against SARS-CoV-2 Open
View article: HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients
HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients Open
View article: Peripheral and lung resident T cell responses against SARS-CoV-2
Peripheral and lung resident T cell responses against SARS-CoV-2 Open
Considering that SARS-CoV-2 interacts with the host at the respiratory tract mucosal interface, T cells strategically placed within these surfaces, namely resident memory T cells, will be essential to limit viral spread and disease. Import…
View article: Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects Open