Jonathan Oakes
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View article: Effects of early human immunodeficiency virus infection on cerebral white matter blood flow autoregulation
Effects of early human immunodeficiency virus infection on cerebral white matter blood flow autoregulation Open
Blood flow autoregulation in cerebral white matter was measured before and after acute nicardipine-induced changes in mean arterial pressure of 10-21% in 21 treatment naïve HIV-positive adults and 32 controls. The autoregulatory index (-% …
View article: Reduction in cerebral oxygen metabolism in subcortical regions may be a biomarker of cognitive decline in people living with human immunodeficiency virus
Reduction in cerebral oxygen metabolism in subcortical regions may be a biomarker of cognitive decline in people living with human immunodeficiency virus Open
BACKGROUND AND PURPOSE: Regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO2 ) in whole brain, white matter, gray matter and lenticular nuclei were studied in people living with human immunodeficiency virus (PLHIV) as well as …
View article: Usefulness of lumbar puncture educational videos for older people with HIV
Usefulness of lumbar puncture educational videos for older people with HIV Open
Video-based education offers opportunities to enhance patients' medical literacy and to reduce anxiety and hesitation for patients undergoing diagnostic procedures such as lumbar puncture (LP). Multiple studies centered on LP education hav…
View article: Usefulness of lumbar puncture educational videos for older people with HIV
Usefulness of lumbar puncture educational videos for older people with HIV Open
Background Video-based education offers opportunities to enhance patients' medical literacy and to reduce anxiety and hesitation for patients undergoing diagnostic procedures such as lumbar puncture (LP). Multiple studies centered on LP ed…
View article: HepB-CpG vs HepB-Alum Vaccine in People With HIV and Prior Vaccine Nonresponse
HepB-CpG vs HepB-Alum Vaccine in People With HIV and Prior Vaccine Nonresponse Open
Importance Nonresponse to hepatitis B vaccine is common among people with HIV, resulting in vulnerability to infection with hepatitis B virus (HBV). Objective To compare the seroprotection response achieved with a 2-dose (noninferiority, 1…
View article: A longitudinal study of olfactory dysfunction and parosmia in mild COVID-19 cases
A longitudinal study of olfactory dysfunction and parosmia in mild COVID-19 cases Open
Background: COVID-19-related olfactory dysfunction (OD) can persist long after patients recover from acute infection, yet few studies have investigated the long-term progression of this complication. Moreover, existing studies are focused …
View article: Effects of early human immunodeficiency virus infection on cerebral white matter blood flow autoregulation
Effects of early human immunodeficiency virus infection on cerebral white matter blood flow autoregulation Open
Blood flow autoregulation in cerebral white matter was measured before and after acute nicardipine-induced changes in mean arterial pressure of 10–21% in 21 treatment naïve HIV-positive adults and 32 controls. The autoregulatory index (−% …
View article: Reduction in cerebral oxygen metabolism in subcortical regions may be a biomarker of cognitive decline in people living with human immunodeficiency virus
Reduction in cerebral oxygen metabolism in subcortical regions may be a biomarker of cognitive decline in people living with human immunodeficiency virus Open
Background and purpose Regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO 2 ) in whole brain, white matter, gray matter and lenticular nuclei were studied in people living with human immunodeficiency virus (PLHIV) as well as …
View article: COVID-19 related olfactory dysfunction prevalence and natural history in ambulatory patients
COVID-19 related olfactory dysfunction prevalence and natural history in ambulatory patients Open
Background: Evidence regarding prevalence of COVID-19 related Olfactory dysfunction (OD) among ambulatory patients is highly variable due to heterogeneity in study population and measurement methods. Relatively few studies have longitudina…
View article: Autoregulation of White Matter Cerebral Blood Flow to Arterial Pressure Changes in Normal Subjects.
Autoregulation of White Matter Cerebral Blood Flow to Arterial Pressure Changes in Normal Subjects. Open
Endothelial dysfunction causing impaired cerebrovascular vasodilatory capacity in response to reduced blood pressure has been proposed as a mechanism of white matter (WM) disease development. This study investigated autoregulation of CBF t…
View article: Increased Cortical Cerebral Blood Flow in Asymptomatic Human Immunodeficiency Virus-Infected Subjects
Increased Cortical Cerebral Blood Flow in Asymptomatic Human Immunodeficiency Virus-Infected Subjects Open
Human Immunodeficiency Virus (HIV) infected individuals are at high risk for ischemic stroke. To investigate the physiological basis for this risk, we used magnetic resonance imaging (MRI) to measure oxygen extraction fraction (OEF) and ce…