Jonathan Chang
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View article: The C9ORF72 repeat expansion alters neurodevelopment
The C9ORF72 repeat expansion alters neurodevelopment Open
Genetic mutations that cause adult-onset neurodegenerative diseases are often expressed during embryonic stages, but it is unclear whether they alter neurodevelopment and how this might influence disease onset. Here, we show that the most …
View article: Prenatal treprostinil reduces the pulmonary hypertension phenotype in the rat model of congenital diaphragmatic hernia
Prenatal treprostinil reduces the pulmonary hypertension phenotype in the rat model of congenital diaphragmatic hernia Open
United Therapeutics Corporation provided treprostinil and financial support (ISS-2020-10879).
View article: Perception Robustness Testing at Different Levels of Generality
Perception Robustness Testing at Different Levels of Generality Open
Ensuring the success and safety of deployed robotic systems often requires predicting their behavior in a wide range of conditions, precluding practical testing of the physical system itself. We introduce an approach to predict the robustn…
View article: Multitask Prompted Training Enables Zero-Shot Task Generalization
Multitask Prompted Training Enables Zero-Shot Task Generalization Open
Large language models have recently been shown to attain reasonable zero-shot generalization on a diverse set of tasks (Brown et al., 2020). It has been hypothesized that this is a consequence of implicit multitask learning in language mod…
View article: Using Self Organizing Maps to Compare Sepsis Patients from the Neonatal and Adult Intensive Care Unit.
Using Self Organizing Maps to Compare Sepsis Patients from the Neonatal and Adult Intensive Care Unit. Open
Neonatal sepsis, a blood infection occurring in infants younger than 90 days old, represents a significant source of mortality and morbidity among infants.1 Mortality rates increase with postnatal age and can be as high as 52% (36% in newb…
View article: Using Unsupervised Clustering to Identify Pregnancy Co-Morbidities.
Using Unsupervised Clustering to Identify Pregnancy Co-Morbidities. Open
Absent a priori knowledge, unsupervised techniques identify meaningful clusters that can form the basis for subsequent analyses. This study explored the problem of inferring comorbidity-based profiles of complex diseases through unsupervis…
View article: Comparing Apples and Oranges: Off-Road Pedestrian Detection on the NREC Agricultural Person-Detection Dataset
Comparing Apples and Oranges: Off-Road Pedestrian Detection on the NREC Agricultural Person-Detection Dataset Open
Person detection from vehicles has made rapid progress recently with the advent of multiple highquality datasets of urban and highway driving, yet no large-scale benchmark is available for the same problem in off-road or agricultural envir…
View article: Learning Representations of Emotional Speech with Deep Convolutional Generative Adversarial Networks
Learning Representations of Emotional Speech with Deep Convolutional Generative Adversarial Networks Open
Automatically assessing emotional valence in human speech has historically been a difficult task for machine learning algorithms. The subtle changes in the voice of the speaker that are indicative of positive or negative emotional states a…