Jonathan Passeri
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View article: Severe Mitral Regurgitation in Paradoxical Low-Flow, Low-Gradient Severe Aortic Stenosis
Severe Mitral Regurgitation in Paradoxical Low-Flow, Low-Gradient Severe Aortic Stenosis Open
BACKGROUND: Patients with paradoxical low-flow, low-gradient severe aortic stenosis exhibit low transvalvular flow rate (Q), while maintaining preserved left ventricular ejection fraction. Severe mitral regurgitation (MR) also causes a low…
View article: Severe Mitral Regurgitation in Paradoxical Low-Flow Low-Gradient Severe Aortic Stenosis
Severe Mitral Regurgitation in Paradoxical Low-Flow Low-Gradient Severe Aortic Stenosis Open
Background Patients with paradoxical low-flow, low-gradient severe aortic stenosis (LFLGAS) exhibit low transvalvular flow rate (Q), while maintaining preserved left ventricular ejection fraction (LVEF). Concomitant severe mitral regurgita…
View article: Transfemoral tricuspid valve replacement and one-year outcomes: the TRISCEND study
Transfemoral tricuspid valve replacement and one-year outcomes: the TRISCEND study Open
Background and Aims For patients with symptomatic, severe tricuspid regurgitation (TR), early results of transcatheter tricuspid valve (TV) intervention studies have shown significant improvements in functional status and quality of life a…
View article: Impact of Moderate Aortic Stenosis in Patients With Heart Failure With Reduced Ejection Fraction
Impact of Moderate Aortic Stenosis in Patients With Heart Failure With Reduced Ejection Fraction Open
In patients with HFrEF, moderate AS is associated with increased rates of HF hospitalization and mortality. Further investigation is warranted to determine whether AVR in this population improves clinical outcomes.
View article: Severity of and Recovery From Anemia After Transcatheter Aortic Valve Replacement: An Analysis of the PARTNER Trials and Registries
Severity of and Recovery From Anemia After Transcatheter Aortic Valve Replacement: An Analysis of the PARTNER Trials and Registries Open
In patients undergoing TAVR, moderate-to-severe anemia is independently associated with increased 1-year mortality, and recovery from anemia after TAVR is associated with favorable outcomes. Further efforts are needed to determine whether …
View article: Association Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes
Association Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes Open
In patients with severe aortic stenosis and LVEF less than 50%, 1 in 3 experience LVEF improvement within 1 month after TAVR. Early LVEF improvement is associated with lower 5-year all-cause and cardiac death.
View article: Patient‐ and Process‐Related Contributors to the Underuse of Aortic Valve Replacement and Subsequent Mortality in Ambulatory Patients With Severe Aortic Stenosis
Patient‐ and Process‐Related Contributors to the Underuse of Aortic Valve Replacement and Subsequent Mortality in Ambulatory Patients With Severe Aortic Stenosis Open
Background Many patients with severe aortic stenosis (AS) and an indication for aortic valve replacement (AVR) do not undergo treatment. The reasons for this have not been well studied in the transcatheter AVR era. We sought to determine h…
View article: Impact of Decision Aid on Decision-making of Patients With Severe Aortic Stenosis: Randomized Pilot Study
Impact of Decision Aid on Decision-making of Patients With Severe Aortic Stenosis: Randomized Pilot Study Open
The study exceeded enrollment targets, indicating feasibility. Results suggest the American College of Cardiology's DA improved patient knowledge and communication scores. Patients who met with both members of the HVT reported higher SDM. …
View article: Serial measurement of global longitudinal strain among women with breast cancer treated with proton radiation therapy
Serial measurement of global longitudinal strain among women with breast cancer treated with proton radiation therapy Open
Background Conventional photon radiotherapy (RT) for breast cancer is associated with reduction in global longitudinal strain (GLS), an increase in both troponin and N-terminal pro-B type natriuretic peptide (NT-proBNP), and incident heart…
View article: A Left Atrial Mitral Valve Chord
A Left Atrial Mitral Valve Chord Open
A 77-year-old patient presented with a mobile structure on the anterior mitral valve leaflet and was diagnosed with endocarditis. Subsequent imaging demonstrated this finding was consistent with a left atrial mitral valve chord. Recognitio…
View article: Association of Pulmonary Hypertension With Clinical Outcomes of Transcatheter Mitral Valve Repair
Association of Pulmonary Hypertension With Clinical Outcomes of Transcatheter Mitral Valve Repair Open
These findings suggest that pHTN is associated with increased mortality and readmission for heart failure in patients undergoing TMVr using the MitraClip system for severe mitral regurgitation. Further efforts are needed to determine wheth…
View article: Ventricular stroke work and vascular impedance refine the characterization of patients with aortic stenosis
Ventricular stroke work and vascular impedance refine the characterization of patients with aortic stenosis Open
High left ventricular stroke work and low vascular impedance predict better quality of life after valve intervention in patients with aortic stenosis.
View article: Phase II Study of Proton Beam Radiation Therapy for Patients With Breast Cancer Requiring Regional Nodal Irradiation
Phase II Study of Proton Beam Radiation Therapy for Patients With Breast Cancer Requiring Regional Nodal Irradiation Open
PURPOSE To evaluate the safety and efficacy of proton beam radiation therapy (RT) for patients with breast cancer who require regional nodal irradiation. METHODS Patients with nonmetastatic breast cancer who required postoperative RT to th…
View article: Minimally Invasive Non-Resectional Mitral Valve Repair for Degenerative Mitral Regurgitation can be Performed with Excellent Outcomes and Durability
Minimally Invasive Non-Resectional Mitral Valve Repair for Degenerative Mitral Regurgitation can be Performed with Excellent Outcomes and Durability Open
Objective: To review the efficacy of a minimally invasive surgical technique for mitral valve (MV) repair, we reviewed our institutional experience using a non-resectional technique for degenerative mitral regurgitation (DMR). Methods: A r…
View article: ACC/AATS/AHA/ASE/EACTS/HVS/SCA/SCAI/SCCT/SCMR/STS 2017 Appropriate use criteria for the treatment of patients with severe aortic stenosis
ACC/AATS/AHA/ASE/EACTS/HVS/SCA/SCAI/SCCT/SCMR/STS 2017 Appropriate use criteria for the treatment of patients with severe aortic stenosis Open
The American College of Cardiology collaborated with the American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Valve Society, So…
View article: Metabolite Profiles Predict Acute Kidney Injury and Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement
Metabolite Profiles Predict Acute Kidney Injury and Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement Open
Background Acute kidney injury ( AKI ) occurs commonly after transcatheter aortic valve replacement ( TAVR ) and is associated with markedly increased postoperative mortality. We previously identified plasma metabolites predictive of incid…