Jacob Rosenberg
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View article: Extended mesenteric resection in Crohn’s disease: EXCEED Study Protocol—a blinded multicenter randomized controlled clinical trial (RCT)
Extended mesenteric resection in Crohn’s disease: EXCEED Study Protocol—a blinded multicenter randomized controlled clinical trial (RCT) Open
ClinicalTrials.gov NCT06324838. Registered on 04/02/2024.
View article: Mesh placement and the risk of recurrence and ileus in primary ventral hernia repair: A systematic review and network meta-analysis
Mesh placement and the risk of recurrence and ileus in primary ventral hernia repair: A systematic review and network meta-analysis Open
No differences in recurrence rates were observed among the anatomic layers of mesh placements. The results suggest that the increasing use of retromuscular and preperitoneal mesh placements is not supported by strong comparative evidence. …
View article: Nutritional treatment after discharge of older patients at nutritional risk: A single-arm feasibility study
Nutritional treatment after discharge of older patients at nutritional risk: A single-arm feasibility study Open
Summary: Background: Malnutrition is common among older hospitalized patients and is linked to poor outcomes. While the transition between healthcare sectors is important for ensuring adequate nutrition, nutritional interventions have not …
View article: Slowly absorbable sutures do not increase the risk of reoperation for recurrence compared with nonabsorbable sutures in primary ventral hernia repair: A nationwide register-based cohort study
Slowly absorbable sutures do not increase the risk of reoperation for recurrence compared with nonabsorbable sutures in primary ventral hernia repair: A nationwide register-based cohort study Open
Slowly absorbable sutures did not increase the risk of reoperation compared with nonabsorbable sutures, regardless of mesh use. Although no significant difference was found between nonabsorbable and fast-absorbable sutures, this should be …
View article: Mesh Weight in Reoperation for Recurrence After Laparoscopic Inguinal Hernia Repair
Mesh Weight in Reoperation for Recurrence After Laparoscopic Inguinal Hernia Repair Open
Importance Previous studies on mesh weights have focused on the definitions of lightweight and heavyweight meshes, which were not based on clinical outcomes. Objective To investigate which mesh weight would be associated with the lowest re…
View article: Neoadjuvant Chemotherapy for High-risk Localized Upper Tract Urothelial Carcinoma: Final Long-term Outcomes from a Phase 2 Clinical Trial and an Expanded Cohort
Neoadjuvant Chemotherapy for High-risk Localized Upper Tract Urothelial Carcinoma: Final Long-term Outcomes from a Phase 2 Clinical Trial and an Expanded Cohort Open
We previously reported results from a prospective, multicenter, phase 2 trial that demonstrated a pathologic response rate (<ypT2N0) of 63% among 57 patients with high-risk nonmetastatic upper tract urothelial carcinoma (UTUC) treated with…
View article: Redefining Success in Hernia Surgery: The Case for Patient-Reported Outcomes
Redefining Success in Hernia Surgery: The Case for Patient-Reported Outcomes Open
In elective hernia surgery, the primary aim is to improve quality of life, rather than to save life. Therefore, outcome measures should emphasize domains such as pain, function, and overall satisfaction. While some principles also apply to…
View article: A prospective cohort study of the rectal microbiome in patients with suspected appendicitis
A prospective cohort study of the rectal microbiome in patients with suspected appendicitis Open
NCT03349814 (clinicaltrials.gov).
View article: Interventions for anal canal intraepithelial neoplasia
Interventions for anal canal intraepithelial neoplasia Open
All included studies focused on people living with HIV. This may limit the applicability of the results to HIV-negative people. We assessed the certainty of evidence as very low for all outcomes across all nine comparisons, highlighting a …
View article: Management of Adult Groin Hernia in Denmark: a National Updated Consensus
Management of Adult Groin Hernia in Denmark: a National Updated Consensus Open
This article presents the updated Danish national recommendations for the treatment of groin hernias, developed by the Danish Hernia Database steering committee and based on consensus. In alignment with the 2023 European Hernia Society gui…
View article: Use of Dupilumab to Manage Antibody-Drug Conjugate–Induced Cutaneous Toxicities
Use of Dupilumab to Manage Antibody-Drug Conjugate–Induced Cutaneous Toxicities Open
This case series examines the effectiveness of dupilumab as a steroid-sparing therapy among patients with antibody-drug conjugate–related cutaneous toxicities.
View article: Extended Mesenteric Resection in Crohn's Disease: EXCEED Study Protocol - a blinded multicenter randomized controlled clinical trial (RCT)
Extended Mesenteric Resection in Crohn's Disease: EXCEED Study Protocol - a blinded multicenter randomized controlled clinical trial (RCT) Open
Background Crohn's disease presents a persistent challenge, particularly concerning disease recurrence in patients after previous intestinal resection. This recurrence often necessitates additional medical treatment or surgery, imposing a …
View article: Rethinking surgical success in non-cancer operations—why patient experience must lead
Rethinking surgical success in non-cancer operations—why patient experience must lead Open
Background Traditionally, surgical success in non-cancer operations, such as elective hernia repair, has been defined by clinical outcomes, including recurrence and complication rates. However, these measures do not capture the primary rea…
View article: Psychosocial Challenges After Treatment for Colorectal and Anal Cancer: A Descriptive Study
Psychosocial Challenges After Treatment for Colorectal and Anal Cancer: A Descriptive Study Open
Receiving a diagnosis of cancer can profoundly impact an individual's perception of life. It can significantly affect their daily functioning because of changes in work ability, treatment‐related sequelae, and psychological distress. This …
View article: ChatGPT‐4o Compared With Human Researchers in Writing Plain‐Language Summaries for Cochrane Reviews: A Blinded, Randomized Non‐Inferiority Controlled Trial
ChatGPT‐4o Compared With Human Researchers in Writing Plain‐Language Summaries for Cochrane Reviews: A Blinded, Randomized Non‐Inferiority Controlled Trial Open
Introduction Plain language summaries in Cochrane reviews are designed to present key information in a way that is understandable to individuals without a medical background. Despite Cochrane's author guidelines, these summaries often fail…
View article: Patient Reflections on Participation in a Randomised Controlled Multimodal Prehabilitation Trial Before Ventral Hernia Repair
Patient Reflections on Participation in a Randomised Controlled Multimodal Prehabilitation Trial Before Ventral Hernia Repair Open
Background: The aim was to explore patients’ reflections related to their choice of participating or not in a multimodal prehabilitation randomised controlled trial (RCT) in relation to minor surgery. Methods: A qualitative study with 22 s…
View article: Surgeon experience increases nerve identification during Lichtenstein hernia repair: a nationwide register-based study
Surgeon experience increases nerve identification during Lichtenstein hernia repair: a nationwide register-based study Open
An annual surgical volume of ≥30 repairs improved nerve identification rates, reflecting the importance of maintaining continuous experience to enhance familiarity with the surgical field in open inguinal hernia repair.
View article: Risk of reoperation after TEP, TAPP, and Lichtenstein repair for primary groin hernia: a register-based cohort study across two nations
Risk of reoperation after TEP, TAPP, and Lichtenstein repair for primary groin hernia: a register-based cohort study across two nations Open
Purpose Annually, more than 24,000 groin hernia repairs are performed in Sweden and Denmark, approximately 12,000 of which are laparoscopic like totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) repairs. TEP is the pref…
View article: Effect of tailored, intensive prehabilitation for risky lifestyles before ventral hernia repair on postoperative outcomes, health, and costs – study protocol for a randomised controlled trial (STRONG-Hernia)
Effect of tailored, intensive prehabilitation for risky lifestyles before ventral hernia repair on postoperative outcomes, health, and costs – study protocol for a randomised controlled trial (STRONG-Hernia) Open
Background A substantial untapped potential for risk reduction may be fulfilled by applying intensive lifestyle interventions targeting the co-existing risky lifestyle factors Smoking, Nutrition (both malnutrition and obesity), risky Alcoh…
View article: Patient Experiences and Expectations Regarding Erectile Dysfunction Education Prior to Rectal Cancer Surgery: A Qualitative Study
Patient Experiences and Expectations Regarding Erectile Dysfunction Education Prior to Rectal Cancer Surgery: A Qualitative Study Open
Erectile dysfunction is common after surgery for rectal cancer with a prevalence of moderate to severe erectile dysfunction up to 35%. Preservation of sexual function is regarded as a core outcome in colorectal surgery. We wanted to invest…
View article: Reoperation for Recurrence After Groin Hernia Repair in Adolescents: A Nationwide Register‐Based Cohort Study
Reoperation for Recurrence After Groin Hernia Repair in Adolescents: A Nationwide Register‐Based Cohort Study Open
Background Although mesh‐based repairs are used in adults to reduce the risk of recurrence, their necessity in adolescents remains debated. Nonmesh repairs are often preferred in younger patients to avoid potential long‐term complications,…
View article: Rectus abdominis muscle atrophy, prophylactic mesh, and stoma placement: retrospective findings from a prospective multicenter trial
Rectus abdominis muscle atrophy, prophylactic mesh, and stoma placement: retrospective findings from a prospective multicenter trial Open
Purpose The primary aim of this study was to investigate whether rectus abdominis muscle atrophy is associated with a lower risk of developing parastomal hernia. Secondary objectives were to assess whether the use of prophylactic mesh is a…
View article: Researcher's Guide for the Preparation of Tables
Researcher's Guide for the Preparation of Tables Open
Almost all scientific articles include tables, but there is little guidance on how to prepare tables. Authors should enhance the focus on the tables' data-ink, the essential information, and minimizing the no-data-ink, nonessential element…
View article: Chronic pain and foreign body sensation based on mesh placement in primary ventral hernia repair: a systematic review highlighting the evidence gap and a call to action
Chronic pain and foreign body sensation based on mesh placement in primary ventral hernia repair: a systematic review highlighting the evidence gap and a call to action Open
Purpose This systematic review aimed to investigate differences in chronic pain and foreign body sensation based on mesh placement, with recurrence as a secondary outcome. Methods The review was registered in PROSPERO (ID: CRD42024592114),…
View article: Cochrane reviews received more online attention than other systematic reviews—except when published in leading medical journals
Cochrane reviews received more online attention than other systematic reviews—except when published in leading medical journals Open
Traditional bibliometric analyses focus on citation counts, co-authorships, and impact factors, which do not fully capture the real-world impact of an academic publication. An alternative is to consider metrics gathered by Altmetric, which…