Jonathan Rychen
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View article: Minimally invasive approaches using virtual reality planning in elective aneurysm surgery
Minimally invasive approaches using virtual reality planning in elective aneurysm surgery Open
Introduction While endovascular treatment has gained popularity for its minimally invasive approach, microsurgical clipping for unruptured intracranial aneurysms (UIAs) has also evolved using surgical adjuncts such as virtual reality (VR) …
View article: Pial collateral shift after unilateral bypass in bilateral moyamoya disease: illustrative cases
Pial collateral shift after unilateral bypass in bilateral moyamoya disease: illustrative cases Open
BACKGROUND Bilateral revascularization surgery is commonly performed in patients with bilateral moyamoya disease (MMD), even when ischemic symptoms or strokes are confined to one hemisphere. However, in select cases, a unilateral bypass ma…
View article: Exoscopic Clipping of a Superior Cerebellar Artery Aneurysm via a One-Piece Orbitozygomatic Approach: Educational Operative Video
Exoscopic Clipping of a Superior Cerebellar Artery Aneurysm via a One-Piece Orbitozygomatic Approach: Educational Operative Video Open
Superior cerebellar artery (SCA) aneurysms are rare. They represent 1%-2% of all intracranial aneurysms and are usually treated endovascularly.1 However, when the aneurysm configuration is not optimal for endovascular treatment, microsurgi…
View article: Feasibility of robotic posterior fossa skull base surgery
Feasibility of robotic posterior fossa skull base surgery Open
OBJECTIVE Despite its potential advantages, robotic surgery has yet to be applied to skull base procedures. Complex anatomy and restricted access have limited the development of robotic skull base surgery. The authors’ aim was to conduct a…
View article: Assessment of Interrater Reliability and Accuracy of Cerebral Aneurysm Morphometry Using 3D Virtual Reality, 2D Digital Subtraction Angiography, and 3D Reconstruction: A Randomized Comparative Study
Assessment of Interrater Reliability and Accuracy of Cerebral Aneurysm Morphometry Using 3D Virtual Reality, 2D Digital Subtraction Angiography, and 3D Reconstruction: A Randomized Comparative Study Open
Background/Objectives: Detailed morphometric analysis of an aneurysm and the related vascular bifurcation are critical factors when determining rupture risk and planning treatment for unruptured intracranial aneurysms (UIAs). The standard …
View article: Robot-assisted Neuroendoscopy: Surgeon’s Third Hand – a Proof of Concept Study
Robot-assisted Neuroendoscopy: Surgeon’s Third Hand – a Proof of Concept Study Open
In neuroendoscopy, an assistant surgeon holds the endoscope while the operating surgeon performs brain surgery using surgical instruments in both hands. The assistant surgeon’s task can be strenuous over time, especially in long surgeries,…
View article: Supramarginal resection of skull base chordomas: proof of concept and preliminary outcomes
Supramarginal resection of skull base chordomas: proof of concept and preliminary outcomes Open
OBJECTIVE The mainstay of treatment for skull base chordoma (SBC) is maximal safe resection followed by radiotherapy. However, even after gross-total resection (GTR), the recurrence rate is high due to microscopic disease in the resection …
View article: Fulminant hemorrhagic course of a thalamic H3 K27-altered diffuse midline glioma in an adult patient: illustrative case
Fulminant hemorrhagic course of a thalamic H3 K27-altered diffuse midline glioma in an adult patient: illustrative case Open
BACKGROUND H3 K27-altered diffuse midline gliomas (DMGs) are rare tumors, which are, regardless of their histological appearance, classified as World Health Organization grade 4 tumors. They are characterized by a diffuse growth pattern, m…
View article: Perioperative continuation or ultra-early resumption of antithrombotics in elective neurosurgical cranial procedures
Perioperative continuation or ultra-early resumption of antithrombotics in elective neurosurgical cranial procedures Open
OBJECTIVE Discontinuation of antithrombotics (AT) prior to elective cranial procedures is common practice, despite the higher risk of thromboembolic complications in these patients. The aim of this study was to investigate the risks and be…
View article: Supratentorial cerebrospinal fluid diversion using image-guided trigonal ventriculostomy during retrosigmoid craniotomy for cerebellopontine angle tumors
Supratentorial cerebrospinal fluid diversion using image-guided trigonal ventriculostomy during retrosigmoid craniotomy for cerebellopontine angle tumors Open
Background Cerebellar contusion, swelling and herniation is frequently encoutered upon durotomy in patients undergoing retrosigmoid craniotomy for cerebellopontine angle (CPA) tumors, despite using standard methods to obtain adequate cereb…
View article: Hemiparkinsonism caused by a lateral sphenoid wing meningioma, with tractography analysis: illustrative case
Hemiparkinsonism caused by a lateral sphenoid wing meningioma, with tractography analysis: illustrative case Open
BACKGROUND The etiologies of parkinsonism are diverse. A possible and rare cause of hemiparkinsonism is mechanical compression of the basal ganglia and its connecting white matter tracts. The authors present a case of hemiparkinsonism caus…
View article: The sylvian keyhole approach for surgical clipping of middle cerebral artery aneurysms: Technical nuance to the minipterional craniotomy
The sylvian keyhole approach for surgical clipping of middle cerebral artery aneurysms: Technical nuance to the minipterional craniotomy Open
Background The minipterional (MPT) craniotomy is a workhorse approach for clipping of middle cerebral artery (MCA) aneurysms. Because it aims to reach the skull base, traction on the temporal muscle is required. As a result, patients may s…
View article: Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study
Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study Open
Growing evidence suggests that coronavirus disease 2019 (COVID-19) is associated with acute and long-term neurological sequelae. However, the underlying pathophysiological mechanisms resulting in central nervous system (CNS) derogation rem…
View article: Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and signs of neurodegeneration: a prospective cross-sectional study
Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and signs of neurodegeneration: a prospective cross-sectional study Open
Importance Growing evidence suggests that coronavirus disease 2019 (COVID-19) is associated with neurological sequelae. However, the underlying pathophysiological mechanisms resulting in central nervous system (CNS) derogation remain uncle…
View article: Yield of early postoperative computed tomography after frontal ventriculoperitoneal shunt placement
Yield of early postoperative computed tomography after frontal ventriculoperitoneal shunt placement Open
Despite being widely used, ventriculoperitoneal (VP) shunt placement is a procedure often associated with complications and revision surgeries. Many neurosurgical centers routinely perform early postoperative cranial computer tomography (C…
View article: Efficacy and Safety of Fingolimod in an Unselected Patient Population
Efficacy and Safety of Fingolimod in an Unselected Patient Population Open
The efficacy in reducing relapses was comparable to that observed in the phase III trials. In our cohort fingolimod was safe and efficacious irrespective of comorbidities and previous treatment.