Jonathan Santos Apolonio
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View article: Drenagem torácica:
Drenagem torácica: Open
A drenagem torácica é um procedimento médico com finalidade de retirar gases, sangue ou fluídos do espaço pleural de pacientes, em que é necessário recuperar sua expansão pulmonar. Como é geralmente empregada após a ocorrência de traumas q…
View article: Usher syndrome: Genetic diagnosis and current therapeutic approaches
Usher syndrome: Genetic diagnosis and current therapeutic approaches Open
Usher Syndrome (USH) is the most common deaf-blind syndrome, affecting approximately 1 in 6000 people in the deaf population. This genetic condition is characterized by a combination of hearing loss (HL), retinitis pigmentosa, and, in some…
View article: <i>Helicobacter pylori</i> infection in pregnant women: Gastrointestinal symptoms and pregnancy- related disorders
<i>Helicobacter pylori</i> infection in pregnant women: Gastrointestinal symptoms and pregnancy- related disorders Open
Helicobacter pylori (H. Pylori) is a gram-negative, flagellated and spiral-shaped bacterial pathogen that impacts approximately 46% among pregnant women globally and has been associated with various maternal-fetal complications. Iron defic…
View article: Crohn's disease and clinical management today: How it does?
Crohn's disease and clinical management today: How it does? Open
Crohn’s Disease (CD) is an Inflammatory Bowel Disease and is characterized by an immune-mediated nature. Its etiology results from the interaction between genetic, enviromental and microbial factors. Regarding pathophysiology, it involves …
View article: One hundred years of dipyrone (metamizole): the recent evidence on its safety
One hundred years of dipyrone (metamizole): the recent evidence on its safety Open
Dipyrone is a non-opioid analgesic drug used for fever and many types of pain. Due to the risk of induced agranulocytosis, it was banned in the early 1980s in several countries, but is still widely used in Brazil, Mexico, China and others.…
View article: Syndemic aspects between COVID-19 pandemic and social inequalities
Syndemic aspects between COVID-19 pandemic and social inequalities Open
Although the coronavirus disease 2019 (COVID-19) pandemic has reached all over the world population, it has demonstrated a heterogeneous impact on different populations. The most vulnerable communities which coexist daily with the social i…
View article: COVID-19 neuropsychiatric repercussions: Current evidence on the subject
COVID-19 neuropsychiatric repercussions: Current evidence on the subject Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has affected the entire world, causing the coronavirus disease 2019 (COVID-19) pandemic since it was first discovered in Wuhan, China in December 2019. Among the clinic…
View article: Effects of nutrients on immunomodulation in patients with severe COVID-19: Current knowledge
Effects of nutrients on immunomodulation in patients with severe COVID-19: Current knowledge Open
Recent research has demonstrated that critically ill patients with coronavirus disease 2019 (COVID-19) show significant immune system dysregulation. Due to that, some nutrients that influence immunomodulation have been suggested as a form …
View article: Treatment and Drug Resistance to Helicobacter Pylori: A Brief Review
Treatment and Drug Resistance to Helicobacter Pylori: A Brief Review Open
Helicobacter pylori is a gram-negative, spiral-shaped bacterium that inhabits the gastric environment of 60.3% of the global population [1]. Though most individuals infected with the bacterium remain asymptomatic, it is known that this inf…
View article: Extragastric Manifestations of Helicobacter Pylori Infection: A Commentary
Extragastric Manifestations of Helicobacter Pylori Infection: A Commentary Open
Helicobacter pylori (Hp) is characterized as a gram-negative bacterium with microaerophilic metabolism, flagellated and helix-shaped that affects approximately 50% of the world population and, in some regions, this rate can exceed 80% [1,2…
View article: Oncolytic virus therapy in cancer: A current review
Oncolytic virus therapy in cancer: A current review Open
In view of the advancement in the understanding about the most diverse types of cancer and consequently a relentless search for a cure and increased survival rates of cancer patients, finding a therapy that is able to combat the mechanism …
View article: Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs: A literature review
Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs: A literature review Open
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm and was the first neoplastic disease associated with a well-defined genotypic anomaly - the presence of the Philadelphia chromosome. The advances in cytogenetic and molecular …
View article: Treatment of <i>Helicobacter pylori</i> infection in children: A systematic review
Treatment of <i>Helicobacter pylori</i> infection in children: A systematic review Open
View article: Gastric Cancer: A Brief Review, from Risk Factors to Treatment
Gastric Cancer: A Brief Review, from Risk Factors to Treatment Open