Jonathan Shine
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View article: Harmonized Protocol for Segmentation of the Hippocampal Tail on High-Resolution <i>in vivo</i> MRI from the Hippocampal Subfields Group (HSG)
Harmonized Protocol for Segmentation of the Hippocampal Tail on High-Resolution <i>in vivo</i> MRI from the Hippocampal Subfields Group (HSG) Open
The hippocampus is a heterogeneous structure with cytoarchitectonically distinct subfields that exhibit heterogeneous lifespan trajectories and are differentially susceptible to diseases. Advances in high-resolution imaging have accelerate…
View article: Altered Coding of Environmental Boundaries in Human Aging: An <scp>fMRI</scp> Study
Altered Coding of Environmental Boundaries in Human Aging: An <span>fMRI</span> Study Open
Aging is associated with changes in spatial memory and navigation, yet the mechanisms underlying these changes are not yet fully understood. Environmental boundaries are among the most salient and reliable spatial cues, supporting both spa…
View article: Altered coding of environmental boundaries in human aging: an fMRI study
Altered coding of environmental boundaries in human aging: an fMRI study Open
Aging is associated with changes in spatial memory and navigation, yet the mechanisms underlying these changes are not yet fully understood. Environmental boundaries are among the most salient and reliable spatial cues, supporting both spa…
View article: Global and Local Head Direction Coding in the Human Brain
Global and Local Head Direction Coding in the Human Brain Open
Orientation-specific head direction (HD) cells increase their firing rate to indicate one’s facing direction in the environment. Rodent studies suggest HD cells in distinct areas of thalamus and retrosplenial cortex (RSC) code either for g…
View article: Evidence for allocentric boundary and goal direction information in the human entorhinal cortex and subiculum
Evidence for allocentric boundary and goal direction information in the human entorhinal cortex and subiculum Open
In rodents, cells in the medial entorhinal cortex (EC) and subiculum code for the allocentric direction to environment boundaries, which is an important prerequisite for accurate positional coding. Although in humans boundary-related signa…
View article: Increased posterior default mode network activity and structural connectivity in young adult <i>APOE</i>-ε4 carriers: a multi-modal imaging investigation
Increased posterior default mode network activity and structural connectivity in young adult <i>APOE</i>-ε4 carriers: a multi-modal imaging investigation Open
Young adult APOE -ε4 carriers show increased activity in posterior regions of the default mode network (pDMN), but how this is related to structural connectivity is unknown. Thirty young adults (half APOE -ε4 carriers, the other half APOE …
View article: The GridCAT: A Toolbox for Automated Analysis of Human Grid Cell Codes in fMRI
The GridCAT: A Toolbox for Automated Analysis of Human Grid Cell Codes in fMRI Open
Human functional magnetic resonance imaging (fMRI) studies examining the putative firing of grid cells (i.e., the grid code) suggest that this cellular mechanism supports not only spatial navigation, but also more abstract cognitive proces…
View article: The GridCAT: A toolbox for automated analysis of human grid cell codes in fMRI
The GridCAT: A toolbox for automated analysis of human grid cell codes in fMRI Open
Human fMRI studies examining the putative firing of grid cells (i.e., the grid code) suggest that this cellular mechanism supports not only spatial navigation, but also more abstract cognitive processes. This research area, however, remain…
View article: The Human Retrosplenial Cortex and Thalamus Code Head Direction in a Global Reference Frame
The Human Retrosplenial Cortex and Thalamus Code Head Direction in a Global Reference Frame Open
In rodents, head direction (HD) cells signal facing direction in the environment via increased firing when the animal assumes a certain orientation. Distinct brain regions, the retrosplenial cortex (RSC) and thalamus, code for visual and v…
View article: Evidencing a place for the hippocampus within the core scene processing network
Evidencing a place for the hippocampus within the core scene processing network Open
Functional neuroimaging studies have identified several “core” brain regions that are preferentially activated by scene stimuli, namely posterior parahippocampal gyrus (PHG), retrosplenial cortex (RSC), and transverse occipital sulcus (TOS…