Jonathan A C Sterne
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View article: Projecting changes in demographics and causes of death in people with HIV in western Europe from 2025 to 2050: a mathematical modelling study
Projecting changes in demographics and causes of death in people with HIV in western Europe from 2025 to 2050: a mathematical modelling study Open
US National Institute on Alcohol Abuse and Alcoholism and US National Institute of Allergy and Infectious Diseases.
View article: Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England: a retrospective, population-based cohort study using linked electronic health records
Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England: a retrospective, population-based cohort study using linked electronic health records Open
Wellcome Trust, British Heart Foundation Data Science Centre, and Health Data Research UK.
View article: OpenSAFELY: Effectiveness of COVID-19 Vaccination in Children and Adolescents
OpenSAFELY: Effectiveness of COVID-19 Vaccination in Children and Adolescents Open
Background: We assessed the safety and effectiveness of the first- and second-dose BNT162b2 COVID-19 vaccination, offered as part of the national COVID-19 vaccine roll-out from September 2021, in children and adolescents in England. Method…
View article: High-volume day-case hip arthroplasty in a district general hospital
High-volume day-case hip arthroplasty in a district general hospital Open
Aims With the increasing burden of arthroplasty waiting lists within Northern Ireland, this study aims to evaluate the safety, efficacy, and postoperative outcomes following the introduction of a high-volume day-case arthroplasty unit in a…
View article: Transparent reporting of observational studies emulating a target trial: the TARGET Statement
Transparent reporting of observational studies emulating a target trial: the TARGET Statement Open
Importance When randomized trials are unavailable or not feasible, observational studies can be used to answer causal questions about the comparative effects of interventions by attempting to emulate a hypothetical pragmatic randomized tri…
View article: COVID-19 and Respiratory Conditions in Vaccinated and Unvaccinated People
COVID-19 and Respiratory Conditions in Vaccinated and Unvaccinated People Open
ObjectivesTo better understand the long-term respiratory impact of COVID-19, this study aims to determine which respiratory conditions are associated with diagnosed COVID-19 by vaccination status in both hospitalised patients and the gener…
View article: COVID-19 and Neurodegenerative Diseases in Vaccinated and Unvaccinated People
COVID-19 and Neurodegenerative Diseases in Vaccinated and Unvaccinated People Open
ObjectivesTo determine which neurodegenerative diseases and related risk conditions are associated with diagnosed COVID-19 by vaccination status in both hospitalized patients and the general population. To expand on existing literature by …
View article: Handling of missing values in whole-population electronic health records: a simulation study
Handling of missing values in whole-population electronic health records: a simulation study Open
ObjectivesThis study evaluates the scalability of multiple imputation methods, specifically Multivariate Imputation by Chained Equations (MICE), for addressing missing data in whole-population EHRs (Electronic Health Records). We investiga…
View article: The relationship between general practice characteristics, case-mix, and secondary care attendances/admissions before and after the COVID-19 pandemic: Protocol for an OpenSAFELY cohort study
The relationship between general practice characteristics, case-mix, and secondary care attendances/admissions before and after the COVID-19 pandemic: Protocol for an OpenSAFELY cohort study Open
Background Healthcare services in England experience increased pressure during winter months due to seasonal infectious diseases, increased multimorbidity, and fluctuating demand. Understanding how characteristics of general practices, and…
View article: Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records
Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records Open
Background Clinically coded long COVID cases in electronic health records (EHRs) are incomplete, despite reports of rising cases of long COVID. Aim To determine patient characteristics associated with clinically coded long COVID. Design & …
View article: Effect of the 2022 COVID-19 booster vaccination campaign in people aged 50 years in England: Regression discontinuity analysis in OpenSAFELY-TPP
Effect of the 2022 COVID-19 booster vaccination campaign in people aged 50 years in England: Regression discontinuity analysis in OpenSAFELY-TPP Open
SARS-CoV-2 vaccines are highly effective in preventing severe COVID-19 but require boosting to maintain protection. Changes to circulating variants and prevalent natural immunity may impact on real-world effectiveness of boosters. With NHS…
View article: Incidence and outcomes of posterior circulation stroke following traumatic vertebral artery injury: A 6-year single-center retrospective cohort study
Incidence and outcomes of posterior circulation stroke following traumatic vertebral artery injury: A 6-year single-center retrospective cohort study Open
Objectives: Vertebral artery injury (VAI) is an uncommon, but potentially devastating, complication following cervical spine trauma. Posterior circulation ischemia (POCS) can result from a disruption to the vertebral arteries and potential…
View article: UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research
UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research Open
IntroductionThe UK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment (TRE) for the UK's longitudinal research community, supporting the UK's unparalleled collection of Longitudinal Population Studies …
View article: Understanding mechanisms of thrombosis and thrombocytopenia with adenoviral SARS-CoV-2 vaccines: a comprehensive synopsis
Understanding mechanisms of thrombosis and thrombocytopenia with adenoviral SARS-CoV-2 vaccines: a comprehensive synopsis Open
Background Thrombosis with thrombocytopenia syndrome is a rare condition known to occur spontaneously or after heparin use. With the advent of COVID-19 vaccines during the pandemic, thrombosis with thrombocytopenia syndrome cases emerged p…
View article: Cannabis Use and Self-Reported Bothersome Symptoms in People with HIV
Cannabis Use and Self-Reported Bothersome Symptoms in People with HIV Open
Objective: While cannabis use is common among people with HIV (PWH), there have been few studies examining the association of use with health outcomes among PWH. We aimed to evaluate the association between cannabis use and bothersome phys…
View article: Harmonization of alcohol use data and mortality across a multi‐national <scp>HIV</scp> cohort collaboration
Harmonization of alcohol use data and mortality across a multi‐national <span>HIV</span> cohort collaboration Open
Background Alcohol use is measured in diverse ways across settings. Harmonization of measures is necessary to assess effects of alcohol use in multi‐cohort collaborations, such as studies of people with HIV (PWH). Methods Data were combine…
View article: A statement on the ongoing genocide in Gaza
A statement on the ongoing genocide in Gaza Open
Communication, Culture and Critique has been the leading venue for critical approaches to communication and media studies. This issue marks the first guided by a newly formed Editorial Collective, which seeks to rekindle the politically en…
View article: PD49 Developing Evidence-Based Optimal Testing Strategies To Monitor Long-Term Conditions In Primary Care
PD49 Developing Evidence-Based Optimal Testing Strategies To Monitor Long-Term Conditions In Primary Care Open
Introduction Most patients with long-term conditions (LTC) receive regular blood tests to monitor disease progression and response to treatment and to detect complications. There is currently no robust evidence to inform recommendations on…
View article: Sodium–glucose co-transporter-2 inhibitors for hospitalised patients with COVID-19: a prospective meta-analysis of randomised trials
Sodium–glucose co-transporter-2 inhibitors for hospitalised patients with COVID-19: a prospective meta-analysis of randomised trials Open
None.
View article: COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People
COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People Open
Importance Associations have been found between COVID-19 and subsequent mental illness in both hospital- and population-based studies. However, evidence regarding which mental illnesses are associated with COVID-19 by vaccination status in…
View article: Cohort study of cardiovascular safety of different COVID-19 vaccination doses among 46 million adults in England
Cohort study of cardiovascular safety of different COVID-19 vaccination doses among 46 million adults in England Open
The first dose of COVID-19 vaccines led to an overall reduction in cardiovascular events, and in rare cases, cardiovascular complications. There is less information about the effect of second and booster doses on cardiovascular diseases. U…
View article: Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people
Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people Open
UK National Institute for Health and Care Research, UK Research and Innovation (UKRI) Medical Research Council, UKRI Engineering and Physical Sciences Research Council, Health Data Research UK, Diabetes UK, British Heart Foundation, and th…
View article: Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP Open
Background: The UK delivered its first “booster” COVID-19 vaccine doses in September 2021, initially to individuals at high risk of severe disease, then to all adults. The BNT162b2 Pfizer-BioNTech vaccine was used initially, then also Mode…
View article: Discrimination of the Veterans Aging Cohort Study Index 2.0 for Predicting Cause-specific Mortality Among Persons With HIV in Europe and North America
Discrimination of the Veterans Aging Cohort Study Index 2.0 for Predicting Cause-specific Mortality Among Persons With HIV in Europe and North America Open
Background Predicting cause-specific mortality among people with HIV (PWH) could facilitate targeted care to improve survival. We assessed discrimination of the Veterans Aging Cohort Study (VACS) Index 2.0 in predicting cause-specific mort…
View article: OpenSAFELY: Effectiveness of COVID-19 vaccination in children and adolescents
OpenSAFELY: Effectiveness of COVID-19 vaccination in children and adolescents Open
Background Children and adolescents in England were offered BNT162b2 as part of the national COVID-19 vaccine roll out from September 2021. We assessed the safety and effectiveness of first and second dose BNT162b2 COVID-19 vaccination in …
View article: Care interruptions and mortality among adults in Europe and North America
Care interruptions and mortality among adults in Europe and North America Open
Objective: Interruptions in care of people with HIV (PWH) on antiretroviral therapy (ART) are associated with adverse outcomes, but most studies have relied on composite outcomes. We investigated whether mortality risk following care inter…
View article: 9. Beyond Access: Transforming Ableist Techno-Worlds
9. Beyond Access: Transforming Ableist Techno-Worlds Open
Media and disability scholars Neta Alexander and Jonathan Sterne reflect on how they have come to study technology through a disability-informed lens.Grounding this conversation in their own intellectual journeys, they challenge ableist pe…