Jonathan T. Boyd
YOU?
Author Swipe
View article: Improving dual targeting selectivity in T-cell engagers via synapse-gated and affinity-tuned trispecific antibody design
Improving dual targeting selectivity in T-cell engagers via synapse-gated and affinity-tuned trispecific antibody design Open
T-cell engagers (TCEs) represent a powerful drug modality for redirecting a patient's own T cells to recognize and eradicate cancer cells. Although TCEs have been effective in treating hematological cancers, their broad application for sol…
View article: Hypereosinophilic syndrome presents as multifocal acute ischemic strokes: Case series and review
Hypereosinophilic syndrome presents as multifocal acute ischemic strokes: Case series and review Open
Introduction: Hypereosinophilic syndrome (HES) is a rare condition associated with hypereosinophilia and associated with multi-organ damage. HES presents with neurological manifestations such as ischemic strokes, encephalopathy, peripheral…
View article: Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis
Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis Open
Systemic administration of bio-therapeutics can result in only a fraction of drug reaching targeted tissues, with the majority of drug being distributed to tissues irrelevant to the drug’s site of action. Targeted delivery to specific orga…
View article: Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring
Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring Open
Eosinophilic esophagitis (EoE) is diagnosed by symptoms, and at least 15 intraepithelial eosinophils per high power field in an esophageal biopsy. Other pathologic features have not been emphasized. We developed a histology scoring system …