Jonathan Trites
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View article: Oncologic and Functional Outcomes of T3 Glottic Squamous Cell Carcinoma Following Transoral Laser Microsurgery: A Retrospective Chart Review
Oncologic and Functional Outcomes of T3 Glottic Squamous Cell Carcinoma Following Transoral Laser Microsurgery: A Retrospective Chart Review Open
Importance Few centers globally use transoral laser microsurgery (TLM) for primary treatment of T3 glottic squamous cell carcinoma (SCC); consequently, data on its use in this setting are sparse. Objective The aim of this study was to eval…
View article: “Close Then Clear” Margins in Transoral Resection of p16+ Oropharyngeal Squamous Cell Carcinoma
“Close Then Clear” Margins in Transoral Resection of p16+ Oropharyngeal Squamous Cell Carcinoma Open
Objective Standard 5‐mm surgical margins in the oropharynx are challenging due to the intimate relationship with neurovascular structures and patient function. De‐escalation of therapy with the acceptance of close surgical margins may impr…
View article: Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review
Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review Open
Importance There is a limited understanding of anterior commissure (AC) involvement in glottic squamous cell carcinoma (SCC), particularly when comparing T1b, T2a with AC involvement (T2AC), and T2a without AC involvement (T2noAC). Objecti…
View article: Management of positive resection margins following transoral laser microsurgery for glottic cancer
Management of positive resection margins following transoral laser microsurgery for glottic cancer Open
Objectives The current literature provides limited guidance on the management of positive margins (PMs) following transoral laser microsurgery (TLM) for glottic squamous cell carcinoma (SCC). Long‐term data exploring the treatment of PMs w…
View article: The impact of national holidays on postoperative radiotherapy of squamous cell carcinoma of the head and neck
The impact of national holidays on postoperative radiotherapy of squamous cell carcinoma of the head and neck Open
View article: A case report: Primary malignant melanoma of the glottic larynx – A very rare entity
A case report: Primary malignant melanoma of the glottic larynx – A very rare entity Open
Background: Primary mucosal melanoma of the larynx is an extremely rare entity. Our case represents the seventeenth case reported to date globally, and the first Canadian case to be reported. Case presentation: We present the case of a 70-…
View article: Frequency and accuracy of intraoperative bone margin sampling for T4a cancers of the head and neck at the QEII Health Sciences Centre: A retrospective chart review
Frequency and accuracy of intraoperative bone margin sampling for T4a cancers of the head and neck at the QEII Health Sciences Centre: A retrospective chart review Open
Background Stage T4a cancers are associated with a 5-year survival of 21.6–59.0%. Adequate resection of these tumors is a critical factor in maximizing survival. Tumors invading bone pose a unique challenge to intraoperative bone margin as…
View article: Margin Sampling and Survival Outcomes in Oral Cavity and p16‐Positive Oropharyngeal Squamous Cell Carcinoma
Margin Sampling and Survival Outcomes in Oral Cavity and p16‐Positive Oropharyngeal Squamous Cell Carcinoma Open
Objective To compare the association of margin sampling technique on survival outcomes in surgically treated cT1‐2 oral cavity and oropharyngeal squamous cell carcinoma. Study Design A prospective longitudinal cohort study. Setting Tertiar…
View article: Injection laryngoplasty during transoral laser microsurgery for early glottic cancer: A randomized controlled trial
Injection laryngoplasty during transoral laser microsurgery for early glottic cancer: A randomized controlled trial Open
Background Transoral laser microsurgery is widely used for treating T1/T2 glottic cancers. Hyaluronic acid (HA) is commonly used in vocal cord augmentation. We investigated the impact of intra-operative injection laryngoplasty on voice out…
View article: Oncological and functional outcomes following treatment of T1a glottic squamous cell carcinoma with transoral laser microsurgery
Oncological and functional outcomes following treatment of T1a glottic squamous cell carcinoma with transoral laser microsurgery Open
Background Laryngeal cancers of glottic origin comprise a large proportion of head and neck malignancies. Transoral laser microsurgery (TLM) and radiation therapy are mainstays in the treatment of early stage glottic cancer, but debate per…
View article: Management of Peritonsillar Abscesses in Adults: Survey of Otolaryngologists in Canada and the United States
Management of Peritonsillar Abscesses in Adults: Survey of Otolaryngologists in Canada and the United States Open
Objective The management of peritonsillar abscess (PTA) has evolved over time. We sought to define contemporary practice patterns for the diagnosis and treatment of PTA. Study Design Cross‐sectional survey. Setting The 15‐question survey w…
View article: Functional and Oncologic Outcomes of Octogenarians Undergoing Transoral Laser Microsurgery for Laryngeal Cancer
Functional and Oncologic Outcomes of Octogenarians Undergoing Transoral Laser Microsurgery for Laryngeal Cancer Open
Objective To evaluate the oncologic and functional outcomes of transoral laser microsurgery (TLM) for glottic cancers in patients ≥80 years. Study Design Prospectively collected case series. Setting QEII Health Sciences Centre, Halifax, Ca…
View article: Psychosocial Distress in Adult Patients Awaiting Cancer Surgery during the COVID-19 Pandemic
Psychosocial Distress in Adult Patients Awaiting Cancer Surgery during the COVID-19 Pandemic Open
Cancer causes substantial emotional and psychosocial distress, which may be exacerbated by delays in treatment. The COVID-19 pandemic has resulted in increased wait times for many patients with cancer. In this study, the psychosocial distr…
View article: Treatment Choices in Managing Bethesda III and IV Thyroid Nodules: A Canadian Multi‐institutional Study
Treatment Choices in Managing Bethesda III and IV Thyroid Nodules: A Canadian Multi‐institutional Study Open
Objective Patient‐centered decision making is increasingly identified as a desirable component of medical care. To manage indeterminate thyroid nodules, patients are offered the options of surveillance, diagnostic hemithyroidectomy, or mol…
View article: Oral Losartan After Limited Mandibulectomy for Treatment of Desmoid-Type Fibromatosis
Oral Losartan After Limited Mandibulectomy for Treatment of Desmoid-Type Fibromatosis Open
Desmoid-type fibromatosis (DF) is a rare soft tissue lesion with an annual incidence of 2 to 4 per million population and peak incidence occurring at approximately 4.5 years of age. While benign, the tumor has a locally aggressive infiltra…
View article: Specimen oriented intraoperative margin assessment in oral cavity and oropharyngeal squamous cell carcinoma
Specimen oriented intraoperative margin assessment in oral cavity and oropharyngeal squamous cell carcinoma Open
Objective Evaluate the oncologic outcomes and cost analysis of transitioning to a specimen oriented intraoperative margin assessment protocol from a tumour bed sampling protocol in oral cavity (OCSCC) and oropharyngeal squamous cell carcin…
View article: Carbon footprint reduction associated with a surgical outreach clinic
Carbon footprint reduction associated with a surgical outreach clinic Open
Background Healthcare systems generate substantial carbon footprints that may be targeted to decrease greenhouse gas emissions. Outreach clinics may represent tools to assist in this reduction by optimizing patient related travel. Therefor…
View article: The Abscopal Effect in Head-and-Neck Squamous Cell Carcinoma Treated with Radiotherapy and Nivolumab: A Case Report and Literature Review
The Abscopal Effect in Head-and-Neck Squamous Cell Carcinoma Treated with Radiotherapy and Nivolumab: A Case Report and Literature Review Open
Introduction: The abscopal effect is a rarely observed outcome of radiotherapy wherein there is a reduction in metastatic disease burden outside of the targeted treatment area. Likely due to an in situ vaccine effect of radiotherapy, the a…
View article: Needs assessment for a decision support tool in oral cancer requiring major resection and reconstruction: a mixed-methods study protocol
Needs assessment for a decision support tool in oral cancer requiring major resection and reconstruction: a mixed-methods study protocol Open
Introduction Advanced oral cancer and its ensuing treatment engenders significant morbidity and mortality. Patients are often elderly with significant comorbidities. Toxicities associated with surgical resection can be devastating and they…
View article: Tubed Anterolateral Thigh Free Flap for Pharyngoesophageal Reconstruction
Tubed Anterolateral Thigh Free Flap for Pharyngoesophageal Reconstruction Open
Summary: Caustic ingestions can severely injure the upper and lower aerodigestive tract, resulting in detrimental mucosal changes both acutely and chronically. Injuries are most severe following alkaline ingestion. Esophagectomy is often r…
View article: Prospective outcomes following drainless superficial parotidectomy with sternocleidomastoid flap reconstruction
Prospective outcomes following drainless superficial parotidectomy with sternocleidomastoid flap reconstruction Open
Background Patients undergoing superficial parotidectomy for benign parotid lesions are at risk of postoperative complications, most notably cosmetic complications such as facial paralysis and contour defects, and functional complications …
View article: Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: A retrospective cohort study
Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: A retrospective cohort study Open
Background Distant metastasis in thyroid cancer significantly reduces survival in patients with well-differentiated thyroid carcinoma (WDTC). There is limited information available to clinicians regarding pathological features that confer …
View article: Composite submental flaps in facial reconstructive surgery involving the zygoma and orbit
Composite submental flaps in facial reconstructive surgery involving the zygoma and orbit Open
Background The submental island flap (SIF) is a reliable option for reconstructing defects in the facial region and offers several advantages when compared to free-flap alternatives. While the reconstructive applications of the SIF have be…
View article: Open resection and reconstruction of a Nasoseptal Chondrosarcoma: Case report and literature review
Open resection and reconstruction of a Nasoseptal Chondrosarcoma: Case report and literature review Open
Background Primary chondrosarcomas of the nasal septum are rare, with a variety of clinical features that evade detection and treatment. While endoscopic surgery has become increasingly accessible, open approaches may be needed to provide …
View article: Oncological and functional outcomes following transoral laser microsurgery in patients with T2a vs T2b glottic squamous cell carcinoma
Oncological and functional outcomes following transoral laser microsurgery in patients with T2a vs T2b glottic squamous cell carcinoma Open
Background There is a paucity of evidence comparing oncological and voice outcomes between T2a and T2b glottic squamous cell carcinoma (SCC) patients treated with transoral laser microsurgery (TLM). This study identified functional and onc…
View article: The role of repeat fine needle aspiration in managing indeterminate thyroid nodules
The role of repeat fine needle aspiration in managing indeterminate thyroid nodules Open
Background The Bethesda System is the most widely used for reporting fine needle aspiration (FNA) cytology. It recommends a repeat FNA (rFNA) when initial results are category I or III. It is unclear how often rFNA provides additional diag…
View article: Late Free Flap Failure in Head and Neck Reconstruction: A Systematic Review
Late Free Flap Failure in Head and Neck Reconstruction: A Systematic Review Open
Our objectives were to review all reported cases of late flap failure in head and neck surgery and describe any relevant patterns. We conducted a systematic review of all published cases of free flap failure after postoperative day 7 in he…
View article: Transoral Laser Surgery for Laryngeal Carcinoma: Has Steiner Achieved a Genuine Paradigm Shift in Oncological Surgery?
Transoral Laser Surgery for Laryngeal Carcinoma: Has Steiner Achieved a Genuine Paradigm Shift in Oncological Surgery? Open
Transoral laser microsurgery applies to the piecemeal removal of malignant tumours of the upper aerodigestive tract using the CO2 laser under the operating microscope. This method of surgery is being increasingly popularised as a single mo…
View article: The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of mouth
The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of mouth Open
View article: Report of metastatic ileal neuroendocrine tumor to the submandibular gland
Report of metastatic ileal neuroendocrine tumor to the submandibular gland Open