Explanipedia

Characterisation of the Novel HLA‐B*27:05:64 Allele by Sequencing‐Based Typing Open

Jonathan Visentin · 2025

HLA‐B*27:05:64 differs from HLA‐B*27:05:02:05 by one nucleotide substitution in codon −21 in exon 1.

Effector-Memory γδ T Lymphocytes Predict CMV Disease After the Withdrawal of Prophylaxis in Kidney Transplant Recipients Open

Yoann Abadie, Jonathan Visentin, Élodie Wojciechowski, Manon Charrier, Julie Déchanet‐Merville , et al. · 2025

Evaluation of CMV-specific cell-mediated immunity (CMI) has improved strategies to prevent post-transplant CMV disease. This study assessed the association between CMV disease and absolute count of TEMRA γδ T cells at the end of universal …

Characterisation of the HLA‐DPB1*104:01:08 Allele by Sequencing‐Based Typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Intissar Dalhoumi, Jonathan Visentin · 2025

HLA‐DPB1*104:01:08 differs from HLA‐DPB1*104:01:01:04 by one nucleotide substitution in codon 199 in exon 4.

Characterisation of the Novel HLA‐DQB1*05:357 Allele by Sequencing‐Based Typing Open

Vincent Elsermans, Jonathan Visentin, Thibault Pajot, Isabelle Top, Myriam Labalette · 2025

HLA‐DQB1*05:357 differs from HLA‐DQB1*05:03:01:01 by one nucleotide substitution in codon 6 in exon 2.

Characterisation of the Novel HLA‐DQA1*01:170 by Sequencing‐Based Typing Open

Marine Cargou, Marco Andreani, Antonio Giuseppe Bianculli, Mamy Ralazamahaleo, Jonathan Visentin · 2025

HLA‐DQA1*01:170 differs from HLA‐DQA1*01:03:01:02 by one nucleotide substitution in codon 183 in exon 4.

Characterisation of the Novel HLA ‐ DRB1 * 14 : 268 Allele by Sequencing‐Based Typing Open

Marine Cargou, Mamy Ralazamahaleo, Élodie Wojciechowski, Gwendaline Guidicelli, Jonathan Visentin · 2025

HLA‐DRB1*14:268 differs from HLA‐DRB1*14:54:01:03 by one nucleotide substitution in codon 213 in exon 4.

Characterisation of the Novel HLA‐DQA1*01:169 Allele by Sequencing‐Based Typing Open

Marine Cargou, Marco Andreani, Maria Troiano, Gwendaline Guidicelli, Jonathan Visentin · 2025

HLA‐DQA1*01:169 differs from HLA‐DQA1*01:01:01:09 by one nucleotide substitution in codon 175 in exon 3.

γδ T Cells’ Role in Donor-Specific Antibody Generation: Insights From Transplant Recipients and Experimental Models Open

Xavier Charmetant, Guillaume Rigault, Chien‐Chia Chen, Hannah Kaminski, Jonathan Visentin , et al. · 2025

The generation of donor-specific antibodies (DSA) requires that alloreactive B cells receive help from follicular helper T (T FH ) cells. Recent works have suggested that γδ T cells could contribute to T cell-dependent humoral responses, l…

Heightened TLR7 signaling primes BCR-activated B cells in chronic graft-versus-host disease for effector functions Open

Sonali J. Bracken, Amy N. Suthers, Rachel A. DiCioccio, Hsuan Su, Sarah Anand , et al. · 2023

Chronic graft-versus-host disease (cGVHD) is a debilitating, autoimmune-like syndrome that can occur after allogeneic hematopoietic stem cell transplantation. Constitutively activated B cells contribute to ongoing alloreactivity and autore…

Measurement of the Immunosuppressant Possession Ratio by Transplant Clinical Pharmacists Captures a Non-Adherence Associated With Antibody-Mediated Rejection Open

Jérémy Chambord, Bertrand Chauveau, Sarah Djabarouti, J Vignaud, Benjamin Taton , et al. · 2023

Our objective was to calculate an immunosuppressant possession ratio (IPR) to diagnose non-adherence at the time of antibody-mediated rejection (ABMR). IPR was defined as the ratio of number of pills collected at the pharmacy to the number…

Impact of Preformed Donor-Specific Anti-HLA-Cw and Anti-HLA-DP Antibodies on Acute Antibody-Mediated Rejection in Kidney Transplantation Open

Timothée Laboux, Rémi Lenain, Jonathan Visentin, Gauthier Flahaut, Paul Chamley , et al. · 2023

Given the risk of rejection, the presence of preformed donor specific antibodies (DSA) contraindicates transplantation in most allocation systems. However, HLA-Cw and -DP DSA escape this censorship. We performed a multicentric observationa…

Characterization of the novel HLA‐B*40:539 allele by sequencing‐based typing Open

Vincent Elsermans, Jonathan Visentin, Isabelle Top, Thibault Pajot, Myriam Labalette · 2023

HLA‐B*40:539 differs from HLA‐B*40:01:01 by one nucleotide substitution in codon 46 in exon 2.

25‐hydroxyvitamin D sufficiency is associated with lower de novo anti‐HLA donor specific antibody and better kidney transplant outcomes Open

Hugo Bakis, Charlène Bouthemy, Jean‐Benoît Corcuff, Cindy Lauro, Gwendaline Guidicelli , et al. · 2023

T‐cell mediated rejection (TCMR), de novo anti‐HLA donor‐specific antibodies ( dn DSAs) and ensuing antibody‐mediated rejection (ABMR) reduce kidney transplantation (KT) survival. The immunomodulatory effects of 25‐hydroxyvitamin D [25(OH)…

Characterization of the novel HLA‐DPA1*01:159 allele by sequencing‐based typing Open

Marine Cargou, Marco Andreani, Tiziana Galluccio, Élodie Wojciechowski, Jonathan Visentin · 2023

HLA‐DPA1*01:159 differs from HLA‐DPA1*01:03:01:03 by one nucleotide substitution in codon 120 in exon 3.

Characterization of the novel HLA‐DRB1*11:01:01:12N allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Charlotte A. Cambridge, Eulalie Lasseaux, Jonathan Visentin · 2023

HLA‐DRB1*11:01:01:12N differs from HLA‐DRB1*11:01:01:03 by one nucleotide substitution in intron 3 at position c.652+1G>C, hg19.

Characterization of the novel HLA‐DPA1*01:150 allele by sequencing‐based typing Open

Marine Cargou, Marco Andreani, Paola Giustiniani, Marion Duclaut, Jonathan Visentin · 2023

HLA‐DPA1*01:150 differs from HLA‐DPA1*01:03:01:05 by one nucleotide substitution in codon 190 in exon 4.

Characterization of the novel HLA‐C*12:384 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Élodie Wojciechowski, Jonathan Visentin · 2023

HLA‐C*12:384 differs from HLA‐C*12:03:01:02 by one nucleotide substitution in codon 42 in exon 2.

Characterization of the novel HLA‐DPB1*1463:01N allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Mamy Ralazamahaleo, Jonathan Visentin · 2023

HLA‐DPB1*1463:01N differs from HLA‐DPB1*02:01:02:04 by one nucleotide substitution in codon 128 in exon 3.

Characterization of the novel HLA‐B*44:324:02 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Gwendaline Guidicelli, Jonathan Visentin · 2023

HLA‐B*44:324:02 differs from HLA‐B*44:324:01 by one nucleotide substitution in codon 99 in exon 3.

Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD Open

Jonathan C. Poe, Jiyuan Fang, Dadong Zhang, Marissa R. Lee, Rachel A. DiCioccio , et al. · 2023

Alloreactivity can drive autoimmune syndromes. After allogeneic hematopoietic stem cell transplantation (allo-HCT), chronic graft-versus-host disease (cGVHD), a B cell-associated autoimmune-like syndrome, commonly occurs. Because donor-der…

Characterization of the novel HLA‐A*24:587 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Élodie Wojciechowski, Jonathan Visentin · 2023

HLA‐A*24:587 differs from HLA‐A*24:02:01:01 by one nucleotide substitution in codon 220 in exon 4.

Characterization of the novel HLA‐C*05:01:01:81Q allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Virginie Raclet, Élodie Wojciechowski, Jonathan Visentin · 2023

HLA‐C*05:01:01:81Q differs from HLA‐C*05:01:01:02 by one nucleotide substitution in position 202 in intron 1 (c.74‐2A>G, hg19).

Characterization of the novel HLA‐A*24:585 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Élodie Wojciechowski, Jonathan Visentin · 2023

HLA‐A*24:585 differs from HLA‐A*24:02:01:01 by one nucleotide substitution in codon ‐15 in exon 1.

Characterization of the novel HLA‐DRB1*01:140 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Gwendaline Guidicelli, Jonathan Visentin · 2023

HLA‐DRB1*01:140 differs from HLA‐DRB1*01:02:01:01 by one nucleotide substitution in codon 147 in exon 3.

Characterization of the novel HLA‐B*51:370 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Mamy Ralazamahaleo, Jonathan Visentin · 2023

HLA‐B*51:370 differs from HLA‐B*51:01:01:04 by one nucleotide substitution in codon 276 in exon 5.

Cytomegalovirus DNAemia Requiring (Val)Ganciclovir Treatment for More Than 8 Weeks Is a Key Factor in the Development of Antiviral Drug Resistance Open

Mathieu Acquier, Benjamin Taton, Sophie Alain, Isabelle Garrigue, Julien Mary , et al. · 2023

Background Prolonged (val)ganciclovir [(V)GCV] exposure for ≥6 weeks is a known predisposing factor for cytomegalovirus (CMV) drug resistance. However, the selection of this threshold was based on limited data. In this study, we sought to …

Characterization of the novel HLA‐DQA1*05:05:14 allele by sequencing‐based typing Open

Marine Cargou, Marco Andreani, Mariarosa Battarra, Mamy Ralazamahaleo, Jonathan Visentin · 2022

HLA ‐ DQA1 * 05 : 05 : 14 differs from HLA ‐ DQA1 * 05 : 05 : 01 : 04 by one nucleotide substitution in codon −8 in exon 1.

Characterization of the novel HLA‐DPB1*11:01:06 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Élodie Wojciechowski, Jonathan Visentin · 2022

HLA‐DPB1 * 11:01:06 differs from HLA‐DPB1 * 11:01:01:01 by one nucleotide substitution in codon 21 in exon 2.

Characterization of the novel HLA‐B*08:302 allele by sequencing‐based typing Open

Marine Cargou, Vincent Elsermans, Isabelle Top, Élodie Wojciechowski, Jonathan Visentin · 2022

HLA‐B * 08:302 differs from HLA‐B * 08:01:01:01 by one nucleotide substitution in codon 116 in exon 3.

Characterization of the novel HLA‐DQA1*02:01:14 allele by sequencing‐based typing Open

Marine Cargou, Marco Andreani, Maria Troiano, Gwendaline Guidicelli, Jonathan Visentin · 2022

HLA‐DQA1*02:01:14 differs from HLA‐DQA1*02:01:01:02 by one nucleotide substitution in codon 105 in exon 3.

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