Jonathan Wyllie
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View article: Surgery versus conservative management for severe pectus excavatum (RESTORE): protocol for a multicentre, randomised, controlled superiority trial
Surgery versus conservative management for severe pectus excavatum (RESTORE): protocol for a multicentre, randomised, controlled superiority trial Open
Introduction Severe pectus excavatum (PE) may impair cardiopulmonary and physical function. The effectiveness of surgical treatment to correct PE and restore physical function is widely debated due to a lack of high-quality comparative evi…
View article: Two-year outcomes after selective early treatment of patent ductus arteriosus with ibuprofen in preterm babies: follow-up of Baby-OSCAR–a randomised controlled trial
Two-year outcomes after selective early treatment of patent ductus arteriosus with ibuprofen in preterm babies: follow-up of Baby-OSCAR–a randomised controlled trial Open
This study was funded by the National Institute for Health Research (NIHR) Health Technology Assessment Programme (11/92/15).
View article: Economic Evaluation alongside the Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen in Extreme Preterm Babies
Economic Evaluation alongside the Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen in Extreme Preterm Babies Open
Objective To conduct an economic evaluation alongside the placebo-controlled trial of selective early treatment of patent ductus arteriosus with ibuprofen in extreme preterm babies. Design Within-trial economic evaluation alongside a multi…
View article: Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen
Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen Open
The risk of death or moderate or severe bronchopulmonary dysplasia at 36 weeks of postmenstrual age was not significantly lower among infants who received early treatment with ibuprofen than among those who received placebo. (Funded by the…
View article: 545 Does selective early treatment of Patent Ductus Arteriosus (PDA) with ibuprofen reduce death or Bronchopulmonary Dysplasia (BPD) at 36 weeks in extreme preterm babies? A Randomised Controlled Trial (Baby-OSCAR Trial)
545 Does selective early treatment of Patent Ductus Arteriosus (PDA) with ibuprofen reduce death or Bronchopulmonary Dysplasia (BPD) at 36 weeks in extreme preterm babies? A Randomised Controlled Trial (Baby-OSCAR Trial) Open
Aims The management of PDA continues to be a clinical conundrum in extremely low gestational age newborns (ELGANS). Presence of a PDA at 72 hours after birth in ELGANS is associated with an increased risk of death and complications of prem…
View article: Sustained Lung Inflations During Neonatal Resuscitation at Birth: A Meta-analysis
Sustained Lung Inflations During Neonatal Resuscitation at Birth: A Meta-analysis Open
CONTEXT: The International Liaison Committee on Resuscitation prioritized review of sustained inflation (SI) of the lung at birth. OBJECTIVE: To complete a systematic review and meta-analysis comparing strategies using 1 or more SI ≥1 seco…
View article: Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Open
This 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations (CoSTR) for neonatal life support includes evidence from 7 systematic reviews, 3 scoping reviews, a…
View article: 2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces
2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces Open
The International Liaison Committee on Resuscitation has initiated a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation science. This is the third annual summary of the International Liaison Committee on Resus…