Jonathan Y. Ting
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View article: CNSC-22. GLIOBLASTOMA CELLS EXHIBIT NEURON-LIKE EXCITABILITY IN BOTH ACUTE AND ORGANOTYPIC HUMAN BRAIN SLICES
CNSC-22. GLIOBLASTOMA CELLS EXHIBIT NEURON-LIKE EXCITABILITY IN BOTH ACUTE AND ORGANOTYPIC HUMAN BRAIN SLICES Open
Glioblastomas (GBM) are known for their significant intratumor heterogeneity, featuring a variety of plastic cell types that make effective treatment challenging. Recent studies have shown that neuronal-progenitor-like transcriptomic cell …
View article: Development of the 12-Item Facial Complaints Evaluation Scale (FaCES-12)
Development of the 12-Item Facial Complaints Evaluation Scale (FaCES-12) Open
Objectives: Chronic rhinosinusitis and related rhinologic disorders are common in routine otolaryngologic practice. Common presenting symptoms include nasal obstruction, facial pain, facial pressure, headache, and a subjective feeling of t…
View article: Author Correction: Conserved and divergent gene regulatory programs of the mammalian neocortex
Author Correction: Conserved and divergent gene regulatory programs of the mammalian neocortex Open
In the version of the article initially published, in Figs.2c andd and5e, numbers in labels had been rounded.These have been corrected to exact numbers.In Fig. 2c andd, the labels now read "Mammal level 3 (16,068)", "Human biased ↑ (10,743…
View article: Frontal Sinus Anatomy Variations in Race and Sex Using the International Frontal Sinus Anatomy Classification
Frontal Sinus Anatomy Variations in Race and Sex Using the International Frontal Sinus Anatomy Classification Open
Objective: To identify frontal sinus anatomical variations grouped by patient sex, race, and presence of chronic rhinosinusitis with frontal sinus involvement (CRFS) using the International Frontal Sinus Anatomy Classification (IFAC) syste…
View article: Comparative single cell epigenomic analysis of gene regulatory programs in the rodent and primate neocortex
Comparative single cell epigenomic analysis of gene regulatory programs in the rodent and primate neocortex Open
Sequence divergence of cis- regulatory elements drives species-specific traits, but how this manifests in the evolution of the neocortex at the molecular and cellular level remains to be elucidated. We investigated the gene regulatory prog…
View article: Postoperative Polyp Scale (<scp>POPS</scp>): Development of a New Sinonasal Polyp Grading Scale
Postoperative Polyp Scale (<span>POPS</span>): Development of a New Sinonasal Polyp Grading Scale Open
Objective Commonly used endoscopic grading scales, such as the nasal polyp scale, inadequately describe the degree of polyposis found postoperatively in the paranasal sinus cavities. The purpose of this study was to create a novel grading …
View article: Surgical Repair of Septal Perforations: Comparison of Pedicled Anterior Ethmoid Flap vs. Temporalis Fascia Graft Techniques
Surgical Repair of Septal Perforations: Comparison of Pedicled Anterior Ethmoid Flap vs. Temporalis Fascia Graft Techniques Open
Background: Nasal septal perforations (NSP) cause a variety of bothersome symptoms for patients, and when medical management fails, surgical repair is indicated. Objective: This study examines the efficacy of a NSP repair method utilizing …
View article: A Sparse Sampling Sensor Front-end IC for Low Power Continuous SpO$_2$ \& HR Monitoring
A Sparse Sampling Sensor Front-end IC for Low Power Continuous SpO$_2$ \& HR Monitoring Open
Photoplethysmography (PPG) is an attractive method to acquire vital signs such as heart rate and blood oxygenation and is frequently used in clinical and at-home settings. Continuous operation of health monitoring devices demands a low pow…
View article: Simulation of laryngotracheal reconstruction with <scp>3D</scp>‐printed models and porcine cadaveric models
Simulation of laryngotracheal reconstruction with <span>3D</span>‐printed models and porcine cadaveric models Open
Objectives Laryngotracheal reconstruction (LTR) is a complex operation used to treat subglottic stenosis. The use of simulator models is a valuable tool in surgical trainee education, particularly for operations such as LTR that are less c…
View article: Telemedicine in Otolaryngology During COVID-19: An Exploratory Assessment of Provider and Patient Attitudes
Telemedicine in Otolaryngology During COVID-19: An Exploratory Assessment of Provider and Patient Attitudes Open
Objective: To determine provider and patient attitudes toward telemedicine in Otolaryngology—Head and Neck Surgery (OHNS). Methods: Otolaryngology practitioners conducting outpatient clinics at an academic tertiary referral center were pro…
View article: Orbital Complications of Acute Sinusitis in Pediatric Patients: Management of Chandler III Patients
Orbital Complications of Acute Sinusitis in Pediatric Patients: Management of Chandler III Patients Open
Background Surgery is often avoided in the setting of pediatric orbital complications from acute sinusitis unless necessitated by alarming ophthalmological signs. Criteria for surgical intervention are not well-defined. Objective We aim to…
View article: COVID-19 Vaccine Safety in Cancer Patients: A Single Centre Experience
COVID-19 Vaccine Safety in Cancer Patients: A Single Centre Experience Open
Emergency approval of vaccines against COVID-19 provides an opportunity for us to return to pre-pandemic oncology care. However, safety data in cancer patients is lacking due to their exclusion from most phase III trials. We included all p…
View article: Overcoming Operator-Generated False-Negative Results in SARS-CoV-2 Testing—Reply
Overcoming Operator-Generated False-Negative Results in SARS-CoV-2 Testing—Reply Open
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization…
View article: Aerosol generation during routine rhinologic surgeries and <scp>in‐office</scp> procedures
Aerosol generation during routine rhinologic surgeries and <span>in‐office</span> procedures Open
Objective Cadaveric simulations have shown endonasal drilling and cautery generate aerosols, which is a significant concern for otolaryngologists during the COVID‐19 era. This study quantifies aerosol generation during routine rhinologic s…
View article: YouTube Videos Demonstrating the Nasopharyngeal Swab Technique for SARS-CoV-2 Specimen Collection: Content Analysis
YouTube Videos Demonstrating the Nasopharyngeal Swab Technique for SARS-CoV-2 Specimen Collection: Content Analysis Open
Background Real-time polymerase chain reaction using nasopharyngeal swabs is currently the most widely used diagnostic test for SARS-CoV-2 detection. However, false negatives and the sensitivity of this mode of testing have posed challenge…
View article: Diagnosis of Anosmia and Hyposmia: A Systematic Review
Diagnosis of Anosmia and Hyposmia: A Systematic Review Open
Background Anosmia and hyposmia have many etiologies, including trauma, chronic sinusitis, neoplasms, and respiratory viral infections such as rhinovirus and SARS-CoV-2. We aimed to systematically review the literature on the diagnostic ev…
View article: Aerosol generation during cadaveric simulation of otologic surgery and live cochlear implantation
Aerosol generation during cadaveric simulation of otologic surgery and live cochlear implantation Open
Objective The risk of SARS‐CoV‐2 transmission to healthcare workers through airborne aerosolization during otologic surgery has not been characterized. The objective of this study was to describe and quantify the aerosol generation during …
View article: Comparison of Patient Satisfaction Between Virtual Visits During the COVID-19 Pandemic and In-person Visits Pre-pandemic
Comparison of Patient Satisfaction Between Virtual Visits During the COVID-19 Pandemic and In-person Visits Pre-pandemic Open
Objective: To compare the patient experience of a virtual otolaryngology clinic visit to an in-person visit, especially with its significantly increased implementation during the COVID-19 pandemic. Methods: Patient satisfaction (PS) metric…
View article: Use of Google Trends to investigate anosmia: power and pitfalls of infodemiology
Use of Google Trends to investigate anosmia: power and pitfalls of infodemiology Open
To the Editor: We read the recent study by Walker et al.1 with great interest. The authors describe using Google Trends (GT) relative search volume (RSV) data to correlate increases in online searches for smell loss to coronavirus disease …
View article: COVID‐19 Status Differentially Affects Olfaction: A Prospective Case‐Control Study
COVID‐19 Status Differentially Affects Olfaction: A Prospective Case‐Control Study Open
Objective The symptoms and long‐term sequelae of SARS‐CoV‐2 infection have yet to be determined, and evaluating possible early signs is critical to determine which patients should be tested and treated. The objective of this ongoing study …
View article: The association of weather, temperature, and holidays on pediatric maxillofacial trauma
The association of weather, temperature, and holidays on pediatric maxillofacial trauma Open
Objective To evaluate the association of weather, seasons, months and holidays on the frequency and pattern of pediatric facial fractures. Methods Retrospective review of pediatric patients treated for facial fractures at two Level I traum…
View article: SARS-CoV-2 Nasopharyngeal Swab Testing—False-Negative Results From a Pervasive Anatomical Misconception
SARS-CoV-2 Nasopharyngeal Swab Testing—False-Negative Results From a Pervasive Anatomical Misconception Open
This article is made available for unrestricted research re-use and secondary analysis in any form or be any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization…
View article: YouTube Videos Demonstrating the Nasopharyngeal Swab Technique for SARS-CoV-2 Specimen Collection: Content Analysis (Preprint)
YouTube Videos Demonstrating the Nasopharyngeal Swab Technique for SARS-CoV-2 Specimen Collection: Content Analysis (Preprint) Open
BACKGROUND Real-time polymerase chain reaction using nasopharyngeal swabs is currently the most widely used diagnostic test for SARS-CoV-2 detection. However, false negatives and the sensitivity of this mode of testing have posed challeng…
View article: Droplet Exposure Risk to Providers From In‐Office Flexible Laryngoscopy: A COVID‐19 Simulation
Droplet Exposure Risk to Providers From In‐Office Flexible Laryngoscopy: A COVID‐19 Simulation Open
To provide data on risk of respiratory droplets from common otolaryngologic procedures during the COVID‐19 pandemic, a novel simulation of droplet exposure from flexible laryngoscopy was performed. After completion of a nasal symptom quest…
View article: Mitigation of Aerosols Generated During Rhinologic Surgery: A Pandemic‐Era Cadaveric Simulation
Mitigation of Aerosols Generated During Rhinologic Surgery: A Pandemic‐Era Cadaveric Simulation Open
Objective After significant restrictions initially due to the COVID‐19 pandemic, otolaryngologists have begun resuming normal clinical practice. However, the risk of SARS‐CoV‐2 transmission to health care workers through aerosolization and…