Jong Won Yun
YOU?
Author Swipe
View article: A 3D <i>in vitro</i> model of the human hepatobiliary junction
A 3D <i>in vitro</i> model of the human hepatobiliary junction Open
Cholestasis, or disruption in bile flow, is a common yet poorly understood feature of many liver diseases and injuries. Despite this, many engineered human tissue models of liver disease fail to recapitulate physiological bile flow. Here, …
View article: Pan-Asia adapted ESMO Clinical Practice Guideline for the management of patients with newly diagnosed and relapsed epithelial ovarian cancer
Pan-Asia adapted ESMO Clinical Practice Guideline for the management of patients with newly diagnosed and relapsed epithelial ovarian cancer Open
The European Society for Medical Oncology (ESMO) Clinical Practice Guideline for the diagnosis, treatment and follow-up of patients with newly diagnosed and relapsed epithelial ovarian cancer (EOC), published in 2023, was adapted in July 2…
View article: Echinacoside Induces UCP1- and ATP-Dependent Thermogenesis in Beige Adipocytes <i>via</i> the Activation of Dopaminergic Receptors
Echinacoside Induces UCP1- and ATP-Dependent Thermogenesis in Beige Adipocytes <i>via</i> the Activation of Dopaminergic Receptors Open
Echinacoside (ECH) is a naturally occurring phenylethanoid glycoside, isolated from Echinacea angustifolia, and this study aimed to analyze its effect on thermogenesis and its interaction with dopaminergic receptors 1 and 5 (DRD1 and DRD5)…
View article: Supplementary Tables 1 - 6 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
Supplementary Tables 1 - 6 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model Open
PDF file - 167K, Supplemental Table 1. Effect of licochalcone E (LicE) on body weights and organ weights in BALB/c mice injected with 4T1 cells. Supplemental Table 2. Effect of licochalcone E (LicE) on the levels of creatinine and the acti…
View article: Data from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
Data from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model Open
We investigated whether licochalcone E (LicE), a phenolic constituent of licorice, inhibits mammary tumor growth and metastasis using animal and cell culture models. 4T1 mammary carcinoma cells were injected into the mammary fat pads of sy…
View article: Supplementary Tables 1 - 6 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
Supplementary Tables 1 - 6 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model Open
PDF file - 167K, Supplemental Table 1. Effect of licochalcone E (LicE) on body weights and organ weights in BALB/c mice injected with 4T1 cells. Supplemental Table 2. Effect of licochalcone E (LicE) on the levels of creatinine and the acti…
View article: Supplementary Figures 1 - 3 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
Supplementary Figures 1 - 3 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model Open
PDF file - 303K, Supplemental Figure 1. Chemical structure of licochalcone E (LicE). Supplemental Figure 2. Licochalcone E decreases the tube formation of endothelial cells. Supplemental Figure 3. Licochalcone E decreases the secretion of …
View article: Supplementary Figures 1 - 3 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
Supplementary Figures 1 - 3 from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model Open
PDF file - 303K, Supplemental Figure 1. Chemical structure of licochalcone E (LicE). Supplemental Figure 2. Licochalcone E decreases the tube formation of endothelial cells. Supplemental Figure 3. Licochalcone E decreases the secretion of …
View article: Data from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
Data from Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model Open
We investigated whether licochalcone E (LicE), a phenolic constituent of licorice, inhibits mammary tumor growth and metastasis using animal and cell culture models. 4T1 mammary carcinoma cells were injected into the mammary fat pads of sy…
View article: Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity
Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity Open
Type 2 diabetes is a metabolic disease with a group of metabolic derangements and inflammatory reactants in the serum. Despite the substantial public health implications, markers of diabetes progression with abdominal obesity are still nee…
View article: Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes
Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes Open
Recently, pharmacological activation of brown fat and induction of white fat browning (beiging) have been considered promising strategies to treat obesity. To search for natural products that could stimulate the process of browning in adip…
View article: Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells
Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells Open
Heat shock transcription factor-1 (HSF-1) guards the cancerous cells proteome against the alterations in protein homeostasis generated by their hostile tumor microenvironment. Contrasting with the classical induction of heat shock proteins…
View article: Quercetin Protects Obesity-Induced Hypothalamic Inflammation by Reducing Microglia-Mediated Inflammatory Responses via HO-1 Induction
Quercetin Protects Obesity-Induced Hypothalamic Inflammation by Reducing Microglia-Mediated Inflammatory Responses via HO-1 Induction Open
Obesity-induced hypothalamic inflammation is characterized by activation of microglia, which are resident macrophages of the central nervous system, and is implicated in the derangement of energy homeostasis, metabolic complications, and n…
View article: Combined inhibition of autophagy protein 5 and galectin‐1 by thiodigalactoside reduces diet‐induced obesity through induction of white fat browning
Combined inhibition of autophagy protein 5 and galectin‐1 by thiodigalactoside reduces diet‐induced obesity through induction of white fat browning Open
Our previous study demonstrated that thiodigalactoside (TDG) ameliorates obesity by targeted inhibition of galectin‐1 (GAL1). Here, for the first time, we report the unexpected role of GAL1 and ATG5 inhibition by TDG in lipid metabolism. C…