Jongki Cho
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View article: Targeted knock-in of human immune-regulatory genes into the porcine GGTA1 exon 4 reveals divergent expression on red blood cell membranes
Targeted knock-in of human immune-regulatory genes into the porcine GGTA1 exon 4 reveals divergent expression on red blood cell membranes Open
The decline in blood donations has become a global challenge, emphasizing the urgent need for alternatives to meet the growing demand. One potential solution is the development of transgenic pigs whose blood can overcome immune rejection a…
View article: Evaluation of the functional role of corpus luteum cavity in recipient selection for bovine embryo transfer
Evaluation of the functional role of corpus luteum cavity in recipient selection for bovine embryo transfer Open
These findings suggest that CLcav does not impair luteal function or pregnancy outcomes and may, in some cases, indicate enhanced luteal activity. Integrating CL morphology, vascularization, and hormonal balance into recipient selection cr…
View article: Targeted knock-in of human immune-regulatory genes into the porcine GGTA1 exon 4 reveals divergent expression on red blood cell membranes
Targeted knock-in of human immune-regulatory genes into the porcine GGTA1 exon 4 reveals divergent expression on red blood cell membranes Open
The decline in blood donations has become a global challenge, emphasizing the urgent need for alternatives to meet the growing demand. One potential solution is the development of transgenic pigs whose blood can overcome immune rejection a…
View article: Xanthogranulomatous metritis in a Korean short-haired cat: a case report
Xanthogranulomatous metritis in a Korean short-haired cat: a case report Open
A case of xanthogranulomatous metritis in a 5-year-old Korean short-haired cat is presented. Yellowish-white nodules, 1 to 2 cm in diameter and protruding from the perimetrium, were detected. Histopathological examination revealed extensiv…
View article: Metabolite Profiling and Antimicrobial Activities of Brassica rapa ssp. narinosa (Tatsoi), Brassica rapa var. narinosa × chinensis (Dacheongchae), and Brassica rapa ssp. chinensis (Pakchoi)
Metabolite Profiling and Antimicrobial Activities of Brassica rapa ssp. narinosa (Tatsoi), Brassica rapa var. narinosa × chinensis (Dacheongchae), and Brassica rapa ssp. chinensis (Pakchoi) Open
Pakchoi and Tatsoi are agriculturally and commercially important subspecies of Brassica rapa. Dacheongchae is a new crop generated via the hybridization of Tatsoi and Pakchoi. Metabolite profiles of carbohydrates, sugar alcohols, amines, a…
View article: Effects of steroid hormone-treated endometrial organoids on the implantation of <i>in vitro</i>-produced porcine embryos
Effects of steroid hormone-treated endometrial organoids on the implantation of <i>in vitro</i>-produced porcine embryos Open
This study confirmed that porcine endometrial organoids respond to steroid hormones and support embryo attachment. These findings provide a translational basis for developing in vitro models to study implantation failure and infertility in…
View article: Successful pregnancy in estrus-synchronized Himalayan tahrs ( <i>Hemitragus jemlahicus</i> ) by transcervical insemination
Successful pregnancy in estrus-synchronized Himalayan tahrs ( <i>Hemitragus jemlahicus</i> ) by transcervical insemination Open
Thirteen-day CIDR insertion combined with gonadotropins and PGF2α is effective for estrus synchronization in Himalayan tahrs. Transcervical insemination using EF and EC semen resulted in successful pregnancy, offering a practical and repro…
View article: Effects of extracellular vesicles (EVs) from uterine fluid during estrus and diestrus on porcine embryonic development
Effects of extracellular vesicles (EVs) from uterine fluid during estrus and diestrus on porcine embryonic development Open
Background: Porcine embryonic development is widely utilized in the medical industry. However, the blastocyst development rate in vitro is lower compared to in vivo. To address this issue, various supplements are employed. Extracellular ve…
View article: The reprotoxic adverse side effects of neurogenic and neuroprotective drugs: current use of human organoid modeling as a potential alternative to preclinical models
The reprotoxic adverse side effects of neurogenic and neuroprotective drugs: current use of human organoid modeling as a potential alternative to preclinical models Open
The management of neurological disorders heavily relies on neurotherapeutic drugs, but notable concerns exist regarding their possible negative effects on reproductive health. Traditional preclinical models often fail to accurately predict…
View article: Melatonin and resveratrol alleviate molecular and metabolic toxicity induced by Bisphenol A in endometrial organoids
Melatonin and resveratrol alleviate molecular and metabolic toxicity induced by Bisphenol A in endometrial organoids Open
Bisphenol A (BPA), a widespread environmental contaminant, poses concerns due to its disruptive effects on physiological functions of the uterine endometrium. In contrast, melatonin (MT) and Resveratrol (RSV) are under scrutiny for their p…
View article: Exploring the Production of Secondary Metabolites from a Halophyte Tetragonia tetragonoides through Callus Culture
Exploring the Production of Secondary Metabolites from a Halophyte Tetragonia tetragonoides through Callus Culture Open
Considering Korea’s gradual shift toward an aging society, consumer interest in compounds with physiological benefits, including antioxidant and anticancer effects, has surged. This study explored the potential of Tetragonia tetragonoides …
View article: Current strategies using 3D organoids to establish <i>in vitro</i> maternal-embryonic interaction
Current strategies using 3D organoids to establish <i>in vitro</i> maternal-embryonic interaction Open
This review provides insights into the future direction of modeling maternal-embryonic interaction research and its combination with other powerful technologies to interfere with this dialogue either by promoting or hindering it for improv…
View article: Effects of follicular fluid-derived extracellular vesicles improve in vitro maturation and embryonic development of porcine oocytes
Effects of follicular fluid-derived extracellular vesicles improve in vitro maturation and embryonic development of porcine oocytes Open
To optimize the most efficient method for porcine in vitro maturation (IVM), we compared the effects of supplementing extracellular vesicles (EVs) derived from porcine follicular fluid (pFF). The cumulus oocyte complexes were grouped into …
View article: Leaf Area Prediction of Pennywort Plants Grown in a Plant Factory Using Image Processing and an Artificial Neural Network
Leaf Area Prediction of Pennywort Plants Grown in a Plant Factory Using Image Processing and an Artificial Neural Network Open
The leaf is a primary part of a plant, and examining the leaf area is crucial in understanding growth and plant physiology. Accurately estimating leaf area is key to this understanding. This study proposed a methodology for the non-destruc…
View article: Sex ratio and conception rates of fresh/vitrified embryos at different developmental stages by ovum pick up in Hanwoo cows
Sex ratio and conception rates of fresh/vitrified embryos at different developmental stages by ovum pick up in Hanwoo cows Open
Embryo transfer plays a crucial role in enhancing the breeding value of livestock; it has been applied in Hanwoo cattle, which is a popular breed for beef production in Korea. Both in vivo-derived (IVD) and in vitro-produced (IVP) embryos …
View article: Retraction notice to “Centella asiatica extract in Carboxymethyl Cellulose at its optimal concentration improved wound healing in mice model” [Heliyon 8, (2022) Article e12031]
Retraction notice to “Centella asiatica extract in Carboxymethyl Cellulose at its optimal concentration improved wound healing in mice model” [Heliyon 8, (2022) Article e12031] Open
[This retracts the article DOI: 10.1016/j.heliyon.2022.e12031.].
View article: Improved pregnancy rate and sex ratio in fresh/frozen in vivo derived embryo transfer of Hanwoo (Bos taurus coreanae) cows
Improved pregnancy rate and sex ratio in fresh/frozen in vivo derived embryo transfer of Hanwoo (Bos taurus coreanae) cows Open
This study aimed to assess the effects of embryonic developmental stage, quality grade, and fresh or frozen/thawed conditions on the pregnancy rate and sex ratio of live offspring in Hanwoo (Bos taurus coreanae) cows. The quality and devel…
View article: Oviduct epithelial cell‑derived extracellular vesicles promote the developmental competence of IVF porcine embryos
Oviduct epithelial cell‑derived extracellular vesicles promote the developmental competence of IVF porcine embryos Open
Assisted reproductive technology has increased the efficiency of animal reproduction. However, polyspermy is a significant limitation of porcine in vitro fertilization (IVF). Therefore, reducing the polyspermy rate and improving monospermi…
View article: Isolation, characterization, proteome, miRNAome, and the embryotrophic effects of chicken egg yolk nanovesicles (vitellovesicles)
Isolation, characterization, proteome, miRNAome, and the embryotrophic effects of chicken egg yolk nanovesicles (vitellovesicles) Open
Egg yolk constitutes about a third of the structure of the chicken egg however, the molecular structure and physiological effects of egg yolk-derived lipid membranous vesicles are not clearly understood. In this study, for the first record…
View article: RETRACTED: Centella asiatica extract in carboxymethyl cellulose at its optimal concentration improved wound healing in mice models
RETRACTED: Centella asiatica extract in carboxymethyl cellulose at its optimal concentration improved wound healing in mice models Open
Centella asiatica (C. asiatica) has reported to be one of the traditional herbal remedies, whereas poor water solubility leads to lower bioavailability thereby affecting it remedial efficacy. Therefore, we aimed to evaluate its efficacy th…
View article: Role of antioxidants in fertility preservation of sperm — A narrative review
Role of antioxidants in fertility preservation of sperm — A narrative review Open
Male fertility is affected by multiple endogenous stressors, including reactive oxygen species (ROS), which greatly deteriorate the fertility. However, physiological levels of ROS are required by sperm for the proper accomplishment of diff…
View article: Oviduct Epithelial Cell-Derived Extracellular Vesicles Improve Porcine Trophoblast Outgrowth
Oviduct Epithelial Cell-Derived Extracellular Vesicles Improve Porcine Trophoblast Outgrowth Open
Porcine species have a great impact on studies on biomaterial production, organ transplantation and the development of biomedical models. The low efficiency of in vitro-produced embryos to derive embryonic stem cells has made achieving thi…
View article: ROCK Inhibitor (Y-27632) Abolishes the Negative Impacts of miR-155 in the Endometrium-Derived Extracellular Vesicles and Supports Embryo Attachment
ROCK Inhibitor (Y-27632) Abolishes the Negative Impacts of miR-155 in the Endometrium-Derived Extracellular Vesicles and Supports Embryo Attachment Open
Extracellular vesicles (EVs) are nanosized vesicles that act as snapshots of cellular components and mediate cellular communications, but they may contain cargo contents with undesired effects. We developed a model to improve the effects o…