Jong‐Seo Yoon
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View article: Signature Gene Mutations in Colorectal Cancer: Potential Neoantigens for Cancer Vaccines
Signature Gene Mutations in Colorectal Cancer: Potential Neoantigens for Cancer Vaccines Open
Colorectal cancer (CRC), the third most common cancer worldwide, is one of the deadliest cancers. CRC is known as a cold tumor, characterized by a low immune response that makes it difficult for immune cells to infiltrate and exhibits stro…
View article: Metabolic click-labeling of interleukin-10 enhances the immunomodulatory potential and wound healing properties of mesenchymal stem cell-derived extracellular nanovesicles
Metabolic click-labeling of interleukin-10 enhances the immunomodulatory potential and wound healing properties of mesenchymal stem cell-derived extracellular nanovesicles Open
Integration of interleukin-10 to mesenchymal stem cell-derived extracellular nanovesicles effectively enhances anti-inflammatory responses in both macrophages and DCs, ultimately accelerating the skin wound healing in vivo.
View article: Impulse oscillometry system for assessing small airway dysfunction in pediatric bronchiolitis obliterans; association with conventional pulmonary function tests
Impulse oscillometry system for assessing small airway dysfunction in pediatric bronchiolitis obliterans; association with conventional pulmonary function tests Open
Impulse oscillometry system (IOS) is a simple, and less invasive method for assessing small to total airway resistance in children. We analyzed the correlation between IOS, spirometry, and plethysmographic parameters performed for the diag…
View article: One‐year changes in the pediatric emergency department caused by prolonged coronavirus disease 2019 pandemic
One‐year changes in the pediatric emergency department caused by prolonged coronavirus disease 2019 pandemic Open
Background With the coronavirus disease 2019 (COVID‐19) pandemic lasting for more than a year, it is imperative to identify the associated changes in the use of emergency medical care for efficient operation of the pediatric emergency depa…
View article: Relationship between impulse oscillometry system and conventional lung function test for diagnosis of bronchiolitis obliterans in children
Relationship between impulse oscillometry system and conventional lung function test for diagnosis of bronchiolitis obliterans in children Open
Background: Functional assessment of small airways in young children with bronchiolitis obliterans (BO) is challenging due to their relative inaccessibility and the generally poor lung function test performance of these patients. We analyz…
View article: Mortality of Children Treated in A Pediatric Intensive Care Unit Versus Other Intensive Care Units
Mortality of Children Treated in A Pediatric Intensive Care Unit Versus Other Intensive Care Units Open
Background: Korean children are often treated in Intensive Care Units (ICUs) rather than in Pediatric Intensive Care Units (PICUs). However, pediatric critical care (PCC) in ICUs, other than in PICUs, may have effects on patient's outcome.…
View article: The diagnostic usefulness and correlation of nasal eosinophil count and percentage in children with rhinitis
The diagnostic usefulness and correlation of nasal eosinophil count and percentage in children with rhinitis Open
Purpose: Allergic rhinitis is the most common atopic disease and the most common chronic disease of children. Eosinophil count and percentage in nasal smear are useful for differential diagnosis of allergic rhinitis. The aim of this study …
View article: Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis
Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis Open
Nasal eosinophil count was significantly associated with protein-corrected EPO.
View article: Tracheostomy in children: A 9-year experience in a tertiary hospital in Korea
Tracheostomy in children: A 9-year experience in a tertiary hospital in Korea Open
Purpose: Tracheostomy has been increasingly performed in children, along with the improvements in neonatal and pediatric intensive care. The objective of this study was to describe the indications, comorbidities, complications, and outcome…
View article: Foreign body removal by flexible bronchoscopy using retrieval basket in children
Foreign body removal by flexible bronchoscopy using retrieval basket in children Open
OBJECTIVES: Aspiration of foreign bodies into the tracheobronchial tree is a common accident in children. This study aimed to evaluate the safety and outcome of foreign body removal by flexible bronchoscopy using a retrieval basket in chil…
View article: Chest radiographs and computed tomography scans in children with airway foreign body
Chest radiographs and computed tomography scans in children with airway foreign body Open
Purpose: This study aimed to evaluate the diagnostic value of radiologic findings in children with suspected foreign body aspira tion.
Methods: A retrospective medical chart review was done on 32 children with suspected foreign bodies in t…
View article: Current Status of Pediatric Critical Care in Korea: Results of 2015 National Survey
Current Status of Pediatric Critical Care in Korea: Results of 2015 National Survey Open
There is a considerable shortage of PICU beds compared to those in developed countries. In addition, the proportion of PICUs with PCC specialists is much lower than those in the US and European countries.
View article: Effect of Proparacaine in a Mouse Model of Allergic Rhinitis
Effect of Proparacaine in a Mouse Model of Allergic Rhinitis Open
PPC appears to have a therapeutic potential in treatment of allergic rhinitis in a mouse model by reducing eosinophil, goblet cell, and mast cell infiltration in the nasal mucosa.
View article: Spirometry and Bronchodilator Test
Spirometry and Bronchodilator Test Open
Spirometry is a physiological test for assessing the functional aspect of the lungs using an objective indicator to measure the maximum amount of air that a patient can inhale and exhale. Acceptable spirometry testing needs to be conducted…
View article: Usefulness of flexible bronchoscopy in children with suspected pulmonary tuberculosis who have difficulty in sputum expectoration
Usefulness of flexible bronchoscopy in children with suspected pulmonary tuberculosis who have difficulty in sputum expectoration Open
Purpose: To assess the usefulness of flexible bronchoscopy in patients with suspected pulmonary tuberculosis (PTB) who have diffi-culty in sputum expectoration.
Methods: The subjects of this study were patients who were suspected of PTB a…
View article: Usefulness of specific IgE antibody levels to wheat, gluten, and ω-5 gliadin for wheat allergy in Korean children
Usefulness of specific IgE antibody levels to wheat, gluten, and ω-5 gliadin for wheat allergy in Korean children Open
Purpose: The aim of this study was to assess the clinical usefulness and added diagnostic value of specific IgE antibodies to wheat, gluten, and ω-5 gliadin in diagnosing wheat allergy and distinguishing wheat anaphylaxis. Methods: This st…
View article: Foreign body aspiration in 48 children: clinical manifestations and outcomes
Foreign body aspiration in 48 children: clinical manifestations and outcomes Open
Purpose: This study aimed to have a deeper insight into the clinical spectrum of foreign body aspiration in children and to prospect the further clinical implications of early diagnosis. Methods: We conducted a retrospective medical chart …