Joo-Sung Yang
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View article: A novel and safe SmartCap® SC101 to develop the COVID-19 mRNA vaccine STP2104 inducing potent immune responses in humans
A novel and safe SmartCap® SC101 to develop the COVID-19 mRNA vaccine STP2104 inducing potent immune responses in humans Open
We have developed a 5′-capping library screening (CLS) method using over 30 different novel cap analogues. The optimal 5′-cap for the coronavirus disease 2019 (COVID-19) mRNA vaccine STP2104 was selected and applied. This is the first repo…
View article: Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method
Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method Open
Messenger RNA (mRNA) vaccines represent a critical avenue for coronavirus disease 2019 (COVID-19) prevention. We developed a COVID-19 mRNA vaccine encoding a codon-optimized full-length ancestral spike (S) protein with a signal peptide, wh…
View article: P-270 Precision and timing optimization: enhancing fertilization and blastocyst outcomes through ART workflow management
P-270 Precision and timing optimization: enhancing fertilization and blastocyst outcomes through ART workflow management Open
Study question How do ART workflow intervals, including ovum pickup (OPU)-to-denudation, denudation-to-ICSI, OPU-to-ICSI, and ICSI duration, influence fertilization and blastocyst formation? Summary answer Prolonged ICSI duration significa…
View article: P-248 Correlation between artificial intelligence-derived iDAscore and euploid blastocyst outcomes in IVF
P-248 Correlation between artificial intelligence-derived iDAscore and euploid blastocyst outcomes in IVF Open
Study question To evaluate the relationship between the artificial intelligence-based iDAscore and the chromosomal status of human blastocysts, with a focus on the influence of female age. Summary answer The iDAscore demonstrates a signifi…
View article: P-250 Comparison of clinical outcomes between intracytoplasmic morphologically selected sperm injection (IMSI) and conventional intracytoplasmic sperm injection (ICSI) in the same patient group
P-250 Comparison of clinical outcomes between intracytoplasmic morphologically selected sperm injection (IMSI) and conventional intracytoplasmic sperm injection (ICSI) in the same patient group Open
Study question Does IMSI show beneficial effects on fertilization, blastocyst formation, euploid, clinical pregnancy, implantation, and miscarriage rates compared to conventional ICSI in the same patient group? Summary answer IMSI improved…
View article: A Salmonella typhimurium ghost vaccine induces cytokine expression in vitro and immune responses in vivo and protects rats against homologous and heterologous challenges
A Salmonella typhimurium ghost vaccine induces cytokine expression in vitro and immune responses in vivo and protects rats against homologous and heterologous challenges Open
Salmonella enteritidis and Salmonella typhimurium are important food-borne bacterial pathogens, which are responsible for diarrhea and gastroenteritis in humans and animals. In this study, S. typhimurium bacterial ghost (STG) was generated…